Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Hugo Arias-Pulido"'
Autor:
Guillermo Valdivia, Daniel Alonso-Miguel, Maria Dolores Perez-Alenza, Anna Barbara Emilia Zimmermann, Evelien Schaafsma, Fred W. Kolling, Lucia Barreno, Angela Alonso-Diez, Veronique Beiss, Jessica Fernanda Affonso de Oliveira, María Suárez-Redondo, Steven Fiering, Nicole F. Steinmetz, Johannes vom Berg, Laura Peña, Hugo Arias-Pulido
Publikováno v:
Cells, Vol 12, Iss 18, p 2241 (2023)
The lack of optimal models to evaluate novel agents is delaying the development of effective immunotherapies against human breast cancer (BC). In this prospective open label study, we applied neoadjuvant intratumoral immunotherapy with empty cowpea m
Externí odkaz:
https://doaj.org/article/0668121ab3dc495694ac8429e8537724
Autor:
Emily L. Giddings, Devin P. Champagne, Meng-Han Wu, Joshua M. Laffin, Tina M. Thornton, Felipe Valenca-Pereira, Rachel Culp-Hill, Karen A. Fortner, Natalia Romero, James East, Phoebe Cao, Hugo Arias-Pulido, Karatatiwant S. Sidhu, Brian Silverstrim, Yoonseok Kam, Shana Kelley, Mark Pereira, Susan E. Bates, Janice Y. Bunn, Steven N. Fiering, Dwight E. Matthews, Robert W. Robey, Domink Stich, Angelo D’Alessandro, Mercedes Rincon
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Drug efflux through ABC transporters is a common mechanism leading to chemoresistance in cancer. Here, the authors show that mitochondrial respiration provides ATP to allow ABC transporters activity so mitochondrial respiration inhibition overcomes c
Externí odkaz:
https://doaj.org/article/96cc5e262fc1481b86eceff834f1a9ce
Autor:
Daniel Alonso-Miguel, Guillermo Valdivia, Diego Guerrera, Maria Dolores Perez-Alenza, Stanislav Pantelyushin, Angela Alonso-Diez, Veronique Beiss, Steven Fiering, Nicole F Steinmetz, Maria Suarez-Redondo, Johannes vom Berg, Laura Peña, Hugo Arias-Pulido
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Inflammatory mammary cancer (IMC), the counterpart of human inflammatory breast cancer (IBC), is the deadliest form of canine mammary tumors. IMC patients lack specific therapy and have poor outcomes. This proof-of-principle preclinical st
Externí odkaz:
https://doaj.org/article/c925ae8c4b2e44539ed0f0f302b29ca8
Publikováno v:
Cells, Vol 11, Iss 18, p 2850 (2022)
Inflammatory breast cancer (IBC) is highly metastatic at the onset of the disease with no IBC-specific treatments, resulting in dismal patient survival. IBC treatment is a clear unmet clinical need. This commentary highlights findings from a recent s
Externí odkaz:
https://doaj.org/article/5e11a24d3e2949a688225c56a4181d89
Autor:
Kun Yang, Colin Mooney, Greg Spahlinger, Scott Schuetze, Hugo Arias-Pulido, Claire Verschraegen, Phyllis Gimotty, Ronald J Buckanovich
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36525 (2012)
The Death Receptor 6 (DR6) protein is elevated in the serum of ovarian cancer patients. We tested DR6 serum protein levels as a diagnostic/predictive biomarker in several epithelial tumors and sarcomas.DR6 gene expression profiles were screened in pu
Externí odkaz:
https://doaj.org/article/57cde1f854d04b13997c87144ef8d42a
Autor:
Susan Band Horwitz, Harriet O. Smith, Gary L. Goldberg, Eric R. Prossnitz, Clifford R. Qualls, Hugo Arias-Pulido, Juan Lin, Tiffany M. Hebert, Christine H. Kim, Marissa J. Ramirez, Jurriaan Brouwer-Visser, Gloria S. Huang
Supplementary Data from Insulin-like Growth Factor 2 Expression Modulates Taxol Resistance and Is a Candidate Biomarker for Reduced Disease-Free Survival in Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af34962147213cdc6c0757ea3de5344
https://doi.org/10.1158/1078-0432.22442106
https://doi.org/10.1158/1078-0432.22442106
Autor:
Susan Band Horwitz, Harriet O. Smith, Gary L. Goldberg, Eric R. Prossnitz, Clifford R. Qualls, Hugo Arias-Pulido, Juan Lin, Tiffany M. Hebert, Christine H. Kim, Marissa J. Ramirez, Jurriaan Brouwer-Visser, Gloria S. Huang
Purpose: This study was undertaken to examine the role of the insulin-like growth factor (IGF) signaling pathway in the response of ovarian cancer cells to Taxol and to evaluate the significance of this pathway in human epithelial ovarian tumors.Expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed4976505daec1f5287aa55d839e8ce
https://doi.org/10.1158/1078-0432.c.6518928.v1
https://doi.org/10.1158/1078-0432.c.6518928.v1
Autor:
Daniel Alonso-Miguel, Guillermo Valdivia, Barbara Zimmermann, Lucia Lucia Barreno, Angela Alonso-Diez, Maria Dolores Perez-Alenza, Veronique Beiss, María Suárez-Redondo, Nicole Steinmetz, Steven Fiering, Johannes Vom Berg, Laura Laura Peña, Hugo Arias-Pulido
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Nancy E. Joste, Hugo Arias-Pulido, Mary D. Chamberlin, Ashley Cimino-Mathews, Leisha A. Emens, Eric R. Prossnitz, Clifford Qualls, Nabila Chaher, Steven Fiering, Jonathan D. Marotti, Maxwell Gabriel Foisey, Cecile Colpaert
Publikováno v:
Breast Cancer Res Treat
PURPOSE: This study evaluated epidemiologic and immune factors associated with pathologic complete response (pCR), breast cancer-specific survival (BCSS) and disease-free survival (DFS) outcomes in inflammatory (IBC) and locally advanced breast cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e729e1e29577c27c78b6f30a1e0c6c
https://europepmc.org/articles/PMC8603784/
https://europepmc.org/articles/PMC8603784/
Autor:
Devin P. Champagne, Karatatiwant Singh Sidhu, Robert W. Robey, Angelo D'Alessandro, Janice Y. Bunn, Susan E. Bates, Brian Silverstrim, Tina M. Thornton, Steven Fiering, Joshua M. Laffin, Karen A. Fortner, Dwight E. Matthews, Hugo Arias-Pulido, Felipe Valença-Pereira, Natalia Romero, Mercedes Rincon, Shana O. Kelley, Mark P. Pereira, Phoebe Cao, Domink Stich, Emily Giddings, Meng Han Wu, Yoonseok Kam, James East, Rachel Culp-Hill
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Chemotherapy remains the standard of care for most cancers worldwide, however development of chemoresistance due to the presence of the drug-effluxing ATP binding cassette (ABC) transporters remains a significant problem. The development of safe and