Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hui B Sun"'
Autor:
Calogera M Simonaro, Sylvain Sachot, Yi Ge, Xingxuan He, Victor A Deangelis, Efrat Eliyahu, Daniel J Leong, Hui B Sun, Jeffrey B Mason, Mark E Haskins, Dean W Richardson, Edward H Schuchman
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62715 (2013)
Acid ceramidase is required to maintain the metabolic balance of several important bioactive lipids, including ceramide, sphingosine and sphingosine-1-phosphate. Here we show that addition of recombinant acid ceramidase (rAC) to primary chondrocyte c
Externí odkaz:
https://doaj.org/article/940af73a6bb0409b9315b0fd6ccc0445
Autor:
Jonathan Y Lee, Zuping Zhou, Peter J Taub, Melissa Ramcharan, Yonghui Li, Takintope Akinbiyi, Edward R Maharam, Daniel J Leong, Damien M Laudier, Takuya Ruike, Phillip J Torina, Mone Zaidi, Robert J Majeska, Mitchell B Schaffler, Evan L Flatow, Hui B Sun
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17531 (2011)
We characterized the differentiation of rat bone marrow-derived mesenchymal stem cells (BM-MSCs) into tenocyte-like cells in response to bone morphogenetic protein-12 (BMP-12). BM-MSCs were prepared from Sprague-Dawley rats and cultured as monolayers
Externí odkaz:
https://doaj.org/article/ae65fd77be85486589f50a62da92add4
Publikováno v:
Journal of Orthopaedic Translation, Vol 9, Iss C, Pp 69-75 (2017)
Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article
Externí odkaz:
https://doaj.org/article/15091df6a4f14b4d86543a85d9519a8b
Autor:
Shigeo M. TANAKA, Hui B. SUN
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 4, Iss 3, Pp 434-442 (2009)
The purpose of this study is to test a hypothesis that involvement of the low-magnitude, high frequency strain components in the walking-induced bone strain is essential to elicit the osteogenic response of osteoblasts to the bone strain. To this end
Externí odkaz:
https://doaj.org/article/fda36a631eae4793bba70880406b888f
Autor:
Angela Wang Ilaltdinov, Hui B. Sun, Yubao Gong, Daniel J. Leong, Konrad I. Gruson, Deyou Zheng, Li Sun, David T. Fung
Publikováno v:
Annals of the New York Academy of SciencesReferences. 1490(1)
Tendinopathy is a common musculoskeletal disorder characterized by chronic low-grade inflammation and tissue degeneration. Tendons have poor innate healing ability and there is currently no cure for tendinopathy. Studies elucidating mechanisms underl
Publikováno v:
Annals of the New York Academy of Sciences. 1410:57-67
Exosomes are nanovesicles secreted from cells that play key roles in intercellular communication. They carry unique content derived from parental cells and are capable of transferring this cargo between cells. The role and function of exosomes largel
Publikováno v:
Journal of Orthopaedic Translation, Vol 9, Iss C, Pp 69-75 (2017)
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation
Summary Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this
Autor:
Haotian, Feng, Zhiyong, He, Kristin, Twomey, Angela Wang, Ilaltdinov, Daniel, Leong, Yanhua, Wang, Jianmin, Li, David, Gonzalez, Hui B, Sun
Publikováno v:
Discovery medicine. 27(147)
Rotator cuff tendinopathy is one of the leading causes of shoulder pain. However, the mechanisms involved in the development of rotator cuff tendinopathy pain are not fully understood. In this study, we first examined the histological features of sub
Autor:
David M. Hirsh, Lin Xu, Daniel J. Leong, Robert J. Majeska, Sun J. Kim, Zhiyong He, Hui B. Sun, Mary B. Goldring, Neil J. Cobelli, Lidi Liu, Haotian Feng, Laijin Lu
Publikováno v:
Annals of the New York Academy of Sciences. 1442(1)
Adipokines secreted from the infrapatellar fat pad (IPFP), such as adipsin and adiponectin, have been implicated in osteoarthritis pathogenesis. CITED2, a mechanosensitive transcriptional regulator with chondroprotective activity, may modulate their