Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hugo Lana"'
Autor:
María Merino, Teresa Lozano, Noelia Casares, Hugo Lana, Iñaki F. Troconiz, Timo L. M. ten Hagen, Grazyna Kochan, Pedro Berraondo, Sara Zalba, María J. Garrido
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background The immunomodulation of the antitumor response driven by immunocheckpoint inhibitors (ICIs) such as PD-L1 (Programmed Death Ligand-1) monoclonal antibody (α-PD-L1) have shown relevant clinical outcomes in a subset of patients. Th
Externí odkaz:
https://doaj.org/article/6d5ca0ef8beb4eb08b6042e8a9bcd005
Autor:
Gema Marcelo, José M. García Fernández, Juan M. Benito, Ana I. Carbajo-Gordillo, José L. Jiménez Blanco, Francisco Mendicuti, Hugo Lana, Christophe Di Giorgio, Valentín Ceña, Cédric Przybylski, Hiroshi Hinou, Carmen Ortiz Mellet, Conchita Tros de Ilarduya
Publikováno v:
Biomacromolecules. 21:5173-5188
The architectural perfection and multivalency of dendrimers have made them useful for biodelivery via peripheral functionalization and the adjustment of dendrimer generations. Modulation of the core-forming and internal matrix-forming structures offe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d328de595d3895997245405c3695ebb2
https://doi.org/10.1021/acs.biomac.0c01283
https://doi.org/10.1021/acs.biomac.0c01283
Autor:
Adrià, Botet-Carreras, Cristina, Tamames-Tabar, Fabrice, Salles, Sara, Rojas, Edurne, Imbuluzqueta, Hugo, Lana, María José, Blanco-Prieto, Patricia, Horcajada
Publikováno v:
Journal of materials chemistry. B. 9(9)
Despite the interesting chemopreventive, antioxidant and antiangiogenic effects of the natural bioflavonoid genistein (GEN), its low aqueous solubility and bioavailability make it necessary to administer it using a suitable drug carrier system. Nanom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb3219f286339268c1c31dc1a2a974ff
https://pubmed.ncbi.nlm.nih.gov/33596280
https://pubmed.ncbi.nlm.nih.gov/33596280
Autor:
Grazyna Kochan, Iñaki F. Trocóniz, Teresa Lozano, Sara Zalba, Timo L.M. ten Hagen, María J. Garrido, Pedro Berraondo, Hugo Lana, María Merino, Noelia Casares
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Journal of Nanobiotechnology
Journal of Nanobiotechnology, 19(1):102. BioMed Central Ltd.
instname
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Journal of Nanobiotechnology
Journal of Nanobiotechnology, 19(1):102. BioMed Central Ltd.
Background The immunomodulation of the antitumor response driven by immunocheckpoint inhibitors (ICIs) such as PD-L1 (Programmed Death Ligand-1) monoclonal antibody (α-PD-L1) have shown relevant clinical outcomes in a subset of patients. This fact h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198ba28c2c66a7700e01bf20f91b05ed
https://hdl.handle.net/10171/62009
https://hdl.handle.net/10171/62009
Autor:
Patricia Horcajada, Fabrice Salles, Adrià Botet-Carreras, C. Tamames-Tabar, Sara Rojas, Hugo Lana, Edurne Imbuluzqueta, María J. Blanco-Prieto
Publikováno v:
Journal of materials chemistry B
Journal of materials chemistry B, Royal Society of Chemistry, 2021, 9 (9), pp.2233-2239. ⟨10.1039/D0TB02804E⟩
Journal of materials chemistry B, Royal Society of Chemistry, 2021, 9 (9), pp.2233-2239. ⟨10.1039/D0TB02804E⟩
International audience; Despite the interesting chemopreventive, antioxidant and antiangiogenic effects of the natural bioflavonoid genistein (GEN), its low aqueous solubility and bioavailability make it necessary to administer it using a suitable dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8ab2dbcfb2fc12873fe5bbedc39f7e
https://hal.archives-ouvertes.fr/hal-03168325
https://hal.archives-ouvertes.fr/hal-03168325
Publikováno v:
Proceedings of The 1st International Electronic Conference on Pharmaceutics.
Introduction: Neuroblastoma is the most frequent pediatric extracranial solid tumor being responsible for 8-10% of all childhood malignancies. Patient outcome is still a major issue due to neuroblastoma’s heterogeneity and complex tumor biology.1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909ec260bb83923ab68d6426e1785926
https://doi.org/10.3390/iecp2020-08800
https://doi.org/10.3390/iecp2020-08800
Autor:
Francisco Mendicuti, José M. García Fernández, Hugo Lana, Gema Marcelo, Ana I. Carbajo-Gordillo, Tania Neva, Juan M. Benito, Conchita Tros de Ilarduya, Carmen Ortiz Mellet
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 26(66)
Original molecular vectors that ensure broad flexibility to tune the shape and surface properties of plasmid DNA (pDNA) condensates are reported herein. The prototypic design involves a cyclodextrin (CD) platform bearing a polycationic cluster at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c2b61fc16be7ff104707fba2b1d077
https://pubmed.ncbi.nlm.nih.gov/32710799
https://pubmed.ncbi.nlm.nih.gov/32710799
Autor:
María J. Blanco-Prieto, Melissa Guada, Maria del Carmen Dios-Viéitez, Ana Gloria Gil, Hugo Lana
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 101:112-118
The pharmacodynamic effect and the safety of cyclosporine A lipid nanoparticles (CsA LN) for oral administration were investigated using Sandimmune Neoral® as reference. First, the biocompatibility of the unloaded LN on Caco-2 cells was demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cde4e8ce1208ca33bd95786d92bf549
https://doi.org/10.1016/j.ejpb.2016.01.011
https://doi.org/10.1016/j.ejpb.2016.01.011
Autor:
María J. Blanco-Prieto, Ismael Aizpún, Beatriz Lasa-Saracíbar, Ana Gloria Gil, Hugo Lana, Maria Angela Aznar
Publikováno v:
International Journal of Pharmaceutics. 474:1-5
Edelfosine, an alkyl-lysophospholipid antitumor drug with severe side-effects, has previously been encapsulated into lipid nanoparticles (LN) with the purpose of improving their toxicity profile. LN are made of lipids recognized as safe by the Food a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a9b2cdf193a4ecdaf89e6a6db03400
https://doi.org/10.1016/j.ijpharm.2014.07.053
https://doi.org/10.1016/j.ijpharm.2014.07.053
Functional benefits of PLGA particulates carrying VEGF and CoQ10 in an animal of myocardial ischemia
Autor:
Hugo Lana, Charitra N. Grama, Esther Tamayo, Carolina Benavides, M. N. V. Ravi Kumar, Teresa Simón-Yarza, Felipe Prosper, María J. Blanco-Prieto, Carlos Ortiz-de-Solorzano, Fabio Rocha Formiga
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
Myocardial ischemia (MI) remains one of the leading causes of death worldwide. Angiogenic therapy with the vascular endothelial growth factor (VEGF) is a promising strategy to overcome hypoxia and its consequences. However, from the clinical data it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca253ccac0fe310e477354590cf0169
https://doi.org/10.1016/j.ijpharm.2013.04.015
https://doi.org/10.1016/j.ijpharm.2013.04.015