Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Hui Ming Ge"'
Autor:
Hong Jie Zhu, Bo Zhang, Wanqing Wei, Shuang He Liu, Lang Xiang, Jiapeng Zhu, Rui Hua Jiao, Yasuhiro Igarashi, Ghader Bashiri, Yong Liang, Ren Xiang Tan, Hui Ming Ge
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Macrocyclization is an important process in bioactive natural product synthesis. Here, the authors report on the study of a macrocyclic ring constructing enzyme in the biosynthesis of alchivemycin A and using gene deletion, biochemical assays and iso
Externí odkaz:
https://doaj.org/article/c4b5a7495b704b4bbee8ca1abd98b0d5
Autor:
Kai Biao Wang, Wen Wang, Bo Zhang, Xin Wang, Yu Chen, Hong Jie Zhu, Yong Liang, Ren Xiang Tan, Hui Ming Ge
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Streptoseomycin is a potent antibiotic that contains a pentacyclic 5/14/10/6/6 ring system. Here, the authors report the enzymatic and non-enzymatic steps of the downstream modification of streptoseomycin biosynthesis and show a [6 + 4]-cycloaddition
Externí odkaz:
https://doaj.org/article/7246c7166a5548fca61b1e86049ac423
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 2677-2682 (2014)
An unusual C18 norditerpenoid, aspergiloid I (1), was isolated from the culture broth of Aspergillus sp. YXf3, an endophytic fungus derived from Ginkgo biloba. Its structure was unambiguously established by analysis of HRMS–ESI and spectroscopic da
Externí odkaz:
https://doaj.org/article/f3f95e5d8bc2419a85eb0160888690a9
Autor:
Yi Ling Hu, Qi Zhang, Shuang He Liu, Jia Li Sun, Fang Zhou Yin, Zi Ru Wang, Jing Shi, Rui Hua Jiao, Hui Ming Ge
Publikováno v:
Chemical Science. 14:3661-3667
We built a Streptomyces expression system to discovery bacterial terpenoids. Though genome mining and expression of terpene BGCs, 11 terpene skeletons including 3 new ones, and 18 novel distinct terpenoids were isolated and characterized.
Autor:
Zhi-Kai, Guo, Wen-Yong, Zhu, Li-Xing, Zhao, Yan-Chi, Chen, Sui-Jun, Li, Ping, Cheng, Hui-Ming, Ge, Ren-Xiang, Tan, Rui-Hua, Jiao
Publikováno v:
Chinese Journal of Natural Medicines. 20:627-632
Six new (1-6) and seven known depsidones (7-13) were isolated from the culture of an ant (Monomorium chinensis)-derived fungus Spiromastix sp. MY-1. Their structures were elucidated by extensive spectroscopic analysis including high resolution MS, 1D
Autor:
Yang Zhao, Bo Zhang, Zi Qian Sun, Hao Zhang, Wen Wang, Zi Ru Wang, Zhi Kai Guo, Shouyun Yu, Ren Xiang Tan, Hui Ming Ge
Publikováno v:
ACS Catalysis. 12:9839-9845
Publikováno v:
Journal of Natural Products. 85:1442-1447
Spirocitromycetin, an antiosteoporotic polyketide bearing a unique spirocycle, was characterized from a human mucus sputum-derived
In Vitro Reconstitution of Cinnamoyl Moiety Reveals Two Distinct Cyclases for Benzene Ring Formation
Autor:
Jing Shi, Yang Shi, Jian Cheng Li, Wanqing Wei, Yu Chen, Ping Cheng, Cheng Li Liu, Hao Zhang, Rui Wu, Bo Zhang, Rui Hua Jiao, Shouyun Yu, Yong Liang, Ren Xiang Tan, Hui Ming Ge
Publikováno v:
Journal of the American Chemical Society. 144:7939-7948
Autor:
Yu Meng Yang, Er Juan Zhao, Wanqing Wei, Zi Fei Xu, Jing Shi, Xuan Wu, Bo Zhang, Yasuhiro Igarashi, Rui Hua Jiao, Yong Liang, Ren Xiang Tan, Hui Ming Ge
Publikováno v:
Angewandte Chemie International Edition. 62
Lorneic acid and related natural products are featured by a trialkyl-substituted benzene rings. The formation of the aromatic core in the middle of polyketide chain is unusual. We characterized a cytochrome P450 enzyme that can catalyze the hallmark
Autor:
Ren-Xiang Tan, Rui-Hua Jiao, Jia-Qi Ma, Jing Shi, Hui Ming Ge, Bo Zhang, Yong-Chao Wang, Zi-Fei Xu
Publikováno v:
Chinese Chemical Letters. 33:511-515
Lanthipeptides are one of the largest groups of ribosomally synthesized and post-translationally modified peptides (RiPPs) and are characterized by the presence of lanthionine (Lan) or methyllanthionine residues (MeLan). Only very few lanthipeptides