Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Hui-Fang Liu"'
Autor:
Juan Chen, Cheng-Hui Zhang, Tao Tao, Xian Zhang, Yan Lin, Fang-Bin Wang, Hui-Fang Liu, Jian Liu
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Aberrant RNA editing has emerged as a pivotal factor in the pathogenesis of hepatocellular carcinoma (HCC), but the impact of RNA co-editing within HCC remains underexplored. We used a multi-step algorithm to construct an RNA co-editing netw
Externí odkaz:
https://doaj.org/article/2c8e5f9963d64da28acb1a36052db97a
Autor:
Philip Wing‐Lok Ho, Lingfei Li, Hui‐Fang Liu, Zoe Yuen‐Kiu Choi, Eunice Eun Seo Chang, Shirley Yin‐Yu Pang, Yasine Malki, Chi‐Ting Leung, Michelle Hiu‐Wai Kung, David Boyer Ramsden, Shu‐Leong Ho
Publikováno v:
Brain and Behavior, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract Background Leucine‐rich repeat kinase 2 (LRRK2) mutation is a common genetic risk factor of Parkinson's disease (PD). Presynaptic dysfunction is an early pathogenic event associated with dopamine (DA) dysregulation in striatum of the brain
Externí odkaz:
https://doaj.org/article/2ee981caa3584b2cabee05ffa1a8e5db
Autor:
Eunice Eun Seo Chang, Philip Wing-Lok Ho, Hui-Fang Liu, Shirley Yin-Yu Pang, Chi-Ting Leung, Yasine Malki, Zoe Yuen-Kiu Choi, David Boyer Ramsden, Shu-Leong Ho
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-19 (2022)
Abstract Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are one of the most frequent genetic causes of both familial and sporadic Parkinson’s disease (PD). Mounting evidence has demonstrated pathological similarities between LRRK2-assoc
Externí odkaz:
https://doaj.org/article/06ce894a7bfb40c5b4c49bef2bb50a60
Autor:
Shirley Yin-Yu Pang, Rachel Cheuk Nam Lo, Philip Wing-Lok Ho, Hui-Fang Liu, Eunice Eun Seo Chang, Chi-Ting Leung, Yasine Malki, Zoe Yuen-Kiu Choi, Wing Yan Wong, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Mutations in leucine-rich repeat kinase 2 (LRRK2) and glucocerebrosidase (GBA) represent two most common genetic causes of Parkinson’s disease (PD). Both genes are important in the autophagic-lysosomal pathway (ALP), defects of which are a
Externí odkaz:
https://doaj.org/article/b6fc3201296c4ede996e68a53646446e
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 879-891 (2021)
Summary: RNA editing is widely involved in stem cell differentiation and development; however, RNA editing events during human cardiomyocyte differentiation have not yet been characterized and elucidated. Here, we identified genome-wide RNA editing s
Externí odkaz:
https://doaj.org/article/a6edee6683014e7b8c1d6c1ddca9ee3b
Autor:
Yun-shan YANG, Xiao-xia GUO, Hui-fang LIU, Guang-zhou LIU, Wan-mao LIU, Bo MING, Rui-zhi XIE, Ke-ru WANG, Peng HOU, Shao-kun LI
Publikováno v:
Journal of Integrative Agriculture, Vol 20, Iss 2, Pp 482-493 (2021)
The uneven distribution of solar radiation is one of the main reasons for the variations in the yield gap between different regions in China and other countries of the world. In this study, different solar radiation levels were created by shading and
Externí odkaz:
https://doaj.org/article/353375f449c24e9e9362a23b24c8c4ff
Autor:
Shirley Yin-Yu Pang, Philip Wing-Lok Ho, Hui-Fang Liu, Chi-Ting Leung, Lingfei Li, Eunice Eun Seo Chang, David Boyer Ramsden, Shu-Leong Ho
Publikováno v:
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-11 (2019)
Abstract Background Parkinson’s disease (PD) is characterized by dopaminergic neuronal loss in the substantia nigra pars compacta and intracellular inclusions called Lewy bodies (LB). During the course of disease, misfolded α-synuclein, the major
Externí odkaz:
https://doaj.org/article/43d50c8ae87c483988f526d2505c7897
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 4, p e1008951 (2021)
The binding affinities of protein-nucleic acid interactions could be altered due to missense mutations occurring in DNA- or RNA-binding proteins, therefore resulting in various diseases. Unfortunately, a systematic comparison and prediction of the ef
Externí odkaz:
https://doaj.org/article/a0d34d0b8c774d898ff4c16049cd3650
Autor:
Jing Jin, Guan-Jian Li, Feng-Sen Li, Jing Wang, Jing Jing, Zheng Li, Xiao-Yi Xin, Qian Zheng, Kun-Ling Wang, Hui-Fang Liu, Si-Ming Tao
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
Objective This study investigated the correlations of digit ratio (relative length of second and fourth fingers, 2D: 4D) and muscular strength with the progression of chronic obstructive pulmonary disease (COPD). Methods In total, 164 patients with C
Externí odkaz:
https://doaj.org/article/795c377cd9b647dabe6e429689d04435
Publikováno v:
Complexity, Vol 2018 (2018)
We aim to study the characteristics and mechanism of the aerodynamic noise sources for a high-speed train in a tunnel at the speeds of 50 m/s, 70 m/s, 83 m/s, and 97 m/s by means of the numerical wind tunnel model and the nonreflective boundary condi
Externí odkaz:
https://doaj.org/article/0f57e9b3c7f2416e9bbdbcadf9c878fc