Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Hui-Fu Wang"'
Autor:
Xiao-He Hou, John Suckling, Xue-Ning Shen, Yong Liu, Chuan-Tao Zuo, Yu-Yuan Huang, Hong-Qi Li, Hui-Fu Wang, Chen-Chen Tan, Mei Cui, Qiang Dong, Lan Tan, Jin-Tai Yu, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Early prevention of Alzheimer’s disease (AD) is a feasible way to delay AD onset and progression. Information on AD prediction at the individual patient level will be useful in AD prevention. In this study, we aim to develop ris
Externí odkaz:
https://doaj.org/article/29e263d09a744ddca09eb5252a873c92
Autor:
Yu Guo, Xue-Ning Shen, Shu-Yi Huang, Shu-Fen Chen, Hui-Fu Wang, Wei Zhang, Ya-Ru Zhang, Wei Cheng, Mei Cui, Qiang Dong, Jin-Tai Yu
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract There is a dire need for reliable biomarkers to solidify an early and accurate diagnosis of multiple system atrophy (MSA). We sought to compare the ability of emerging plasma markers in distinguishing MSA from its mimics and healthy controls
Externí odkaz:
https://doaj.org/article/16b427f0f7154963ab99a411ea93e789
Autor:
Jie‐Qiong Li, Ya‐Ru Zhang, Hui‐Fu Wang, Yu Guo, Xue‐Ning Shen, Meng‐Meng Li, Jing‐Hui Song, Lan Tan, An‐Mu Xie, Jin‐Tai Yu
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract INTRODUCTION We analyzed relationships among peripheral immunity markers, cognition, Alzheimer's disease (AD)‐related biomarkers, and neuroimaging to understand peripheral immunity involvement in AD. METHODS Peripheral immunity markers wer
Externí odkaz:
https://doaj.org/article/b6cce8ab502040e98d6a00010efd2b47
Autor:
Yu Guo, Xue-Ning Shen, Hui-Fu Wang, Shi-Dong Chen, Ya-Ru Zhang, Shu-Fen Chen, Mei Cui, Wei Cheng, Qiang Dong, Tao Ma, Jin-Tai Yu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Failures in drug trials strengthen the necessity to further determine the neuropathological events during the development of Alzheimer’s disease (AD). We sought to investigate the dynamic changes and performance of plasma biomar
Externí odkaz:
https://doaj.org/article/32989bc50243406da23904a7d9e12c89
Autor:
Zhi-Bo Wang, Ya-Hui Ma, Yan Sun, Lan Tan, Hui-Fu Wang, Jin-Tai Yu, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-11 (2022)
Abstract Background Dysfunction of glial cell communication is involved in Alzheimer’s disease (AD) pathogenesis, and the recent study reported that astrocytic secreted interleukin-3 (IL-3) participated in astrocyte–microglia crosstalk and restri
Externí odkaz:
https://doaj.org/article/64bfabf0219a49aebbf7bea8d498b947
Autor:
Zuo-Teng Wang, Yan Fu, Ya-Ru Zhang, Shi-Dong Chen, Shu-Yi Huang, Liu Yang, Hong-Qi Li, Ya-Nan Ou, Jian-Feng Feng, Qiang Dong, Wei Cheng, Lan Tan, Hui-Fu Wang, Jin-Tai Yu
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Based on risk profiles, several approaches for predicting dementia risk have been developed. Predicting the risk of dementia with accuracy is a significant clinical challenge. The goal was to create a modified dementia risk score (MDRS) base
Externí odkaz:
https://doaj.org/article/bf97206ae43c4fd7aff474eecd043327
Autor:
Xue-Ning Shen, Kai-Min Wu, Yu-Yuan Huang, Yu Guo, Shu-Yi Huang, Ya-Ru Zhang, Shu-Fen Chen, Hui-Fu Wang, Wei Zhang, Wei Cheng, Mei Cui, Qiang Dong, Jin-Tai Yu
Publikováno v:
Neurobiology of Disease, Vol 181, Iss , Pp 106112- (2023)
Background and objectives: Plasma neurofilament light (NfL), glial fibrillary acidic protein (GFAP), phosphorylated-tau (p-tau), and β-amyloid (Aβ) have emerged as promising markers in several neurodegenerative disorders, but whether they can be us
Externí odkaz:
https://doaj.org/article/e61b73ef76a244f6b30b8affa499226f
Autor:
Ya-Ru Zhang, Liu Yang, Hui-Fu Wang, Bang-Sheng Wu, Shu-Yi Huang, Wei Cheng, Jian-Feng Feng, Jin-Tai Yu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Immune system dysregulation plays a vital role in the pathogenesis of neurodegenerative diseases, even considered to be as important as classical pathological protein aggregation assumption. However, the associations of immune-med
Externí odkaz:
https://doaj.org/article/05f187f11b9546469afddf532a5cdb8a
Autor:
Hui-Fu Wang, Wei Zhang, Edmund T. Rolls, Yuzhu Li, Linbo Wang, Ya-Hui Ma, Jujiao Kang, Jianfeng Feng, Jin-Tai Yu, Wei Cheng
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104336- (2022)
Summary: Background: Hearing impairment was recently identified as the most prominent risk factor for dementia. However, the mechanisms underlying the link between hearing impairment and dementia are still unclear. Methods: We investigated the associ
Externí odkaz:
https://doaj.org/article/0f391d64bc0449dca778538b92c05273
Publikováno v:
EClinicalMedicine, Vol 53, Iss , Pp 101665- (2022)
Summary: Background: The existing dementia risk models are limited to known risk factors and traditional statistical methods. We aimed to employ machine learning (ML) to develop a novel dementia prediction model by leveraging a rich-phenotypic variab
Externí odkaz:
https://doaj.org/article/59777100cb3346f485b4b673b52c5f42