Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Hui-Chun Yu"'
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Objectives To investigate the roles of Ca2+ influx-regulated circular RNAs (circRNAs) in T cells from patients with systemic lupus erythematosus (SLE). Methods The expression profile of circRNAs in Jurkat cells, co-cultured with and without
Externí odkaz:
https://doaj.org/article/92b7d364f99d4fadba40ffbb873b6abd
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1873 (2024)
Ankylosing spondylitis (AS) is a chronic inflammatory disorder characterized by inflammatory back pain and bony fusion of vertebral joints. Genetic associations and environmental factors have been proposed to explain the immunopathogenesis of AS. In
Externí odkaz:
https://doaj.org/article/40addcf6cb68401d9f224a1366a54534
Publikováno v:
Mediators of Inflammation, Vol 2023 (2023)
This study aimed to identify the abnormal expression of long noncoding RNAs (lncRNAs) in T cells from patients with vitiligo and to investigate their functional roles in the immune system. Using microarray analysis, the expression levels of RNA trans
Externí odkaz:
https://doaj.org/article/a6db17fcd5914acf8030a1f06c53b4a8
Autor:
Hui-Chun Yu, Kuang-Yung Huang, Ming-Chi Lu, Hsien-Yu Huang Tseng, Su-Qin Liu, Ning-Sheng Lai, Hsien-Bin Huang
Publikováno v:
Medicina, Vol 58, Iss 10, p 1411 (2022)
Background and Objectives: Ankylosing spondylitis (AS) is a chronic inflammatory disease and is highly linked with the expression of the human leukocytic antigen-B*27 (HLA-B*27) genotype. HLA-B*27 heavy chain (B*27-HC) has an innate characteristic to
Externí odkaz:
https://doaj.org/article/2c1efbba097c442e9370a65fad2a950c
Autor:
Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung, Kuang-Yung Huang, Hsien-Bin Huang, Ming-Chi Lu
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Objective To investigate the expression of peptidylarginine deiminases (PADIs) during macrophage differentiation and its role in inflammatory responses. Methods The protein expression of PADI2, PADI4, and citrullinated histone 3 in U937 cell
Externí odkaz:
https://doaj.org/article/4e63b97f957d43aa9f4620cdf7f74c63
The roles of anti-citrullinated protein antibodies in the immunopathogenesis of rheumatoid arthritis
Autor:
Hui-Chun Yu, Ming-Chi Lu
Publikováno v:
Tzu-Chi Medical Journal, Vol 31, Iss 1, Pp 5-10 (2019)
Rheumatoid arthritis (RA) is a common systemic autoimmune disease. Its major manifestation is persistent joint inflammation, which can lead to bone destruction and severe disability. The immunopathogenesis of RA is very complex, involving both innate
Externí odkaz:
https://doaj.org/article/bace1568bb714af690a76797b971483f
Autor:
Hui-Chun Yu, Kuang-Yung Huang, Ming-Chi Lu, Hsien-Yu Huang Tseng, Su-Qin Liu, Ning-Sheng Lai, Hsien-Bin Huang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Ankylosing spondylitis (AS) is a chronic inflammatory disease that mainly affects the spine. AS is highly associated with the expression of HLA-B27. Up to 95% AS patients are HLA-B27-positive. However, only 1%–2% of the HLA-B27-positive carriers su
Externí odkaz:
https://doaj.org/article/a2eb7f93247640ff93ee096c2c6b9087
Autor:
Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung, Kuang-Yung Huang, Hsien-Bin Huang, Ming-Chi Lu
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-10 (2018)
Abstract Background Interleukin (IL)-23 can facilitate the differentiation of IL-17-producing helper T cells (Th17). The IL-23/IL-17 axis is known to play a key role in the immunopathogenesis of ankylosing spondylitis (AS). We hypothesized that the e
Externí odkaz:
https://doaj.org/article/f40949e86c4d48a28d59903d293372f1
Autor:
Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung, Kuang-Yung Huang, Hsien-Bin Huang, Ming-Chi Lu
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Tumor necrosis factor-alpha (TNF-α) can cause diverse T cell dysfunctions in patients with rheumatoid arthritis (RA). It is involved in the regulation of microRNAs (miRNAs) expression in different cell types. We hypothesized that
Externí odkaz:
https://doaj.org/article/e6db244087b8448e96bf59f31e27f7ac
Publikováno v:
Medicina, Vol 56, Iss 10, p 545 (2020)
Background and objectives: To investigate the serum procalcitonin (PCT) levels among patients with rheumatoid arthritis (RA) without active infection compared with healthy controls and to understand the relationship of PCT with RA disease activity, a
Externí odkaz:
https://doaj.org/article/433a50628c2a46da804b74dc9addcbc6