Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Hugo R. Arias"'
Autor:
Hugo R. Arias, Laura Micheli, Deborah Rudin, Ophelie Bento, Saskia Borsdorf, Clara Ciampi, Philippe Marin, Evgeni Ponimaskin, Dina Manetti, Maria Novella Romanelli, Carla Ghelardini, Matthias E. Liechti, Lorenzo Di Cesare Mannelli
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116867- (2024)
The aim of this study was to determine the anti-hypersensitivity activity of novel non-hallucinogenic compounds derived from iboga alkaloids (i.e., ibogalogs), including tabernanthalog (TBG), ibogainalog (IBG), and ibogaminalog (DM506), using mouse m
Externí odkaz:
https://doaj.org/article/c642e18ca6d94d9db88979a07890f2b3
Autor:
Spencer R. Pierce, Allison L. Germann, Sophia Q. Xu, Saumith L. Menon, Marcelo O. Ortells, Hugo R. Arias, Gustav Akk
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 698 (2023)
The positive allosteric modulators (PAMs) of the α7 nicotinic receptor N-(5-Cl-2-hydroxyphenyl)-N′-[2-Cl-5-(trifluoromethyl)phenyl]-urea (NS-1738) and (E)-3-(furan-2-yl)-N-(p-tolyl)-acrylamide (PAM-2) potentiate the α1β2γ2L GABAA receptor throu
Externí odkaz:
https://doaj.org/article/7b45852e7ea54e64b1ae9c0efcc1c93d
Autor:
Dina Manetti, Silvia Dei, Hugo R. Arias, Laura Braconi, Alessio Gabellini, Elisabetta Teodori, Maria Novella Romanelli
Publikováno v:
Molecules, Vol 28, Iss 3, p 1270 (2023)
Positive allosteric modulators (PAMs), negative allosteric modulators (NAMs), silent agonists, allosteric activating PAMs and neutral or silent allosteric modulators are compounds capable of modulating the nicotinic receptor by interacting at alloste
Externí odkaz:
https://doaj.org/article/afa0960c813f46e7a046a8340201fde9
Publikováno v:
Molecules, Vol 26, Iss 8, p 2149 (2021)
It is generally assumed that selective serotonin reuptake inhibitors (SSRIs) induce antidepressant activity by inhibiting serotonin (5-HT) reuptake transporters, thus elevating synaptic 5-HT levels and, finally, ameliorates depression symptoms. New e
Externí odkaz:
https://doaj.org/article/58d44cf5ed0f46e0a76b6f38883f65cb
Autor:
Hugo R. Arias
Publikováno v:
Marine Drugs, Vol 4, Iss 3, Pp 37-69 (2006)
Abstract: This introductory minireview points out the importance of ion channels for cell communication. The basic concepts on the structure and function of ion channels triggered by membrane voltage changes, the so-called voltage-gated ion channels
Externí odkaz:
https://doaj.org/article/288406bf53f24122962a95a916dcebc4
Autor:
Hugo R. Arias, Kuo-Chen Chou, Dong-Qing Wei, Kelly MacDougall, Susan LeFrancois, Kristin Wildeboer, Ferenc Soti, William Kem
Publikováno v:
Marine Drugs, Vol 4, Iss 3, Pp 255-273 (2006)
Abstract: Nemertines are a phylum of carnivorous marine worms that possess a variety of alkaloidal, peptidic or proteinaceous toxins that serve as chemical defenses against potential predators. The hoplonemertines additionally envenomate their prey w
Externí odkaz:
https://doaj.org/article/351ffeb6adc34ab383c6ba58635f829d
Autor:
Hugo R, Arias, Allison L, Germann, Spencer R, Pierce, Seiji, Sakamoto, Marcelo O, Ortells, Itaru, Hamachi, Gustav, Akk
Publikováno v:
British Journal of Pharmacology. 179:5323-5337
Positive allosteric modulators of the α7 nicotinic acetylcholine (nACh) receptor (α7-PAMs) possess promnesic and procognitive properties and have potential in the treatment of cognitive and psychiatric disorders including Alzheimer's disease and sc
Autor:
Jacob D. Layne, Mason J. Hochstetler, Brandon M. Curry, Benjamin M. Williams, Christina A. Small, Scott C. Steffensen, Hugo R. Arias, Craig T. Werner
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.
Autor:
Eda Koseli, Belle Buzzi, Edward Choi, Torin Honaker, Javier González-Maeso, Jason Youkin, Dina Manetti, Maria Novella Romanelli, Hugo R. Arias, M. Imad Damaj
Publikováno v:
The Journal of Pain. 24:6-7
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 158:106405