Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Hugo Lavoie"'
Autor:
David Kachaner, Damien Garrido, Haytham Mehsen, Karine Normandin, Hugo Lavoie, Vincent Archambault
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Drosophila Polo kinase is the founding member of the Polo-Like Kinase (PLK) family and a master regulator of mitosis and cytokinesis. Here the authors uncover a molecular mechanism for the spatiotemporal regulation of Polo kinase during mitotic entry
Externí odkaz:
https://doaj.org/article/389f2a1bbd0141f2bc14a48f419d8a3f
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
RAF family kinases transmit signals from activated RAS at the plasma membrane to downstream kinases to control cell proliferation, differentiation and survival. Here the authors shed light on the molecular mechanisms whereby small molecule RAF inhibi
Externí odkaz:
https://doaj.org/article/72b7a7f1b9c84f32af4cc1decc0c0c7c
Autor:
Louis-Philippe Corbeil-Girard, Arnaud F. Klein, A. Marie-Josée Sasseville, Hugo Lavoie, Marie-Josée Dicaire, Anik Saint-Denis, Martin Pagé, André Duranceau, François Codère, Jean-Pierre Bouchard, George Karpati, Guy A. Rouleau, Bernard Massie, Yves Langelier, Bernard Brais
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 3, Pp 551-567 (2005)
Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disease caused by expanded (GCN)12–17 stretches encoding the N-terminal polyalanine domain of the poly(A) binding protein nuclear 1 (PABPN1). OPMD is characterized by intranuclear inclusio
Externí odkaz:
https://doaj.org/article/6cbdc2c5acff4c02871cd0c0aa7a1ad8
Publikováno v:
PLoS Biology, Vol 8, Iss 3, p e1000329 (2010)
Gene expression variation between species is a major contributor to phenotypic diversity, yet the underlying flexibility of transcriptional regulatory networks remains largely unexplored. Transcription of the ribosomal regulon is a critical task for
Externí odkaz:
https://doaj.org/article/f7b9521910f846f68f2c86ba02aee529
Autor:
Jean Albert, Eldon Puckrin, Jean-Marc Thériault, Hugo Lavoie, Alexandre Thibeault, Yotam Ariel, Richard L. Lachance
Publikováno v:
Portable Spectroscopy and Spectrometry
Autor:
Hugo Lavoie, Marc Therrien
Publikováno v:
Nature. 609:248-249
Publikováno v:
OSA Optical Sensors and Sensing Congress 2021 (AIS, FTS, HISE, SENSORS, ES).
First responders and military personnel are often faced with safety situations involving the task of detectiing and identifying chemical threats. These threats have become increasingly more prevalent over the last decade. The presentation will cover
Autor:
Michael Prakesch, Rima Al-awar, Ahmed Aman, Pierre Maisonneuve, Lauren Caldwell, Derek F. Ceccarelli, Ganna Posternak, Theo Goullet de Rugy, Mikko Taipale, Igor Kurinov, Julia Kitaygorodsky, Pavel Mader, Karen Colwill, Gennady Poda, Brett Larsen, Anne-Claude Gingras, Kin Chan, Jeff Wrana, Ting Jin, Salima Daou, Marc Therrien, Stephen Orlicky, Hugo Lavoie, Daniel Durocher, Xiaojing Tang, Cassandra J. Wong, Frank Sicheri, David Uehling, Robert A. Batey, Zhe Yin, Stefan Maier
Publikováno v:
Nat Chem Biol
The RAF family kinases function in the RAS-ERK pathway to transmit signals from activated RAS to the downstream kinases MEK and ERK. This pathway regulates cell proliferation, differentiation and survival, enabling mutations in RAS and RAF to act as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d3e2daaba5123ff078df9ce3f29cce
https://europepmc.org/articles/PMC7862923/
https://europepmc.org/articles/PMC7862923/
Publikováno v:
Nature reviews. Molecular cell biology. 21(10)
The proteins extracellular signal-regulated kinase 1 (ERK1) and ERK2 are the downstream components of a phosphorelay pathway that conveys growth and mitogenic signals largely channelled by the small RAS GTPases. By phosphorylating widely diverse subs