Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hugo Vigerelli"'
Autor:
Emidio Beraldo-Neto, Vanessa Florentino Ferreira, Hugo Vigerelli, Karolina Rosa Fernandes, Maria Aparecida Juliano, Ana Leonor Abrahao Nencioni, Daniel Carvalho Pimenta
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Voltage-gated potassium channels play a crucial role in cellular repolarization and are potential therapeutic targets in neuroinflammatory disorders and neurodegenerative diseases. This study explores Tityus bahiensis scorpion venom for neur
Externí odkaz:
https://doaj.org/article/eac4aad6622643c6aa934bf54d3b59b0
Autor:
Amanda Gomes da Silva, Mariana da Mata Alves, Admilson Aparecido da Cunha, Giovanna Arruda Caires, Irina Kerkis, Hugo Vigerelli, Juliana Mozer Sciani
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 29 (2023)
Abstract Background: Echinometra lucunter is a sea urchin commonly found on America’s rocky shores. Its coelomic fluid contains molecules used for defense and biological processes, which may have therapeutic potential for the treatment of amyloid-b
Externí odkaz:
https://doaj.org/article/e29933ae740d4383bf68984a169ab097
Autor:
Vitor Rodrigues da Costa, Olívia Fonseca Souza, Michelli Ramires Teixeira, Anderson Lucas Alievi, Hugo Vigerelli, Rodrigo Pinheiro Araldi
Publikováno v:
Exploration of Immunology, Vol 3, Iss 2, Pp 70-81 (2023)
Lung cancer is the leading cause of cancer-related deaths worldwide. The main risk factor for lung cancer is exposure to chemicals present in cigarettes and atmospheric pollutants, which, among other mechanisms, can increase the risk of cancer by ind
Externí odkaz:
https://doaj.org/article/2dda00aaf4a043d2ac6ad84666c1a5fe
Autor:
Daiane Laise da Silva, Rodrigo Valladão, Emidio Beraldo-Neto, Guilherme Rabelo Coelho, Oscar Bento da Silva Neto, Hugo Vigerelli, Adriana Rios Lopes, Brett R. Hamilton, Eivind A. B. Undheim, Juliana Mozer Sciani, Daniel Carvalho Pimenta
Publikováno v:
Marine Drugs, Vol 21, Iss 9, p 481 (2023)
Sea anemones are known to produce a diverse array of toxins with different cysteine-rich peptide scaffolds in their venoms. The serine peptidase inhibitors, specifically Kunitz inhibitors, are an important toxin family that is believed to function as
Externí odkaz:
https://doaj.org/article/347b74902ff947a2b73b70cd05de9186
Autor:
Rodrigo Pinheiro Araldi, Benedito Carlos Prezoto, Vivian Gonzaga, Bruna Policiquio, Thais Biude Mendes, Fernanda D’Amélio, Hugo Vigerelli, Mariana Viana, Cristiane Wenceslau Valverde, Eduardo Pagani, Irina Kerkis
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112920- (2022)
Since the COVID-19 pandemic started, mesenchymal stromal cells (MSC) appeared as a therapeutic option to reduce the over-activated inflammatory response and promote recovery of lung damage. Most clinical studies use intravenous injection for MSC deli
Externí odkaz:
https://doaj.org/article/d8710a474ce049c39b71e96c709f3797
Autor:
Bruna De Lucca Caetano, Marta de Oliveira Domingos, Miriam Aparecida da Silva, Jessika Cristina Alves da Silva, Juliana Moutinho Polatto, Fabio Montoni, Leo Kei Iwai, Daniel Carvalho Pimenta, Hugo Vigerelli, Paulo Cesar Gomes Vieira, Rita de Cassia Ruiz, José Salvatore Patané, Roxane Maria Fontes Piazza
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 172 (2022)
The secretion of α-hemolysin by uropathogenic Escherichia coli (UPEC) is commonly associated with the severity of urinary tract infections, which makes it a predictor of poor prognosis among patients. Accordingly, this toxin has become a target for
Externí odkaz:
https://doaj.org/article/b912a1ea23ec4e58989250fe3617b024
Autor:
Guilherme Rabelo Coelho, Daiane Laise da Silva, Emidio Beraldo-Neto, Hugo Vigerelli, Laudiceia Alves de Oliveira, Juliana Mozer Sciani, Daniel Carvalho Pimenta
Publikováno v:
Toxins, Vol 13, Iss 12, p 851 (2021)
Among the vast repertoire of animal toxins and venoms selected by nature and evolution, mankind opted to devote its scientific attention—during the last century—to a restricted group of animals, leaving a myriad of toxic creatures aside. There ar
Externí odkaz:
https://doaj.org/article/285bd6c1438b4999a29680c2bdc05740
Autor:
Vitor Rodrigues da Costa, Rodrigo Pinheiro Araldi, Hugo Vigerelli, Fernanda D’Ámelio, Thais Biude Mendes, Vivian Gonzaga, Bruna Policíquio, Gabriel Avelar Colozza-Gama, Cristiane Wenceslau Valverde, Irina Kerkis
Publikováno v:
Cells, Vol 10, Iss 10, p 2617 (2021)
Cancer is one of the most important health problems and the second leading cause of death worldwide. Despite the advances in oncology, cancer heterogeneity remains challenging to therapeutics. This is because the exosome-mediated crosstalk between ca
Externí odkaz:
https://doaj.org/article/6401885d224149c8b06e22f647530a65
Autor:
Fernanda D’Amélio, Hugo Vigerelli, Álvaro Rossan de Brandão Prieto-da-Silva, Eduardo Osório Frare, Isabel de Fátima Correia Batista, Daniel Carvalho Pimenta, Irina Kerkis
Publikováno v:
Toxins, Vol 13, Iss 7, p 459 (2021)
Osteoclasts (OCs) are important for bone maintenance, calcium balance, and tissue regeneration regulation and are involved in different inflammatory diseases. Our study aimed to evaluate the effect of Bothrops moojeni’s venom and its low and high m
Externí odkaz:
https://doaj.org/article/6b3206f2d8f44584ba1ebb4f6fd69a17
Autor:
Viviane Soares Souza Lima, Douglas Oscar Ceolin Mariano, Hugo Vigerelli, Sabrina Cardoso Janussi, Thayz Vanalli Lima Baptista, Mário Angelo Claudino, Daniel Carvalho Pimenta, Juliana Mozer Sciani
Publikováno v:
Molecules, Vol 26, Iss 10, p 2845 (2021)
Kynurenic acid (KYNA) is derived from tryptophan, formed by the kynurenic pathway. KYNA is being widely studied as a biomarker for neurological and cardiovascular diseases, as it is found in ischemic conditions as a protective agent; however, little
Externí odkaz:
https://doaj.org/article/c7d1b1797a5e4ea28dc6d7901eddbd5e