Zobrazeno 1 - 10
of 966
pro vyhledávání: '"Huhtaniemi, P"'
Autor:
Ewelina Palak, Donata Ponikwicka-Tyszko, Kamila Pulawska-Moon, Maria Sztachelska, Gabriela Milewska, Beata Modzelewska, Tomasz Kleszczewski, Maria L. Koivukoski, Piotr Bernaczyk, Hady Razak Hady, Piotr Gołaszewski, Aleksandra N. Lupinska, Marek Kulikowski, Adam Lemancewicz, Ilpo T. Huhtaniemi, Slawomir Wolczynski, Nafis A. Rahman
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background Extragonadal follicle-stimulating hormone receptor (FSHR) expression at low levels has been shown in several normal and tumor tissues, including myometrium and adipose tissue. FSH-FSHR signaling in the myometrium has been suggeste
Externí odkaz:
https://doaj.org/article/5c80b4d0eb8546c99d303e9832118381
Autor:
Ravinder Anand-Ivell, Kee Heng, Leen Antonio, Gyorgy Bartfai, Felipe F. Casanueva, Mario Maggi, Terence W. O’Neill, Margus Punab, Giulia Rastrelli, Jolanta Slowikowska-Hilczer, Jos Tournoy, Dirk Vanderschueren, Frederick CW. Wu, Ilpo T. Huhtaniemi, Richard Ivell
Publikováno v:
The Aging Male, Vol 27, Iss 1 (2024)
Insulin-like peptide 3 (INSL3) is a circulating biomarker for Leydig cell functional capacity in men, also indicating Leydig Cell Insufficiency (LCI) and potential primary hypogonadism. Using results from large cohort studies we explore sources of bi
Externí odkaz:
https://doaj.org/article/f078b0006c6046e2b1a396c779d2c83f
Autor:
Seema D. Sharma, Michael J. Cook, Leen Antonio, Evelien Gielen, Gyorgy Bartfai, Felipe F. Casanueva, Ilpo T. Huhtaniemi, Mario Maggi, Margus Punab, Giulia Rastrelli, Jolanta Slowikowska-Hilczer, Jos Tournoy, Dirk Vanderschueren, Frederick C. Wu, Terence W. O’Neill
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Previous studies have suggested an association between sleep disturbance and frailty. The mechanism is unknown, although it has been suggested that hormonal factors may play a role. Methods The aim was to determine the association
Externí odkaz:
https://doaj.org/article/325d43a6b453497192433e12ffa4edf3
Autor:
Oxana V. Denisova, Joni Merisaari, Riikka Huhtaniemi, Xi Qiao, Laxman Yetukuri, Mikael Jumppanen, Amanpreet Kaur, Mirva Pääkkönen, Сarina vonSchantz‐Fant, Michael Ohlmeyer, Krister Wennerberg, Otto Kauko, Raphael Koch, Tero Aittokallio, Mikko Taipale, Jukka Westermarck
Publikováno v:
Molecular Oncology, Vol 17, Iss 9, Pp 1803-1820 (2023)
Mitochondrial glycolysis and hyperactivity of the phosphatidylinositol 3‐kinase–protein kinase B (AKT) pathway are hallmarks of malignant brain tumors. However, kinase inhibitors targeting AKT (AKTi) or the glycolysis master regulator pyruvate de
Externí odkaz:
https://doaj.org/article/a2e1d31113f04fc1a661ea35069e7372
Autor:
Verneri Virtanen, Kreetta Paunu, Antti Kukkula, Saana Niva, Ylva Junila, Mervi Toriseva, Terhi Jokilehto, Sari Mäkelä, Riikka Huhtaniemi, Matti Poutanen, Ilkka Paatero, Maria Sundvall
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-12 (2023)
Abstract Lethal prostate cancer (PCa) is characterized by the presence of metastases and development of resistance to therapies. Metastases form in a multi-step process enabled by dynamic cytoskeleton remodeling. An actin cytoskeleton regulating gene
Externí odkaz:
https://doaj.org/article/bc81cdeac0e2439e9c19b849d1d94729
Akademický článek
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Akademický článek
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Autor:
Nadjia Amini, Jolan Dupont, Laurence Lapauw, Laura Vercauteren, Leen Antonio, Terence W. O'Neill, Dirk Vanderschueren, Neil Pendleton, Giulia Rastrelli, Mario Maggi, Felipe F. Casanueva, Jolanta Słowikowska‐Hilczer, Margus Punab, Ilpo T. Huhtaniemi, Frederick C.W. Wu, Sabine Verschueren, Jos Tournoy, Evelien Gielen
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1520-1532 (2023)
Abstract Background Previous research suggests that sarcopenia is associated with lower cognitive functioning. Evidence on the longitudinal relationship between cognition and sarcopenia, according to the revised criteria of the European Working Group
Externí odkaz:
https://doaj.org/article/2ca32f3b587a4034b55ba734a3f31de4
Autor:
Iman J. Schultz, Yvette Zimmerman, Cathy B. Moelans, Marcin Chrusciel, Jan Krijgh, Paul J. van Diest, Ilpo T. Huhtaniemi, Herjan J. T. Coelingh Bennink
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundExpression of Zona Pellucida glycoprotein 3 (ZP3) in healthy tissue is restricted to the extracellular Zona Pellucida layer surrounding oocytes of ovarian follicles and to specific cells of the spermatogenic lineage. Ectopic expression of Z
Externí odkaz:
https://doaj.org/article/8ee16e995e5c4eb683f816de22705973
Autor:
Karolina Pavic, Nikhil Gupta, Judit Domènech Omella, Rita Derua, Anna Aakula, Riikka Huhtaniemi, Juha A. Määttä, Nico Höfflin, Juha Okkeri, Zhizhi Wang, Otto Kauko, Roosa Varjus, Henrik Honkanen, Daniel Abankwa, Maja Köhn, Vesa P. Hytönen, Wenqing Xu, Jakob Nilsson, Rebecca Page, Veerle Janssens, Alexander Leitner, Jukka Westermarck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Tumour suppressors are inhibited in cancers and their reactivation could provide novel therapy opportunities. Here, the authors study the structural mechanism by which human tumour suppressor Protein Phosphatase 2A is inhibited in breast cancer cells
Externí odkaz:
https://doaj.org/article/a40d0289287e4365ac202e20daf82ec2