Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Hugo Vankelecom"'
Autor:
Xavier Santamaria, Beatriz Roson, Raul Perez-Moraga, Nandakumar Venkatesan, Maria Pardo-Figuerez, Javier Gonzalez-Fernandez, Jaime Llera-Oyola, Estefania Fernández, Inmaculada Moreno, Andres Salumets, Hugo Vankelecom, Felipe Vilella, Carlos Simon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Asherman’s Syndrome is characterized by intrauterine adhesions or scarring, which cause infertility, menstrual abnormalities, and recurrent pregnancy loss. The pathophysiology of this syndrome remains unknown, with treatment restricted to
Externí odkaz:
https://doaj.org/article/8fa3b1cc9bb8431199e1f86b32d61d2b
Autor:
Aurélie Hennes, Johanna Devroe, Katrien De Clercq, Martina Ciprietti, Katharina Held, Katrien Luyten, Nele Van Ranst, Nina Maenhoudt, Karen Peeraer, Hugo Vankelecom, Thomas Voets, Joris Vriens
Publikováno v:
Reproductive Biology and Endocrinology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Early embryo implantation is a complex phenomenon characterized by the presence of an implantation-competent blastocyst and a receptive endometrium. Embryo development and endometrial receptivity must be synchronized and an adequa
Externí odkaz:
https://doaj.org/article/8fde655854e34d3da34d790977f972bf
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The uterus-lining endometrium is essential to mammalian reproduction, receiving and accommodating the embryo for proper development. Despite its key role, mechanisms underlying endometrial biology (menstrual cycling, embryo interaction) and disease a
Externí odkaz:
https://doaj.org/article/63ea14e7f59a40588b65efe393e24516
Autor:
Emma Laporte, Hugo Vankelecom
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The pituitary gland represents the hub of our endocrine system. Its cells produce specific hormones that direct multiple vital physiological processes such as body growth, fertility, and stress. The gland also contains a population of stem cells whic
Externí odkaz:
https://doaj.org/article/5b53d03f086548d6a89b2b79ccc0d44f
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Recently, we discovered that the cytokine interleukin-6 (IL-6) acts as a pituitary stem cell-activating factor, both when administered in vivo and when added to stem cell organoid cultures in vitro. Moreover, its expression, predominantly localized i
Externí odkaz:
https://doaj.org/article/91dfcc0236014472b604aa28375cfe11
Autor:
Florian Hermans, Celine Bueds, Lara Hemeryck, Ivo Lambrichts, Annelies Bronckaers, Hugo Vankelecom
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Single-cell (sc) omics has become a powerful tool to unravel a tissue’s cell landscape across health and disease. In recent years, sc transcriptomic interrogation has been applied to a variety of tooth tissues of both human and mouse, which has con
Externí odkaz:
https://doaj.org/article/4185ea58d5e54be48c159c57ec0459ae
Autor:
Andrea Romano, Sun-Wei Guo, Jan Brosens, Asgerally Fazlebas, Caroline E Gargett, Stefan Giselbrecht, Martin Gotte, Linda Griffith, Hugh S Taylor, Robert N Taylor, Hugo Vankelecom, Charles Chapron, Xiao-Hong Chang, Khaleque N Khan, Paola Vigano
Publikováno v:
Reproduction and Fertility, Vol 3, Iss 3, Pp G1-G8 (2022)
In vitro culturing of endometrial cells obtained from the uterine mucosa or ectopic sites is used to study molecular and cellular signalling relevant to physiologic and pathologic reproductive conditions. However, the lack of consensus on standard op
Externí odkaz:
https://doaj.org/article/08bdf768b4204bce9ad6f1c86dae5128
Autor:
Indra Van Zundert, Nina Maenhoudt, Silke De Vriendt, Hugo Vankelecom, Beatrice Fortuni, Susana Rocha
Publikováno v:
Bio-Protocol, Vol 12, Iss 14 (2022)
Over the past years, research has made impressive breakthroughs towards the development and implementation of 3D cell models for a wide range of applications, such as drug development and testing, organogenesis, cancer biology, and personalized medic
Externí odkaz:
https://doaj.org/article/2ec70714b51b4c3cb835573e7fa6d7c6
Autor:
Emma Laporte, Florian Hermans, Silke De Vriendt, Annelies Vennekens, Diether Lambrechts, Charlotte Nys, Benoit Cox, Hugo Vankelecom
Publikováno v:
eLife, Vol 11 (2022)
The pituitary represents the endocrine master regulator. In mouse, the gland undergoes active maturation immediately after birth. Here, we in detail portrayed the stem cell compartment of neonatal pituitary. Single-cell RNA-sequencing pictured an act
Externí odkaz:
https://doaj.org/article/0efcee480a6f48e3816e78f63c5b172b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Teeth play essential roles in life. Their development relies on reciprocal interactions between the ectoderm-derived dental epithelium and the underlying neural crest-originated mesenchyme. This odontogenic process serves as a prototype model for the
Externí odkaz:
https://doaj.org/article/0ad6103b216b41cbb6a24201aa2b7b75