Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hugo Sandman"'
Autor:
E van Duijn, Willem Seinen, T Alves, Mlh Vlaming, Manuel J.T. Carrondo, Dillingh, A Fidder, Cristina Peixoto, Raf de Ligt, Whj Vaes, Ruud Brands, Albert D. Windhorst, MC de Koning, WJ Pasman, Hugo Sandman, N. H. Hendrikse, B.O. Fabriek, J. Burggraaf, Sieto Bosgra, Pam Peeters, Jaj Mocking
Publikováno v:
Clinical Pharmacology & Therapeutics, 98(2), 196-204. Wiley-Blackwell
Clinical pharmacology and therapeutics, 2, 98, 196-204
Vlaming, M L H, van Duijn, E, Dillingh, M R, Brands, R, Windhorst, A D, Hendrikse, N H, Bosgra, S, Burggraaf, J, Koning, M C, Fidder, A, Mocking, J A J, Sandman, H, de Ligt, R A F, Fabriek, B O, Pasman, W J, Seinen, W, Alves, T, Carrondo, M, Peixoto, C, Peeters, P A M & Vaes, W H J 2015, ' Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages ', Clinical Pharmacology & Therapeutics, vol. 98, no. 2, pp. 196-204 . https://doi.org/10.1002/cpt.131
Clinical pharmacology and therapeutics, 2, 98, 196-204
Vlaming, M L H, van Duijn, E, Dillingh, M R, Brands, R, Windhorst, A D, Hendrikse, N H, Bosgra, S, Burggraaf, J, Koning, M C, Fidder, A, Mocking, J A J, Sandman, H, de Ligt, R A F, Fabriek, B O, Pasman, W J, Seinen, W, Alves, T, Carrondo, M, Peixoto, C, Peeters, P A M & Vaes, W H J 2015, ' Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages ', Clinical Pharmacology & Therapeutics, vol. 98, no. 2, pp. 196-204 . https://doi.org/10.1002/cpt.131
Preclinical development of new biological entities (NBEs), such as human protein therapeutics, requires considerable expenditure of time and costs. Poor prediction of pharmacokinetics in humans further reduces net efficiency. In this study, we show f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a65bd50d68b12c68244ff2a9754319
http://resolver.tudelft.nl/uuid:de1d0c5d-f878-4f4a-ac97-74e0d45797a9
http://resolver.tudelft.nl/uuid:de1d0c5d-f878-4f4a-ac97-74e0d45797a9
Autor:
N. Harry Hendrikse, Hugo Sandman, Birgit C. P. Koch, Catherijne A. J. Knibbe, Dick Tibboel, Albert D. Windhorst, Dimitri Grossouw, Miriam G. Mooij, Paul J. J. M. Janssen, Edwin Spaans, Wouter H. J. Vaes, Babs O. Fabriek, Esther van Duijn, Lidwien M. Hanff, Saskia N. de Wildt
Publikováno v:
Mooij, M G, van Duijn, E, Knibbe, C A J, Windhorst, A D, Hendrikse, N H, Vaes, W H J, Spaans, E, Fabriek, B O, Sandman, H, Grossouw, D, Hanff, L M, Janssen, P J J M, Koch, B C P, Tibboel, D & De Wildt, S N 2014, ' Pediatric Microdose Study of [C-14] Paracetamol to Study Drug Metabolism Using Accelerated Mass Spectrometry: Proof of Concept ', Clinical Pharmacokinetics, vol. 53, no. 11, pp. 1045-1051 . https://doi.org/10.1007/s40262-014-0176-8
Clinical Pharmacokinetics, 53(11), 1045-1051. Adis
Clinical Pharmacokinetics
Clinical Pharmacokinetics, 53(11), 1045-1051. Adis International Ltd
Clinical Pharmacokinetics, 53(11), 1045-1051. Adis
Clinical Pharmacokinetics
Clinical Pharmacokinetics, 53(11), 1045-1051. Adis International Ltd
Background Pediatric drug development is hampered by practical, ethical, and scientific challenges. Microdosing is a promising new method to obtain pharmacokinetic data in children with minimal burden and minimal risk. The use of a labeled oral micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b562019fe99031ca8777569b7598625
https://research.vumc.nl/en/publications/476c76db-1e92-4d56-ad15-256dd3ed20ee
https://research.vumc.nl/en/publications/476c76db-1e92-4d56-ad15-256dd3ed20ee
Autor:
W.E.J.M. Ghijsen, Marco van de Velde, Pieter Hengst, Fernando H. Lopes da Silva, Matthijs Verhage, Fred Mosselveld, Hugo Sandman
Publikováno v:
Journal of Neurochemistry. 58:1313-1320
To study the release of neurotransmitters, i.e., the recruitment of transmitters for release and the regulation of the release process, isolated nerve terminals (synaptosomes) of the rat forebrain were immobilized in Sephadex gel inside a perfusion c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3544055bd3a38b6dfb462ad843732be0
https://doi.org/10.1111/j.1471-4159.1992.tb11344.x
https://doi.org/10.1111/j.1471-4159.1992.tb11344.x
