Zobrazeno 1 - 10
of 390
pro vyhledávání: '"Hui Hua, Li"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-16 (2024)
Abstract The mitochondrial dynamic imbalance is an important cause of myocardial ischaemia/reperfusion (I/R) injury and dysfunction. Psmb8, as one of the immunoproteasome catalytic subunits, is a key regulator of protein homoeostasis, inflammation an
Externí odkaz:
https://doaj.org/article/c42f94fde93b42ac9f26e9046785c5cc
Autor:
Wen-Xi Jiang, Hui-Hua Li
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Sepsis is a life-threatening condition that is characterized by multiorgan dysfunction and caused by dysregulated cytokine networks, which are closely associated with sepsis progression and outcomes. However, currently available t
Externí odkaz:
https://doaj.org/article/bf46302cea154f4ebad4506e0d0ea3f1
Autor:
Shuai Wang, Jing Li, Jie Bai, Jing-Min Li, Yi-Lin Che, Qiu-Yue Lin, Yun-Long Zhang, Hui-Hua Li
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103181- (2024)
Externí odkaz:
https://doaj.org/article/3e97f4ccdf0544c58b18269bf0ab78cf
Publikováno v:
Pharmacological Research, Vol 204, Iss , Pp 107215- (2024)
The ubiquitinproteasome system (UPS) is the main mechanism responsible for the intracellular degradation of misfolded or damaged proteins. Under inflammatory conditions, the immunoproteasome, an isoform of the proteasome, can be induced, enhancing
Externí odkaz:
https://doaj.org/article/2760a308def24f1e8f06cd9d97cfa6ff
Publikováno v:
Journal of Advanced Research, Vol 55, Iss , Pp 17-31 (2024)
Introduction: Leukocyte infiltration is an early event during cardiac remodeling frequently leading to heart failure (HF). Integrins mediate leukocyte infiltration during inflammation. However, the importance of specific integrins in hypertensive car
Externí odkaz:
https://doaj.org/article/7aafa55c74064091b622395073220f65
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 103004- (2024)
Angiotensin converting enzyme 2 (ACE2) is a new identified member of the renin-angiotensin-aldosterone system (RAAS) that cleaves angiotensin II (Ang II) to Ang (1–7), which exerts anti-inflammatory and antioxidative activities via binding with Mas
Externí odkaz:
https://doaj.org/article/033d63e9f6064ed6a70b70f8dee2ad88
Autor:
Yi-Lin Ong, Xiao Deng, Hui-Hua Li, K. Narasimhalu, Ling-Ling Chan, Kumar M. Prakash, Wing-Lok Au, Pavanni Ratnagopal, Louis C.S. Tan, Eng-King Tan
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 40, Iss , Pp 100877- (2023)
Summary: Background: Caffeine intake reduces risk of Parkinson's disease (PD), but the interaction with genes is unclear. The interaction of caffeine with genetic variants in those at high PD risk has healthcare importance. We investigate interaction
Externí odkaz:
https://doaj.org/article/6eff82c6fc854e4fb8d09efc55a5ceb8
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 2, p 38 (2024)
Perioperative neurocognitive disorders (PND) are a cognitive impairment that occurs after anesthesia, especially in elderly patients and significantly affects their quality of life. The hippocampus, as a critical region for cognitive function and an
Externí odkaz:
https://doaj.org/article/d71261eec60e4bc9bbc9de53ca394c27
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Septic acute kidney injury (AKI) is the commonest cause of complication of sepsis in intensive care units, but its pathophysiology remains unclear. Calprotectin (S100A8/A9), which is a damage-associated molecular patterns (DAMPs) molecule, exerts a c
Externí odkaz:
https://doaj.org/article/41b115352e8b4ceca2e97a46a4bf1b20
Autor:
Yao-Chia Shih, Leon Qi Rong Ooi, Hui-Hua Li, John Carson Allen, Septian Hartono, Thomas Welton, Eng-King Tan, Ling Ling Chan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundDeep gray nuclear pathology relates to motor deterioration in idiopathic Parkinson’s disease (PD). Inconsistent deep nuclear diffusion tensor imaging (DTI) findings in cross-sectional or short-term longitudinal studies have been reported.
Externí odkaz:
https://doaj.org/article/e8fa6ceda10040d7a80aa9794274adbc