Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hui Kheng, Lim"'
Autor:
Crompton, Rachel A., Williams, Helen, Campbell, Laura, Hui Kheng, Lim, Saville, Charis, Ansell, David M., Reid, Adam, Wong, Jason, Vardy, Leah A., Hardman, Matthew J., Cruickshank, Sheena M.
Publikováno v:
In Journal of Investigative Dermatology April 2022 142(4):1206-1216
Autor:
Christopher Owen Hughes, Hui Kheng Lim, Joseph Choon Wee Tan, David Ian Leavesley, Benjamin Paul Chapman Smith
Publikováno v:
Mutagenesis.
The aim of the present study was to evaluate the compatibility of reconstructed 3D human small intestinal microtissues to perform the in vitro comet assay. The comet assay is a common follow-up genotoxicity test to confirm or supplement other genotox
Autor:
Hui Kheng Lim, Christopher Owen Hughes, Michelle Jing Sin Lim, Jia’En Jasmine Li, Moumita Rakshit, Calvin Yeo, Kern Rei Chng, Angela Li, Joanne Sheot Harn Chan, Kee Woei Ng, David Ian Leavesley, Benjamin Paul Chapman Smith
The micronucleus (MN) assay is widely used as part of a battery of tests applied to evaluate the genotoxic potential of chemicals, including new food additives and novel food ingredients. Micronucleus assays typically utilise homogenous in vitro cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fee3ae10cb3bfc85b4cb683be7ed006
https://hdl.handle.net/10356/161945
https://hdl.handle.net/10356/161945
Autor:
Leah A. Vardy, Shatarupa Das, Kazuei Igarashi, Anisa Rahim, John E.A. Common, Takeshi Uemura, Hui Kheng Lim, Vonny I. Leo, Thiam Chye Lim
Publikováno v:
Journal of Investigative Dermatology. 138:2653-2665
Wound healing is a dynamic process involving gene-expression changes that drive re-epithelialization. Here, we describe an essential role for polyamine regulator AMD1 in driving cell migration at the wound edge. The polyamines, putrescine, spermidine
Autor:
Henry Yang, Leah A. Vardy, Thiam Chye Lim, Sophie Bellanger, Jonathan Hardman-Smart, Vonny I. Leo, Kazuei Igarashi, Anisa Rahim, Ralf Paus, Christina Yan Ru Tan, John E.A. Common, Takeshi Uemura, Hui Kheng Lim, Li Jia
Publikováno v:
Journal of Investigative Dermatology. 141:2178-2188.e6
Maintaining tissue homeostasis depends on a balance between cell proliferation, differentiation, and apoptosis. Within the epidermis, the levels of the polyamines putrescine, spermidine, and spermine are altered in many different skin conditions, yet
Autor:
Gurung, Resham Lal1,2, Hui Kheng Lim1, Venkatesan, Shriram1, Su Wen Lee, Phoebe1, Hande, M. Prakash1,3 phsmph@nus.edu.sg
Publikováno v:
Molecular Cancer. 10/13/2014, Vol. 13, p1-14. 14p. 1 Chart.
Publikováno v:
Molecular Cancer
Background Patients suffering from brain tumours such as glioblastoma and medulloblastoma have poor prognosis with a median survival of less than a year. Identifying alternative molecular targets would enable us to develop different therapeutic strat
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
Frontiers in Genetics
Frontiers in Genetics
Silver nanoparticles (Ag-np) have been used extensively in medicine and commercially due to their anti-microbial properties. Therapeutic potentials of these nanoparticles are being explored extensively despite the lack of information on their mechani
Autor:
P. V. Asharani, Swaminathan Sethu, Suresh Valiyaveettil, M. Prakash Hande, Ganapathy Balaji, Hui Kheng Lim
Publikováno v:
Genome Integrity
Background Investigating the cellular and molecular signatures in eukaryotic cells following exposure to nanoparticles will further our understanding on the mechanisms mediating nanoparticle induced effects. This study illustrates the molecular effec