Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hui-Hyun Kim"'
Autor:
Young Hoon Kim, Dong Won Jeong, Yoo Seok Yoon, Hui-Hyun Kim, Kang Choon Lee, Hye Suk Lee, Hye Young Ji
Publikováno v:
Rapid Communications in Mass Spectrometry. 20:2127-2132
A rapid, sensitive and selective method for the determination of gabapentin in human plasma was developed using hydrophilic interaction liquid chromatography/tandem mass spectrometry (HILIC/MS/MS). The devised method involved protein precipitation wi
Autor:
Hye Suk Lee, John Kim, Hye Young Ji, Hui Hyun Kim, Byung Mu Lee, Yoon Chul Kim, Dong Hwan Sohn
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 68:2239-2247
The absorption and pharmacokinetics of an active component of Salvia miltiorrhiza, lithospermic acid B (LSB), was investigated after intravenous and oral administration of doses of 10 or 50 mg LSB/kg to rats. Concentrations of LSB were determined by
Publikováno v:
Journal of Separation Science. 28:1818-1822
KR-31831 ((2S,3R,4S)-4-(((1H-imidazol-2-yl)methyl)(4-chlorophenyl)amino)-6-amino-2-(dimethoxymethyl)-2-methyl-3,4-dihydro-2H-chromen-3-ol) is a novel antiangiogenic agent. In vitro and in vivo metabolism of KR-31831 in rats has been investigated usin
Autor:
Seonkyoung Lee, Hye Young Ji, Hui Hyun Kim, Soon Ai Kim, Hye Won Lee, Hye Suk Lee, Kyu Yang Yi
Publikováno v:
Drug Development Research. 66:40-49
The in vitro metabolism and the transport of a novel anti-angiogenic agent KR-31831, (2R,3R,4S)-6-amino-4-[N-(4-chlorophenyl)-N-(1H-imidazol-2-ylmethyl)amino]-3-hydroxy-2-dimethyoxymethyl-3,4-dihydro-2-methyl-2H-1-benzopyran were investigated. Liquid
Publikováno v:
Toxicology Letters. 155:103-114
KR-60436 ([1-(4-methoxy-2-methylphenyl)-4-[(2-hydroxyethyl)amino]-6-trifluoromethoxy-2,3-dihydropyrrolo [3,2-c]quinoline]) is a new reversible H+/K+-ATPase inhibitor. The isoforms of human liver cytochrome P450 (CYP) responsible for the hepatic trans
Autor:
So Hee Kim, Hui Hyun Kim, Hye Young Ji, Hye Suk Lee, In Bok Paek, Ya Moon, Myung Geol Lee, Hye Won Lee
Publikováno v:
Analytical Letters. 38:99-110
A Liquid chromatography and tandem mass spectrometry (LC/MS/MS) method has been described for the simultaneous determination of ipriflavone and its main metabolites, 7‐hydroxy‐3‐phenyl‐chromen‐4‐one (M1) and 7‐(4‐oxo‐3‐phenyl‐4H
Autor:
Hui-Hyun Kim, Jae Baek Kim, Hye Suk Lee, Yoon Chul Kim, Hye Won Lee, Hae Kyoung Kim, Dong Hwan Sohn, Hye Young Ji
Publikováno v:
Analytical Letters. 37:1307-1318
A rapid, sensitive, and selective liquid chromatography–mass spectrometric (LC/MS) method for the determination of compound K, a ginseng saponin metabolite, in rat plasma was developed. Compound K and internal standard, lithospermic acid B, dimethy
Publikováno v:
Archives of Pharmacal Research. 27:1202-1206
A rapid, sensitive and selective liquid chromatography-tandem mass spectrometric (LC-MS/ MS) method for the determination of lithospermic acid B (LSB) in rat serum was developed. LSB and internal standard, 7-hydroxy-3-phenyl-chromen-4-one (HPC) were
Publikováno v:
Archives of Pharmacal Research. 27:901-905
A rapid, sensitive and selective hydrophilic interaction liquid chromatography-tandem mass spectrometric (HILIC-MS/MS) method for the determination of tiapride in human plasma was developed. Tiapride and internal standard, metoclopramide were extract
Publikováno v:
Xenobiotica. 34:973-982
1. The purpose of this paper was to characterize cytochrome P450 (CYP) enzymes involved in N-dealkylation of a new oral erectogenic, DA-8159 to DA-8164, a major circulating active metabolite, in human liver microsomes and to investigate the inhibitor