Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Hugo López Fernández"'
Autor:
Miguel Reboiro-Jato, Daniel Pérez-Rodríguez, Miguel José Da Silva, David Vila-Fernández, Cristina P. Vieira, Jorge Vieira, Hugo López-Fernández
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background The initial version of SEDA assists life science researchers without programming skills with the preparation of DNA and protein sequence FASTA files for multiple bioinformatics applications. However, the initial version of SEDA la
Externí odkaz:
https://doaj.org/article/ba9b47851a8b41a6b6c4b4f4579d89a0
Autor:
Pedro Davila-Piñón, Alba Nogueira-Rodríguez, Astrid Irene Díez-Martín, Laura Codesido, Jesús Herrero, Manuel Puga, Laura Rivas, Eloy Sánchez, Florentino Fdez-Riverola, Daniel Glez-Peña, Miguel Reboiro-Jato, Hugo López-Fernández, Joaquín Cubiella
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundPolyDeep is a computer-aided detection and classification (CADe/x) system trained to detect and classify polyps. During colonoscopy, CADe/x systems help endoscopists to predict the histology of colonic lesions.ObjectiveTo compare the diagno
Externí odkaz:
https://doaj.org/article/01de0aa34aa74df4971e7b303a0dabed
Pathway-guided monitoring of the disease course in bladder cancer with longitudinal urine proteomics
Autor:
Luís Botelho Carvalho, José Luis Capelo, Carlos Lodeiro, Rajiv Dhir, Luis Campos Pinheiro, Hugo López-Fernández, Gonçalo Martins, Mariana Medeiros, Fernando Díaz, Hugo Miguel Santos
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Carvalho et al. develop an analysis pipeline for label-free urine proteomics data. Their approach allows monitoring of the disease course in patients with bladder cancer and flags the need for medical intervention.
Externí odkaz:
https://doaj.org/article/085877129f5a4c0aac521dc42edb3860
Autor:
Pedro Ferreira, Ricardo Soares, Hugo López-Fernández, Noé Vazquez, Miguel Reboiro-Jato, Cristina P. Vieira, Jorge Vieira
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2428 (2024)
SARS-CoV-2 amino acid variants that contribute to an increased transmissibility or to host immune system escape are likely to increase in frequency due to positive selection and may be identified using different methods, such as codeML, FEL, FUBAR, a
Externí odkaz:
https://doaj.org/article/b4d53820c778453a993859704bf5b974
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1230 (2023)
High-throughput sequencing of small RNA molecules such as microRNAs (miRNAs) has become a widely used approach for studying gene expression and regulation. However, analyzing miRNA-Seq data can be challenging because it requires multiple steps, from
Externí odkaz:
https://doaj.org/article/c2804862a0e74bab9975f1d0884a7ec5
Publikováno v:
Diagnostics, Vol 13, Iss 5, p 966 (2023)
Deep learning object-detection models are being successfully applied to develop computer-aided diagnosis systems for aiding polyp detection during colonoscopies. Here, we evidence the need to include negative samples for both (i) reducing false posit
Externí odkaz:
https://doaj.org/article/cd0137fb912d408095245d90b5ee09c0
Autor:
Daniel Pérez-Rodríguez, Maria Aránzazu Penedo, Tania Rivera-Baltanás, Tonatiuh Peña-Centeno, Susanne Burkhardt, Andre Fischer, José M. Prieto-González, José Manuel Olivares, Hugo López-Fernández, Roberto Carlos Agís-Balboa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 1891 (2023)
Schizophrenia (SZ) is a serious mental disorder that is typically treated with antipsychotic medication. Treatment-resistant schizophrenia (TRS) is the condition where symptoms remain after pharmacological intervention, resulting in long-lasting func
Externí odkaz:
https://doaj.org/article/7780cbc3f36345db98386e7045e520f0
Autor:
Hugo López-Fernández, Osvaldo Graña-Castro, Alba Nogueira-Rodríguez, Miguel Reboiro-Jato, Daniel Glez-Peña
Publikováno v:
PeerJ Computer Science, Vol 7, p e593 (2021)
Compi is an application framework to develop end-user, pipeline-based applications with a primary emphasis on: (i) user interface generation, by automatically generating a command-line interface based on the pipeline specific parameter definitions; (
Externí odkaz:
https://doaj.org/article/faeccdfd60c9443e876aa18359bdc2ea
Autor:
Sara Rocha, Jorge Vieira, Noé Vázquez, Hugo López-Fernández, Florentino Fdez-Riverola, Miguel Reboiro-Jato, André D. Sousa, Cristina P. Vieira
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Background Wild-type (wt) polyglutamine (polyQ) regions are implicated in stabilization of protein-protein interactions (PPI). Pathological polyQ expansion, such as that in human Ataxin-1 (ATXN1), that causes spinocerebellar ataxia type 1 (S
Externí odkaz:
https://doaj.org/article/58539774873847b3b9304bef0d7ca09d
Autor:
Sílvia F. Henriques, Pedro Duque, Hugo López-Fernández, Noé Vázquez, Florentino Fdez-Riverola, Miguel Reboiro-Jato, Cristina P. Vieira, Jorge Vieira
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background L-ascorbate (Vitamin C) is an important antioxidant and co-factor in eukaryotic cells, and in mammals it is indispensable for brain development and cognitive function. Vertebrates usually become L-ascorbate auxothrophs when the la
Externí odkaz:
https://doaj.org/article/ff34edc980c146b3b5f3bccea5869115