Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Hugo Varet"'
Autor:
Francesco Coppolino, Giuseppe Valerio De Gaetano, Cosme Claverie, Odile Sismeiro, Hugo Varet, Rachel Legendre, Angelica Pellegrini, Alessia Berbiglia, Luca Tavella, Germana Lentini, Agata Famà, Giulia Barbieri, Giampiero Pietrocola, Giuseppe Teti, Arnaud Firon, Concetta Beninati
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Group B Streptococcus (GBS) is a pathobiont responsible for invasive infections in neonates and the elderly. The transition from a commensal to an invasive pathogen relies on the timely regulation of virulence factors. In this study, we char
Externí odkaz:
https://doaj.org/article/a051552e92534d0cad659bc8d5ff50a6
Autor:
Markéta Harazim, Juliette Perrot, Hugo Varet, Hervé Bourhy, Julien Lannoy, Jiri Pikula, Veronika Seidlová, Laurent Dacheux, Natália Martínková
Publikováno v:
BMC Immunology, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Coevolution between pathogens and their hosts decreases host morbidity and mortality. Bats host and can tolerate viruses which can be lethal to other vertebrate orders, including humans. Bat adaptations to infection include locali
Externí odkaz:
https://doaj.org/article/c61ecd7490b64ab7afea726187f432b3
Autor:
Raffael Júnio Araújo de Castro, Clara Luna Marina, Aude Sturny-Leclère, Christian Hoffmann, Pedro Henrique Bürgel, Sarah Sze Wah Wong, Vishukumar Aimanianda, Hugo Varet, Ruchi Agrawal, Anamélia Lorenzetti Bocca, Alexandre Alanio
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011841 (2023)
Macrophages play a key role in disseminated cryptococcosis, a deadly fungal disease caused by Cryptococcus neoformans. This opportunistic infection can arise following the reactivation of a poorly characterized latent infection attributed to dormant
Externí odkaz:
https://doaj.org/article/8451a509f1124967828dec79d6589389
Autor:
Ewa Pasquereau-Kotula, Laurence du Merle, Odile Sismeiro, Natalia Pietrosemoli, Hugo Varet, Rachel Legendre, Patrick Trieu-Cuot, Shaynoor Dramsi
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294868 (2023)
Streptococcus gallolyticus sp. gallolyticus (SGG) is a gut pathobiont involved in the development of colorectal cancer (CRC). To decipher SGG contribution in tumor initiation and/or acceleration respectively, a global transcriptome was performed in h
Externí odkaz:
https://doaj.org/article/d73babfc16234fe9a759b8c299de853f
Autor:
Marie Robbe-Saule, Mélanie Foulon, Isabelle Poncin, Lucille Esnault, Hugo Varet, Rachel Legendre, Alban Besnard, Anna E. Grzegorzewicz, Mary Jackson, Stéphane Canaan, Laurent Marsollier, Estelle Marion
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1438-1451 (2021)
Mycobacterium ulcerans is the causal agent of Buruli ulcer, a chronic infectious disease and the third most common mycobacterial disease worldwide. Without early treatment, M. ulcerans provokes massive skin ulcers, caused by the mycolactone toxin, it
Externí odkaz:
https://doaj.org/article/1cb69814d64d40b389c32a0800f06a86
Autor:
Nicolas Vabret, Valérie Najburg, Alexander Solovyov, Ramya Gopal, Christopher McClain, Petr Šulc, Sreekumar Balan, Yannis Rahou, Guillaume Beauclair, Maxime Chazal, Hugo Varet, Rachel Legendre, Odile Sismeiro, Raul Y. Sanchez David, Lise Chauveau, Nolwenn Jouvenet, Martin Markowitz, Sylvie van der Werf, Olivier Schwartz, Frédéric Tangy, Nina Bhardwaj, Benjamin D. Greenbaum, Anastassia V. Komarova
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104599- (2022)
Summary: Pattern recognition receptors (PRRs) protect against microbial invasion by detecting specific molecular patterns found in pathogens and initiating an immune response. Although microbial-derived PRR ligands have been extensively characterized
Externí odkaz:
https://doaj.org/article/3f866d774d69450aaefc5a05b8e28df1
Autor:
Nicolas Huot, Philippe Rascle, Caroline Petitdemange, Vanessa Contreras, Christina M. Stürzel, Eduard Baquero, Justin L. Harper, Caroline Passaes, Rachel Legendre, Hugo Varet, Yoann Madec, Ulrike Sauermann, Christiane Stahl-Hennig, Jacob Nattermann, Asier Saez-Cirion, Roger Le Grand, R. Keith Reeves, Mirko Paiardini, Frank Kirchhoff, Beatrice Jacquelin, Michaela Müller-Trutwin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
NK cells control SIV infection in secondary lymphoid tissues in the natural host that typically doesn’t progress toward disease. Here the authors show that this control is associated with terminal NK cell differentiation and improved MHC-E-dependen
Externí odkaz:
https://doaj.org/article/7c09c41f3ce44f41931d8a99a69c119f
Autor:
Laura Piel, K Shanmugha Rajan, Giovanni Bussotti, Hugo Varet, Rachel Legendre, Caroline Proux, Thibaut Douché, Quentin Giai-Gianetto, Thibault Chaze, Thomas Cokelaer, Barbora Vojtkova, Nadav Gordon-Bar, Tirza Doniger, Smadar Cohen-Chalamish, Praveenkumar Rengaraj, Céline Besse, Anne Boland, Jovana Sadlova, Jean-François Deleuze, Mariette Matondo, Ron Unger, Petr Volf, Shulamit Michaeli, Pascale Pescher, Gerald F Späth
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010375 (2022)
The protozoan parasite Leishmania donovani causes fatal human visceral leishmaniasis in absence of treatment. Genome instability has been recognized as a driver in Leishmania fitness gain in response to environmental change or chemotherapy. How genom
Externí odkaz:
https://doaj.org/article/6054875378b740aabcc0a4e834d05c3b
Autor:
Frédéric Peyrusson, Hugo Varet, Tiep Khac Nguyen, Rachel Legendre, Odile Sismeiro, Jean-Yves Coppée, Christiane Wolz, Tanel Tenson, Françoise Van Bambeke
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Bacterial persister cells exhibit a transient non-growing state and antibiotic tolerance. Here, Peyrusson et al. provide evidence of metabolically active Staphylococcus aureus persisters within infected host cells exposed to antibiotics and analyse t
Externí odkaz:
https://doaj.org/article/7eb67a09da404cf28987ee6ac2709134
Autor:
Alfonso Soler-Bistué, Sebastián Aguilar-Pierlé, Marc Garcia-Garcerá, Marie-Eve Val, Odile Sismeiro, Hugo Varet, Rodrigo Sieira, Evelyne Krin, Ole Skovgaard, Diego J. Comerci, Eduardo P. C. Rocha, Didier Mazel
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background In fast-growing bacteria, the genomic location of ribosomal protein (RP) genes is biased towards the replication origin (oriC). This trait allows optimizing their expression during exponential phase since oriC neighboring regions
Externí odkaz:
https://doaj.org/article/0e46f0997c7e457d9ba2526935b7d3fc