Výsledky vyhledávání - "Hugues Thiebot"

The Expression of P-Glycoprotein and Cellular Kinases Is Modulated at the Transcriptional Level by Infection and Highly Active Antiretroviral Therapy in a Primate Model of AIDS

Autor: Nathalie Dereuddre-Bosquet, Dominique Dormont, Bruno Vaslin, Kadija Benlhassan-Chahour, Pascal Clayette, Roger Le Grand, Hugues Thiebot, Sylvie Jorajuria

Publikováno v: AIDS Research and Human Retroviruses. 19:307-311

The beneficial effects of highly active antiretroviral therapy (HAART) in HIV-infected patients may be limited by inadequate compliance and viral resistance, but also by host cell factors, such as P-glycoprotein (P-gp) and intracellular kinases invol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9163c8da994149b9738c6cfc9e606d
https://doi.org/10.1089/088922203764969500

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Retroviral interleukin 1α gene transfer in bone marrow stromal cells in a primate model: induction of myelopoiesis stimulation

Autor: Hugues Thiebot, Magid Methali, Thierry de Revel, Jean Philippe Spano, Nicolas Becard, Gabriel Gras, Sandrine Rousseau, Tania Sorg, Dominique Dormont, Roger Le Grand

Publikováno v: British Journal of Haematology. 118:875-884

Summary. Effects of interleukin 1-α (IL-1α), a proinflammatory cytokine with pleiotropic activity, in the myelopoietic setting, is mainly linked to its ability to increase haematopoietic growth factor production by bone marrow stromal cells. In ord

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf03b02f325f8850f11de768970a924c
https://doi.org/10.1046/j.1365-2141.2002.03672.x

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Early and Persistent Bone Marrow Hematopoiesis Defect in Simian/Human Immunodeficiency Virus-Infected Macaques despite Efficient Reduction of Viremia by Highly Active Antiretroviral Therapy during Primary Infection

Autor: Jérome Larghero, Olivier Neildez, Fawzia Louache, Roger Le Grand, Thierry de Revel, Hugues Thiebot, Bruno Vaslin, William Vainchenker, Dominique Dormont

Publikováno v: Journal of Virology. 75:11594-11602

The hematological abnormalities observed in human immunodeficiency virus (HIV)-infected patients appear to be mainly due to bone marrow dysfunction. A macaque models of AIDS could greatly facilitate an in vivo approach to the pathogenesis of such dys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7369e31a75a50e3b7b836010e11095e9
https://doi.org/10.1128/jvi.75.23.11594-11602.2001

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Post-exposure prophylaxis with highly active antiretroviral therapy could not protect macaques from infection with SIV/HIV chimera

Autor: Pascal Clayette, Pierre Sellier, Dominique Dormont, O Neidez, Hugues Thiebot, R. Le Grand, Bruno Vaslin, Jérôme Larghero, N Dereuddre-Bosquet

Publikováno v: AIDS. 14:1864-1866

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b9368900faa919f4def18e6dce74fd
https://doi.org/10.1097/00002030-200008180-00029

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Impact of bone marrow hematopoiesis failure on T-cell generation during pathogenic simian immunodeficiency virus infection in macaques

Autor: Bruno Vaslin, Sonia Derdouch, Jean-Marc Bertho, Dominique Dormont, Hugues Thiebot, Roger Le Grand, Stéphane Prost, Franck Mouthon, Pierre Ducouret, Gabriel Gras

Publikováno v: Blood. 105(6)

Experimental infection of macaques with pathogenic strains of simian immunodeficiency virus (SIV) represents one of the most relevant animal models for studying HIV pathogenesis. In this study, we demonstrated a significant decrease in the generation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bab09c19f5468285dc4294a569967f1
https://pubmed.ncbi.nlm.nih.gov/15388577

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Retroviral interleukin 1alpha gene transfer in bone marrow stromal cells in a primate model: induction of myelopoiesis stimulation

Autor: Thierry, de Revel, Nicolas, Becard, Tania, Sorg, Sandrine, Rousseau, Jean Philippe, Spano, Hugues, Thiebot, Magid, Methali, Gabriel, Gras, Roger, Le Grand, Dominique, Dormont

Publikováno v: British journal of haematology. 118(3)

Effects of interleukin 1-alpha (IL-1alpha), a proinflammatory cytokine with pleiotropic activity, in the myelopoietic setting, is mainly linked to its ability to increase haematopoietic growth factor production by bone marrow stromal cells. In order

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08d1d590016618dd5d79fab8acfe5c69
https://pubmed.ncbi.nlm.nih.gov/12181061

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Longitudinal analysis of CD8(+) T-cell phenotype and IL-7, IL-15 and IL-16 mRNA expression in different tissues during primary simian immunodeficiency virus infection

Autor: Hugues Thiebot, Bertrand Boson, Arnaud Chéret, Frédéric Théodoro, O. Neildez, P Caufour, Dominique Dormont, Bruno Vaslin, Roger Le Grand, Alain Venet

Publikováno v: Microbes and infection. 3(3)

Infection of macaques with pathogenic isolates of simian immunodeficiency virus (SIV) represents a useful model of HIV infection that offers the unique opportunity to investigate the very early modifications that affect CD8(+) T-lymphocyte subsets an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3944d0552a3eeca635b97b5d8547cbd
https://pubmed.ncbi.nlm.nih.gov/11358712

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114 Effects in macaques of SHIV infection and HAART on the expression of P-gp and cellular kinases

Autor: Pierre Sellier, R Le Grand, Bertrand Boson, Dominique Dormont, Jérôme Larghero, S. Jorajuria, Bruno Vaslin, N Dereuddre-Bosquet, Pascal Clayette, Hugues Thiebot, O. Neildez

Publikováno v: Antiviral Research. 46:A70

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c2b5ad008f3f207177b2541449aefc9
https://doi.org/10.1016/s0166-3542(00)90445-5

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