Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hugo Lago-Santomé"'
Publikováno v:
The Journal of Organic Chemistry. 79:4300-4305
A fully stereocontrolled 1,3-diol orthoesterification and a water-promoted intramolecular Henry addition, combined with the previously reported formal (3 + 3) annulation of α-nitro-α,β-enals and 2,2-dimethyl-1,3-dioxan-5-one, provided for a short
Autor:
Hugo Lago-Santomé, Patricia Martínez-Bescos, Ricardo Alonso, Fernando Cagide-Fagín, Lidia Ozores-Viturro, Marta Fernández-González
Publikováno v:
The Journal of organic chemistry. 79(18)
As demonstrated with the β-(2-furyl)-substituted analogue 1b, β-aryl-α-nitro-α,β-enals (1) behave as heterodienes against enamines and enol ethers using their enal unit (e.g., 1b → 12). α-Nitro-α,β-enals can act as well as highly reactive d
Publikováno v:
The Journal of organic chemistry. 77(24)
2-Methoxymethylpyrrolidine best performed, among several other proline derivatives, to control the enantioselective [3+3] annulation of β-(hetero)aryl-α-nitro-α,β-enals with commercial 2,2-dimethyl-1,3-dioxan-5-one, a procedure that renders highl
Autor:
Fernando Cagide-Fagín, Juan Carlos Ortiz-Lara, Olaia Nieto-García, Ricardo Alonso, Hugo Lago-Santomé
Publikováno v:
Organicbiomolecular chemistry. 10(4)
A full account is given for the total synthesis and the cytotoxic activity against the human lung tumoral cell line NCI-H460 of (±)-7-deoxy-pancratistatin and its 2-epi- and 2,4-diepi- unnatural analogues.