Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Hui-Huang Huang"'
Autor:
You-Yuan Wang, Cheng Zhen, Wei Hu, Hui-Huang Huang, Yan-Jun Li, Ming-Ju Zhou, Jing Li, Yu-Long Fu, Peng Zhang, Xiao-Yu Li, Tao Yang, Jin-Wen Song, Xing Fan, Jun Zou, Si-Run Meng, Ya-Qin Qin, Yan-Mei Jiao, Ruonan Xu, Ji-Yuan Zhang, Chun-Bao Zhou, Jin-Hong Yuan, Lei Huang, Ming Shi, Liang Cheng, Fu-Sheng Wang, Chao Zhang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract CD8 + T cells are essential for long-lasting HIV-1 control and have been harnessed to develop therapeutic and preventive approaches for people living with HIV-1 (PLWH). HIV-1 infection induces marked metabolic alterations. However, it is unc
Externí odkaz:
https://doaj.org/article/27b6d065388d453b9c98d17d351d0282
Autor:
Lin-Yu Wan, Hui-Huang Huang, Cheng Zhen, Si-Yuan Chen, Bing Song, Wen-Jing Cao, Li-Li Shen, Ming-Ju Zhou, Xiao-Chang Zhang, Ruonan Xu, Xing Fan, Ji-Yuan Zhang, Ming Shi, Chao Zhang, Yan-Mei Jiao, Jin-Wen Song, Fu-Sheng Wang
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTChronic inflammation and T cell dysregulation persist in individuals infected with human immunodeficiency virus type 1 (HIV-1), even after successful antiretroviral treatment. The mechanism involved is not fully understood. Here, we used Olin
Externí odkaz:
https://doaj.org/article/4f52b506b44e49eeadf5c41cc28f051e
Autor:
Yan-Ze Shi, Hui-Huang Huang, Xin-Hua Wang, Bing Song, Tian-Jun Jiang, Min-Rui Yu, Ze-Rui Wang, Rui-Ting Li, Yan-Mei Jiao, Xin Su, Fu-Sheng Wang
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 115 (2024)
(1) Background: The objective of this study was to investigate the prevalence of genetic diversity and drug resistance mutations among people living with HIV (PLWH) attending clinics in Beijing. (2) Methods: A retrospective analysis was conducted on
Externí odkaz:
https://doaj.org/article/962ce90c0a194e11b5da7941c8987748
Autor:
Meng-Meng Qu, Bing Song, Bao-Peng Yang, Zerui Wang, Minrui Yu, Yi Zhang, Chao Zhang, Jin-Wen Song, Xing Fan, Ruonan Xu, Ji-Yuan Zhang, Chun-Bao Zhou, Fengxia Du, Fu-Sheng Wang, Hui-Huang Huang, Yan-Mei Jiao
Publikováno v:
Viruses, Vol 15, Iss 12, p 2427 (2023)
People living with human immunodeficiency virus (PLWH) are a vulnerable population with a higher risk of severe coronavirus disease 2019 (COVID-19); therefore, vaccination is recommended as a priority. Data on viral reservoirs and immunologic outcome
Externí odkaz:
https://doaj.org/article/fe3946e589c543f8bae56f9b1086d8a4
Autor:
Peng Xia, Xu-Dong Xing, Cui-Xian Yang, Xue-Jiao Liao, Fu-Hua Liu, Hui-Huang Huang, Chao Zhang, Jin-Wen Song, Yan-Mei Jiao, Ming Shi, Tian-Jun Jiang, Chun-Bao Zhou, Xi-Cheng Wang, Qing He, Qing-Lei Zeng, Fu-Sheng Wang, Ji-Yuan Zhang
Publikováno v:
Military Medical Research, Vol 9, Iss 1, Pp 1-19 (2022)
Abstract Background Mucosal-associated invariant T (MAIT) cells are systemically depleted in human immunodeficiency virus type 1 (HIV-1) infected patients and are not replenished even after successful combined antiretroviral therapy (cART). This stud
Externí odkaz:
https://doaj.org/article/c991a54f21bb431da1045fcdba76335f
Autor:
Xiang-Ming Wang, Ji-Yuan Zhang, Xudong Xing, Hui-Huang Huang, Peng Xia, Xiao-Peng Dai, Wei Hu, Chao Zhang, Jin-Wen Song, Xing Fan, Feng-Ying Wu, Fu-Hua Liu, Yuehua Ke, Yifan Zhao, Tian-Jun Jiang, Li-Feng Wang, Yan-Mei Jiao, Ruo-Nan Xu, Lei Jin, Ming Shi, Fan Bai, Fu-Sheng Wang
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract To obtain a comprehensive scenario of T cell profiles and synergistic immune responses, we performed single-cell RNA sequencing (scRNA-seq) on the peripheral T cells of 14 individuals with chronic human immunodeficiency virus 1 (HIV-1) infec
Externí odkaz:
https://doaj.org/article/a518508a8eef4a02af3e6756fccf3e53
Autor:
Ruonan Xu, Ji-Yuan Zhang, Bo Tu, Zhe Xu, Hui-Huang Huang, Lei Huang, Yan-Mei Jiao, Tao Yang, Chao Zhang, En-Qiang Qin, Tian-Jun Jiang, Yun-Bo Xie, Yuan-Yuan Li, Lei Jin, Chun-Bao Zhou, Ming Shi, Mei Guo, Hui-Sheng Ai, Linqi Zhang, Fu-Sheng Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-8 (2021)
Abstract Severely immunosuppressed AIDS patients with recurrent opportunistic infections (OIs) represent an unmet medical need even in the era of antiretroviral therapy (ART). Here we report the development of a human leukocyte antigen (HLA)-mismatch
Externí odkaz:
https://doaj.org/article/6148cdf218964264a0f2032a7bf55648
Autor:
Wei Hu, Yan-Jun Li, Cheng Zhen, You-Yuan Wang, Hui-Huang Huang, Jun Zou, Yan-Qing Zheng, Gui-Chan Huang, Si-Run Meng, Jie-Hua Jin, Jing Li, Ming-Ju Zhou, Yu-Long Fu, Peng Zhang, Xiao-Yu Li, Tao Yang, Xiu-Wen Wang, Xiu-Han Yang, Jin-Wen Song, Xing Fan, Yan-Mei Jiao, Ruo-Nan Xu, Ji-Yuan Zhang, Chun-Bao Zhou, Jin-Hong Yuan, Lei Huang, Ya-Qin Qin, Feng-Yao Wu, Ming Shi, Fu-Sheng Wang, Chao Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recent studies highlighted that CD8+ T cells are necessary for restraining reservoir in HIV-1-infected individuals who undergo antiretroviral therapy (ART), whereas the underlying cellular and molecular mechanisms remain largely unknown. Here, we enr
Externí odkaz:
https://doaj.org/article/9ceb09f7bcb747d9bf7b54f842701e8e
Autor:
An-Liang Guo, Yan-Mei Jiao, Qi-Wen Zhao, Hui-Huang Huang, Jian-Ning Deng, Chao Zhang, Xing Fan, Ruo-Nan Xu, Ji-Yuan Zhang, Cheng Zhen, Zhi-Man Xie, Ying-Mei Qin, Jian-Qing Xu, Yu Yang, Ming Shi, Lei Huang, Jin-Wen Song, Fu-Sheng Wang
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103794- (2022)
Summary: Background: B cell follicles are immune-privileged sites where intensive HIV-1 replication and latency occur, preventing a permanent cure. Recent study showed that CXCR5+ NK cells in B cell follicles can inhibit SIV replication in African gr
Externí odkaz:
https://doaj.org/article/bdccef29f9ad478c89ba15fa0da046fd
Autor:
An-Liang Guo, Jin-Fang Zhao, Lin Gao, Hui-Huang Huang, Ji-Yuan Zhang, Chao Zhang, Jin-Wen Song, Ruo-Nan Xu, Xing Fan, Ming Shi, Yan-Mei Jiao, Fu-Sheng Wang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Exhaustion of HIV-1-specific CD8+ T cells prevents optimal control of HIV-1 infection. Identifying unconventional CD8+ T cell subsets to effectively control HIV-1 replication is vital. In this study, the role of CD11c+ CD8+ T cells during HIV-1 infec
Externí odkaz:
https://doaj.org/article/e3479d8f1d414ab0a065188c3ee014f4