Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Hui Chang Bi"'
Autor:
Xiao-Long Jiang, Pan-Yue Luo, Yan-Ying Zhou, Zhi-Hui Luo, Yue-Jun Hao, Ming-Zhi Fan, Xiao-Han Wu, Hao Gao, Hui-Chang Bi, Zhi-Bin Zhao, Mei-Lan Lian, Zhe-Xiong Lian
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
O. elatus Nakai is a traditional medicine that has been confirmed to exert effective antioxidant and anti-inflammatory functions, and is used for the treatment of different disorders. However, its potential beneficial effects on drug induced hepatoto
Externí odkaz:
https://doaj.org/article/d8d4917ce09c4d73aaccafdcc49c2f19
Autor:
Liang Ding, Fang‐bin Zhang, Hui Liu, Xiang Gao, Hui‐chang Bi, Ling Huang, Xue‐ding Wang, Bai‐li Chen, Yu Zhang, Chuanzhu Lv, Pin‐jin Hu, Min Huang
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Xanthine oxidase (XO) competes with thiopurine S‐methyltransferase (TPMT) and hypoxanthine guanine phosphoribosyltransferase (HPRT) to metabolize azathioprine (AZA)/6‐mercaptopurine (6‐MP) in vivo. A retrospective investigation was per
Externí odkaz:
https://doaj.org/article/7cfd2e23b429416e9ffd23d0a1a6ef71
Autor:
Ya-Di Zhu, Xiao-Qing Guan, Jing Chen, Sheng Peng, Moshe Finel, Ying-Yuan Zhao, Rui-Min Wang, Hui-Chang Bi, Ming Lei, Dan-Dan Wang, Guang-Bo Ge
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
UDP-glucuronosyltransferase 1A1 (UGT1A1) is an essential enzyme in mammals that is responsible for detoxification and metabolic clearance of the endogenous toxin bilirubin and a variety of xenobiotics, including some crucial therapeutic drugs. Discov
Externí odkaz:
https://doaj.org/article/5a19f072ec1e4a7b8c798ddc099ca5f2
Publikováno v:
Chinese Journal of Chemistry. 40:2633-2641
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ade6fc03a0cf4e2d29f3e554c4a31c
https://doi.org/10.1002/cjoc.202200318
https://doi.org/10.1002/cjoc.202200318
Autor:
Dong, Huang, Ying-Yuan, Zhao, Rui-Min, Wang, Wei, Li, Fang-Yu, Yuan, Xue-Long, Yan, Xiao, Yang, Gui-Hua, Tang, Sheng, Yin, Hui-Chang, Bi
Publikováno v:
Acta Pharmacologica Sinica. 43:2139-2146
Cholestasis is a major cause of a series of bile flow malfunction-related liver diseases. Pregnane X receptor (PXR) is a key regulator in endo- and xeno-biotics metabolism, which has been considered as a promising therapeutic target for cholestasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d66ba965a31f51c103700bee19fcf4
https://doi.org/10.1038/s41401-021-00793-3
https://doi.org/10.1038/s41401-021-00793-3
Autor:
Tao Yu, Yong-Tao Wang, Pan Chen, Yu-Hua Li, Yi-Xin Chen, Hang Zeng, Ai-Ming Yu, Min Huang, Hui-Chang Bi
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 2, Pp 710-721 (2015)
Background: Aberrant expression of Nicotinamide N-methyltransferase (NNMT) has been reported in pancreatic cancer. However, the role of NNMT in pancreatic cancer development remains elusive. Therefore, the present study was to investigate the impact
Externí odkaz:
https://doaj.org/article/4a2ab5e2f77449a3a776026cc1982da9
Publikováno v:
Acta pharmacologica Sinica.
Pregnane X receptor (PXR) is highly expressed in the liver and plays a pivotal role in xenobiotic and endobiotic metabolism. We previously reported that PXR activation by its specific mouse agonist pregnenolone 16α-carbonitrile (PCN) significantly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb55b9f7d75ed64d79c28226383cc0c
https://pubmed.ncbi.nlm.nih.gov/35773338
https://pubmed.ncbi.nlm.nih.gov/35773338
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Green tea polyphenols (GTPs) have been shown to exhibit diverse beneficial effects against a variety of diseases. Acetaminophen (APAP) overdose is one of the most frequent causes of drug-induced liver injury. In the current study, we aimed to investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6393a0d55d4eabd82fff537e9006622
https://doi.org/10.1155/2020/2696432
https://doi.org/10.1155/2020/2696432
Autor:
Ruimin Wang, Fang-Yu Yuan, Yue-Hua Pan, Hui-Chang Bi, Gui-Hua Tang, Wei Li, Ying-Yuan Zhao, Sheng Yin, Dong Huang
Publikováno v:
Organic Letters. 22:4435-4439
Crotonpenoids A (1) and B (2), two highly modified clerodane diterpenoids featuring a new 10-(butan-2-yl)-1,6,12-trimethyltricyclo[7.2.1.02,7]dodecane skeleton, were isolated from the leaves and twigs of Croton yanhuii. Their structures including the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9742ac17c3e263e14ae66e99f29acdf5
https://doi.org/10.1021/acs.orglett.0c01443
https://doi.org/10.1021/acs.orglett.0c01443
Autor:
Quan-Fei Huang, Huizhen Zhang, Yixin Chen, Kai-Li Fu, Lihuan Guan, Jian-Bo Wan, Dong-Shun Li, Xi Li, Hui-Chang Bi, Min Huang
Publikováno v:
Chinese Journal of Natural Medicines. 18:211-218
Cholestasis is caused by the obstacle of bile formation or secretion and can develop into severe liver diseases. We previously reported the ethanol extract of Schisandra sphenanthera (Wuzhi tablet, WZ) can significantly protect against lithocholic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06a2fda4a2ef90af10bc995d9ed6911
https://doi.org/10.1016/s1875-5364(20)30023-6
https://doi.org/10.1016/s1875-5364(20)30023-6