Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hugo H. ORTEGA"'
Autor:
Sabrina E. Vinzón, María V. Lopez, Eduardo G. A. Cafferata, Ariadna S. Soto, Paula M. Berguer, Luciana Vazquez, Leonora Nusblat, Andrea V. Pontoriero, Eduardo M. Belotti, Natalia R. Salvetti, Diego L. Viale, Ariel E. Vilardo, Martin M. Avaro, Estefanía Benedetti, Mara L. Russo, María E. Dattero, Mauricio Carobene, Maximiliano Sánchez-Lamas, Jimena Afonso, Mauro Heitrich, Alejandro E. Cristófalo, Lisandro H. Otero, Elsa G. Baumeister, Hugo H. Ortega, Alexis Edelstein, Osvaldo L. Podhajcer
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract COVID-19 vaccines were originally designed based on the ancestral Spike protein, but immune escape of emergent Variants of Concern (VOC) jeopardized their efficacy, warranting variant-proof vaccines. Here, we used preclinical rodent models t
Externí odkaz:
https://doaj.org/article/ba99e3be03244ebfae597386425015da
Autor:
LUCIANA A. CHOLICH, AGUSTÍN MARTINEZ, JUAN F. MICHELOUD, MARÍA E. PISTÁN, ENRIQUE N. GARCÍA, CARLOS A. ROBLES, HUGO H. ORTEGA, EDUARDO J. GIMENO
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 93, Iss suppl 3 (2021)
Abstract It is well known that several of the swainsonine-containing plant species found widespread around the world have a negative economic impact in each country. In Argentina, most of the information on the poisonous plant species that produce α
Externí odkaz:
https://doaj.org/article/acb5d4cefe334448a15dab7bdd782032
Preclinical Efficacy and Toxicology Evaluation of RAC1 Inhibitor 1A-116 in Human Glioblastoma Models
Autor:
Georgina A. Cardama, Julian Maggio, Lucas Valdez Capuccino, Nazareno Gonzalez, Valentina Matiller, Hugo H. Ortega, German R. Perez, Ignacio A. Demarco, Eduardo Spitzer, Daniel E. Gomez, Pablo Lorenzano Menna, Daniel F. Alonso
Publikováno v:
Cancers, Vol 14, Iss 19, p 4810 (2022)
Malignant gliomas are the most common primary central nervous system tumor in adults. Despite current therapeutics, these tumors are associated with poor prognosis and a median survival of 16 to 19 months. This highlights the need for innovative trea
Externí odkaz:
https://doaj.org/article/7dd353e1f55b48e59a63af8bb499eeb8
Publikováno v:
Acta Herpetologica, Vol 15, Iss 1 (2020)
Multiple mechanisms have evolved for the defensive recognition of foreign components, such as microorganisms. The majority of immunological studies with vertebrates have been focused on endothermic species, and relatively little attention has been di
Externí odkaz:
https://doaj.org/article/86482cecb05341bbadcf6891d8c3ee55
Autor:
Karina L. Bierbrauer, Roxana V. Alasino, Fernando E. Barclay, Eduardo M. Belotti, Hugo H. Ortega, Dante M. Beltramo
Publikováno v:
Polymers, Vol 13, Iss 24, p 4426 (2021)
We describe the functional capability of a cross-linked hydrogel composed of sulfated glycosaminoglycans and a cationic cellulose by conducting trials on experimental animal models using intra-articular implants to treat an articular disease called o
Externí odkaz:
https://doaj.org/article/e4cf1eac12b64e2f9ee4b2c83de3ea84
Autor:
M. Verónica López, Sabrina E. Vinzón, Eduardo G. A. Cafferata, Felipe J. Núñez, Ariadna Soto, Maximiliano Sanchez-Lamas, M. Jimena Afonso, Diana Aguilar-Cortes, Gregorio D. Ríos, Juliana T. Maricato, Carla T. Braconi, Vanessa B. Silveira, Tatiane M. Andrad, Tatiana C. S. Bonetti, Luiz M. Ramos Janini, Manoel J. B. C. Girão, Andrea S. Llera, Karina A. Gomez, Hugo H. Ortega, Paula M. Berguer, Osvaldo L. Podhajcer
Publikováno v:
Vaccines, Vol 9, Iss 10, p 1106 (2021)
Most approved vaccines against COVID-19 have to be administered in a prime/boost regimen. We engineered a novel vaccine based on a chimeric human adenovirus 5 (hAdV5) vector. The vaccine (named CoroVaxG.3) is based on three pillars: (i) high expressi
Externí odkaz:
https://doaj.org/article/b0086f266e2e4a949a588004e905c559
Autor:
Fabiano J.F. de Sant'Ana, Janildo L. Reis Junior, Rosélia L.S. Araújo, Eduardo J.Gimeno, Hugo H. Ortega
Publikováno v:
Pesquisa Veterinária Brasileira, Vol 35, Iss 2, Pp 119-124 (2015)
The expression of cytoskeletal proteins was evaluated immunohistochemically in 36 normal ovaries sampled from 18 sows and 44 cystic ovaries sampled from of 22 sows, was evaluated. All sows had history of reproductive problems, such as infertility or
Externí odkaz:
https://doaj.org/article/b97ccd4a78b94b2ea3ee70978c1b2160
Publikováno v:
Brazilian Journal of Veterinary Research and Animal Science, Vol 41, Iss 6 (2004)
Numerosos modelos experimentais têm sido desenvolvimos para o estudo da síndrome do ovário policístico em ratos. No presente estudo, a síndrome foi inducida por exposição à luz constante. O processo foi avaliado durante sua indução e inclus
Externí odkaz:
https://doaj.org/article/bc1b4180ac43428088d9aa1bff14d4a5
Autor:
Emmanuel Angeli, Daiana Barcarolo, Lucas E. Ribas, Valentina Matiller, Silvina M. Addona, Florencia Rey, Hugo H. Ortega, Gustavo J. Hein
Publikováno v:
Veterinary Research Communications.
Autor:
Belkis MARELLI, Hugo H. ORTEGA, Florencia Martín OLMOS, María Sol RENNA, María Eugenia BARAVALLE, Natalia VELAZQUEZ, Paula SILVESTRINI, Lucas ETCHEVERS
Publikováno v:
FAVE Sección Ciencias Veterinarias. 20:44-50
La inmunoterapia pasiva como tratamiento contra el virus SARS-CoV-2 (del inglés, severe acute respiratory syndrome coronavirus-2) requiere de la cuantificación de la capacidad neutralizante de los anticuerpos para el desarrollo de terapias efectiva