Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hui‐ling Gao"'
Autor:
Chao-Feng He, Shun-Hao Wang, Ying-Jie Yu, He-Yun Shen, Yan Zhao, Hui-Ling Gao, Hai Wang, Lin-Lin Li, Hui-Yu Liu
Publikováno v:
Cancer Biology & Medicine, Vol 13, Iss 3, Pp 299-312 (2016)
Photothermal cancer therapy is an alternative to chemotherapy, radiotherapy, and surgery. With the development of nanophotothermal agents, this therapy holds immense potential in clinical translation. However, the toxicity issues derived from the fac
Externí odkaz:
https://doaj.org/article/44a39d3a79f14b37b578ad28a7e90cb5
Autor:
Zhuo Wang, Ya-Hong Zhang, Chuang Guo, Hui-Ling Gao, Man-Li Zhong, Ting-Ting Huang, Na-Na Liu, Rui-Fang Guo, Tian Lan, Wei Zhang, Zhan-You Wang, Pu Zhao
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Although the positive relationship between copper and Alzheimer's disease (AD) was reported by a lot of epidemiological data, the mechanism is not completely known. Copper is a redox metal and serves as a mediator of inflammation. Because the homeost
Externí odkaz:
https://doaj.org/article/17ab3d6c1f1347d3a73fd11c1003b2eb
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 10, Iss 4, Pp 479-482 (2010)
Objective To construct a secretary eukaryotic expression plasmid for chondroitinase ABCⅠ, and observe the expression of the target protein in a glioma cell line TJ905. Methods The DNA fragments encoding the signal peptide of basilar membrane 40 (BM
Externí odkaz:
https://doaj.org/article/53592518cc9d4955b17c5d49f38df3a1
Autor:
Hui-Ling Gao, Cheng Li, Hiroaki Nabeka, Tetsuya Shimokawa, Naoto Kobayashi, Shouichiro Saito, Zhan-You Wang, Ya-Ming Cao, Seiji Matsuda
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80032 (2013)
BackgroundDuchenne muscular dystrophy caused by a mutation in the X-linked dystrophin gene induces metabolic and structural disorders in the brain. A lack of dystrophin in brain structures is involved in impaired cognitive function. Prosaposin (PS),
Externí odkaz:
https://doaj.org/article/96823caf46bf4d69a2bcfe3f92f0c223
Autor:
Ying-Ying Yang, Yan-Tao Ren, Meng-Yu Jia, Chen-Yang Bai, Xiu-Ting Liang, Hui-Ling Gao, Man-Li Zhong, Tao Wang, Chuang Guo
Publikováno v:
Experimental Neurology. 362:114346
Autor:
Lin-Bo, Li, Yong-Gang, Fan, Wen-Xi, Wu, Chen-Yang, Bai, Meng-Yu, Jia, Jiang-Ping, Hu, Hui-Ling, Gao, Tao, Wang, Man-Li, Zhong, Xue-Shi, Huang, Chuang, Guo
Publikováno v:
Bioorganic Chemistry. 128:106100
Researchers continue to explore drug targets to treat the characteristic pathologies of Alzheimer's disease (AD). Some drugs relieve the pathological processes of AD to some extent, but the failed clinical trials indicate that multifunctional agents
Autor:
Xiaoyu Zhang, You Li, Hui-Ling Gao, Pu Zhao, Chuang Guo, Man-Li Zhong, He Xu, Xiancheng Zhang, Tao Wang
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6842, p 6842 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6842, p 6842 (2021)
Copper (Cu) has been implicated in the progression of Alzheimer’s disease (AD), and aggregation of Cu and amyloid β peptide (Aβ) are considered key pathological features of AD. Metal chelators are considered to be potential therapeutic agents for
Autor:
Hejia Kou, Hui-Ling Gao, Pu Zhao, Tao Wang, Xiaoyu Zhang, Wang Lan, Wei Zheng, Man-Li Zhong, Feng Guo, Chuang Guo, Zhan-You Wang, He Xu
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 13 (2021)
Frontiers in Aging Neuroscience, Vol 13 (2021)
Alzheimer’s disease (AD) is a type of neurodegenerative disease that is associated with the accumulation of amyloid plaques. Increasing non-amyloidogenic processing and/or manipulating amyloid precursor protein signaling could reduce AD amyloid pat
Autor:
Hui-Ling Gao, Tian Guo, Yu-Han Meng, Chuang Guo, Yan-Hong Chen, Wei Zhang, Di Wang, Wen-Qiang Xuan, Pu Zhao, Yan-Tao Ren, Han Xue
Publikováno v:
Foodfunction. 11(8)
Lactoferrin (Lf), an iron-binding glycoprotein, has been shown to possess antioxidant and anti-inflammatory properties and exert modulatory effects on lipid homeostasis and non-alcoholic fatty liver disease (NAFLD), but our understanding of its regul
Autor:
Zhan-You Wang, Hui-Ling Gao, Pu Zhao, Man-Li Zhong, You Li, Jia Sun, Wang Lan, Hehong Sun, Xiaoyu Zhang, Xuliang Wang, Xiancheng Zhang
Publikováno v:
Biomaterials Science. 7:5197-5210
Zn2+ has been implicated in the progression of Alzheimer's disease (AD), as amyloid-β protein (Aβ) aggregation and neurotoxicity are mediated by zinc ions. Therefore, development of metal chelators for inhibiting and regulating metal-triggered Aβ