Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hui-Jin Yan"'
Autor:
Christopher Power, M. R. Del Bigio, W. Ni, J. B. Johnston, Mengzhou Xue, James Peeling, Michael Mayne, Hui-Jin Yan
Publikováno v:
Scopus-Elsevier
Background and Purpose —Tumor necrosis factor-α (TNF-α) expression is increased in brain after cerebral ischemia, although little is known about its abundance and role in intracerebral hemorrhage (ICH). A TNF-α–specific antisense oligodeoxynuc
Publikováno v:
Brain Research. 795:63-70
Iron compounds formed in the degradation of a hematoma can accelerate the formation of free radicals in adjacent ischemic or hypoperfused tissue. The purpose of this study was to examine the efficacy of compounds that quench free radicals in improvin
Publikováno v:
Stroke. 27:2312-2320
Background and Purpose Intracerebral hemorrhage is associated with a considerable proportion of strokes and head injuries. The mechanism of brain cell injury associated with hemorrhage may be different from that due to pure ischemia. Therefore, it is
Publikováno v:
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 15(3)
Minocycline reduces infarct volume measured up to 1 week after focal cerebral ischemia, but it has not been shown that this results in lasting improvement in functional outcome. This study examined behavioral outcome in rats out to 3 weeks after foca
Publikováno v:
Journal of the neurological sciences. 192(1-2)
Neuronal and glial cell death in the striatum of a rat model of collagenase-induced intracerebral hemorrhage begins at 1 day and continues for at least 3 weeks. We hypothesized that administration of a neurotrophic agent would reduce neuronal loss in
Autor:
Jonathan D. Geiger, Christopher Power, Marc R. Del Bigio, James Peeling, Michael Mayne, Julie Fotheringham, Hui Jin Yan
Publikováno v:
Annals of neurology. 49(6)
The ubiquitous neuromodulator adenosine inhibits the production of several proinflammatory cytokines through activation of specific cell-surface adenosine receptors. We demonstrated recently that antisense oligonucleotides to tumor necrosis factor-al
Publikováno v:
Experimental neurology. 167(2)
Beginning 15 min after induction of intracerebral hemorrhage (ICH) by intrastriatal administration of collagenase, rats were treated intramuscularly with FK-506 (3 mg/kg) or with vehicle. Treatment was repeated daily for 7 days. MR imaging 1, 7, and
Publikováno v:
Stroke. 30(11)
Background and Purpose —Hypertension is a major risk factor for ischemic and hemorrhagic stroke and may also cause more chronic and subtle brain injury. Progressive brain changes in a rat model of renal hypertension have been assessed to better und
Publikováno v:
Neurological research. 21(4)
Inflammatory cells are postulated to mediate some of the brain damage following ischemic stroke. Intracerebral hemorrhage is associated with more inflammation than ischemic stroke. We tested the sulfated polysaccharide fucoidan, which has been report
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 25:S29-S29
We demonstrated previously that minocycline is neuroprotective in a rat model of collagenase-induced intrastriatal hemorrhage through depression of inflammation. Minocycline treatment significantly reduced necrotic damage and apoptic cell death, supp