Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hugo Moreiras"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cutaneous melanoma can be a most challenging neoplasm of high lethality, in part due to its extreme heterogeneity and characteristic aggressive and invasive nature. Indeed, its moniker ‘the great masquerader’ reflects that not all melanomas are c
Externí odkaz:
https://doaj.org/article/c0857677738a46c3934ddef35d783fd9
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4466 (2021)
The mechanisms by which the pigment melanin is transferred from melanocytes and processed within keratinocytes to achieve skin pigmentation remain ill-characterized. Nevertheless, several models have emerged in the past decades to explain the transfe
Externí odkaz:
https://doaj.org/article/6b32da3706b14da8a68be72449822a4e
Publikováno v:
Experimental Dermatology. 30:1324-1331
Melanin is synthesised within melanocytes and transferred to keratinocytes in human skin, thereby regulating skin colour and protecting skin cells against UVR-induced damage. We commonly divide human skin into six phototypes (SPT)-I to -VI (Fitzpatri
Publikováno v:
Traffic
Autor:
Miguel C. Seabra, Liliana Bento-Lopes, Duarte C. Barral, Matilde V. Neto, Hugo Moreiras, Tiago C. Festas, Francisco J.C. Pereira
Publikováno v:
Pigment Cell & Melanoma Research. 33:366-371
Skin pigmentation involves the production of the pigment melanin by melanocytes, in melanosomes and subsequent transfer to keratinocytes. Within keratinocytes, melanin polarizes to the apical perinuclear region to form a protective cap, shielding the
Autor:
Matilde V. Neto, Cristina Escrevente, Miguel C. Seabra, Liliana Bento-Lopes, Duarte C. Barral, José S. Ramalho, Hugo Moreiras
In the skin epidermis, melanin is produced and stored within melanosomes in melanocytes and then transferred to keratinocytes. Different models have been proposed to explain the melanin transfer mechanism, which differ essentially in how melanin is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c41b69051462afb3d31259a12ac7d032
https://doi.org/10.1101/2021.04.13.439501
https://doi.org/10.1101/2021.04.13.439501
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4466, p 4466 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 4466, p 4466 (2021)
The mechanisms by which the pigment melanin is transferred from melanocytes and processed within keratinocytes to achieve skin pigmentation remain ill-characterized. Nevertheless, several models have emerged in the past decades to explain the transfe
Publikováno v:
Traffic
The mechanisms that regulate skin pigmentation have been the subject of intense research in recent decades. In contrast with melanin biogenesis and transport within melanocytes, little is known about how melanin is transferred and processed within ke