Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Hui‐juan Jin"'
Autor:
Hui-Juan Jin, Yong Fan, Xiaoyu Yang, Yue Dong, Xiao-Zhen Zhang, Xin-Yan Geng, Zheng Yan, Ling Wu, Meng Ma, Bin Li, Qifeng Lyu, Yun Pan, Mingxi Liu, Yanping Kuang, Su-Ren Chen
Publikováno v:
eLife, Vol 13 (2024)
The perinuclear theca (PT) is a dense cytoplasmic web encapsulating the sperm nucleus. The physiological roles of PT in sperm biology and the clinical relevance of variants of PT proteins to male infertility are still largely unknown. We reveal that
Externí odkaz:
https://doaj.org/article/9674fc92cbdb446f88492f9ce032c564
Publikováno v:
eLife, Vol 12 (2023)
Male infertility is a worldwide population health concern. Asthenoteratozoospermia is a common cause of male infertility, but its etiology remains incompletely understood. No evidence indicates the relevance of CFAP52 mutations to human male infertil
Externí odkaz:
https://doaj.org/article/b397bd39a88644a9af4e3fff2328f758
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104675- (2023)
Summary: Background: Male infertility is a worldwide population health concern, but its aetiology remains largely understood. Although CFAP70 variants have already been reported in two oligo-astheno-teratozoospermia (OAT) individuals by sequencing, a
Externí odkaz:
https://doaj.org/article/21afe3d4489243e3ac9ad370de83cdc9
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111049- (2022)
Summary: The perinuclear theca (PT) is a cytoskeletal element encapsulating the sperm nucleus; however, our understanding of the physiological roles of PT in sperm is very limited. We show that Calicin interacts with itself and many other PT componen
Externí odkaz:
https://doaj.org/article/658885bc3064458aba1a69a5b47126f5
Autor:
Jie‐hong Wu, Ya‐nan Li, An‐qi Chen, Can‐dong Hong, Chun‐lin Zhang, Hai‐ling Wang, Yi‐fan Zhou, Peng‐Cheng Li, Yong Wang, Ling Mao, Yuan‐peng Xia, Quan‐wei He, Hui‐juan Jin, Zhen‐yu Yue, Bo Hu
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 2, Pp 1-23 (2020)
Abstract Diabetic retinopathy (DR) is a common complication of diabetes and leads to blindness. Anti‐VEGF is a primary treatment for DR. Its therapeutic effect is limited in non‐ or poor responders despite frequent injections. By performing a com
Externí odkaz:
https://doaj.org/article/14c29eb98628469881203dfdcc387171
Autor:
Jie-hong Wu, Yi-fan Zhou, Can-dong Hong, An-qi Chen, Yan Luo, Ling Mao, Yuan-peng Xia, Quan-wei He, Hui-juan Jin, Ming Huang, Ya-nan Li, Bo Hu
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 95-108 (2019)
Background: Neointimal hyperplasia is a prominent pathological event during in-stent restenosis. Phenotype switching of vascular smooth muscle cells (VSMCs) from a differentiated/contractile to a dedifferentiated/synthetic phenotype, accompanied by m
Externí odkaz:
https://doaj.org/article/b910d77da7b84e63a8306908a7554d53
Publikováno v:
Development. 149
The perinuclear theca (PT) is a cytoskeletal element encapsulating the sperm nucleus; however, the physiological roles of the PT in sperm are largely uncertain. Here, we reveal that ACTRT1, ACTRT2, ACTL7A and ACTL9 proteins interact to form a multime
Publikováno v:
Cell reports. 40(1)
The perinuclear theca (PT) is a cytoskeletal element encapsulating the sperm nucleus; however, our understanding of the physiological roles of PT in sperm is very limited. We show that Calicin interacts with itself and many other PT components, indic
Publikováno v:
The FASEB Journal. 32:2181-2196
The inflammatory process in stroke is the major contributor to blood-brain barrier (BBB) breakdown. Previous studies indicated that semaphorin 4D (Sema4D), an axon guidance molecule, initiated inflammatory microglial activation and disrupted endothel