Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Hui Xin Ong"'
Autor:
Mathew N. Leslie, Zara Sheikh, Dikaia Xenaki, Brian G. Oliver, Paul M. Young, Daniela Traini, Hui Xin Ong
Publikováno v:
Medicine in Drug Discovery, Vol 23, Iss , Pp 100194- (2024)
Emphysema is a respiratory disease that causes the progressive loss of lung extracellular matrix (ECM) organisation, subsequently undermining lung integrity and reducing lung function. Fibroblasts must constantly repair damage to the lungs to preserv
Externí odkaz:
https://doaj.org/article/d332cdbeb9d14043a60d7315344f7f8e
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 12, Pp 1691-1699 (2022)
Coronavirus is a type of acute atypical respiratory disease representing the leading cause of death worldwide. Eucalyptol (EUC) known also as 1,8-cineole is a potential inhibitor candidate for COVID-19 (main protease-Mpro) with effective antiviral pr
Externí odkaz:
https://doaj.org/article/1fc6214f6a934379bc13f07b90071f02
Autor:
Hadi Mahmodi, Christopher G Poulton, Mathew N Leslie, Glenn Oldham, Hui Xin Ong, Steven J Langford, Irina V Kabakova
Publikováno v:
JPhys Photonics, Vol 6, Iss 2, p 025009 (2024)
Brillouin microscopy has recently emerged as a new bio-imaging modality that provides information on the microscale mechanical properties of biological materials, cells and tissues. The data collected in a typical Brillouin microscopy experiment repr
Externí odkaz:
https://doaj.org/article/42d5e672c801489186a5e0d1f86222b3
Autor:
Chee Yien Lee, Hui Xin Ong, Chew Yee Tan, Suet Ee Low, Lai Yee Phang, Jyhmirn Lai, Peck Toung Ooi, Michelle Wai Cheng Fong
Publikováno v:
Pathogens, Vol 12, Iss 2, p 308 (2023)
Glaesserella (Haemophilus) parasuis, the etiological agent of Glässer’s disease, is an economically significant pathogen commonly associated with serofibrinous polyserositis, arthritis, fibrinous bronchopneumonia and/or meningitis. This study is t
Externí odkaz:
https://doaj.org/article/c3bd5d19d2464068b5d8ee5405ca2d45
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 146 (2022)
A central characteristic of emphysematous progression is the continuous destruction of the lung extracellular matrix (ECM). Current treatments for emphysema have only addressed symptoms rather than preventing or reversing the loss of lung ECM. Nitrof
Externí odkaz:
https://doaj.org/article/160e01b14b234baeabaf3b57c7734999
Autor:
Hanieh Gholizadeh, Shaokoon Cheng, Agisilaos Kourmatzis, Hanwen Xing, Daniela Traini, Paul M. Young, Hui Xin Ong
Publikováno v:
Bioengineering, Vol 9, Iss 4, p 150 (2022)
Developing novel drug formulations and progressing them to the clinical environment relies on preclinical in vitro studies and animal tests to evaluate efficacy and toxicity. However, these current techniques have failed to accurately predict the cli
Externí odkaz:
https://doaj.org/article/9613b930395f494998a859a1fca9eaab
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
For the past 50 years, the route of inhalation has been utilized to administer therapies to treat a variety of respiratory and pulmonary diseases. When compared with other drug administration routes, inhalation offers a targeted, non-invasive approac
Externí odkaz:
https://doaj.org/article/d815feb2700f494a8bd6e510cb36de96
Publikováno v:
Bioengineering, Vol 8, Iss 8, p 110 (2021)
The emphysema death toll has steadily risen over recent decades, causing the disease to become the third most common cause of death worldwide in 2019. Emphysema is currently incurable and could be due to a genetic condition (Alpha-1 antitrypsin defic
Externí odkaz:
https://doaj.org/article/c1c94690286d4bb6b3af0514dba110ff
Autor:
Keith Zhi Xian Toh, Ming Yi Koh, Jamie S.Y. Ho, Kathleen Hui Xin Ong, Yong Qin Lee, Xintong Chen, Jun Tao Fang, Elliot Yeung Chong, Isis Claire Z.Y. Lim, Yao Hao Teo, Yao Neng Teo, Christopher Y.K. Chua, Yinghao Lim, Bernard P.L. Chan, Vijay K. Sharma, Leonard L.L. Yeo, Ching Hui Sia, Benjamin Y.Q. Tan
Publikováno v:
Cerebrovascular Diseases. :1-8
Introduction: A patent foramen ovale (PFO) may coexist with other potential embolic sources (PESs) in patients with embolic stroke of undetermined source (ESUS), leading to difficulty in attributing the stroke to either the PFO or other PESs. We aime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c8f6434b066fd5bc9aa8de44dff3f2
https://doi.org/10.1159/000527791
https://doi.org/10.1159/000527791
Autor:
Alberto Baldelli, Mohammed A. Boraey, Hale Oguzlu, Aylin Cidem, Athenea Pascual Rodriguez, Hui Xin Ong, Feng Jiang, Mattia Bacca, Andrew Thamboo, Daniela Traini, Anubhav Pratap-Singh
Publikováno v:
Drug Discovery Today. 27:2300-2308
In this review, we present the potential of nasal dry powders to deliver stable bioactive compounds and their manufacture using spray-drying (SD) techniques to achieve encapsulation. We also review currently approved and experimental excipients used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b856d3ca5d9d33ce5b10ac5aca675d
https://doi.org/10.1016/j.drudis.2022.04.012
https://doi.org/10.1016/j.drudis.2022.04.012