Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hugo Arellano-Santoyo"'
Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization
Autor:
Ray Yu-Ruei Wang, Hugo Arellano-Santoyo, Emma Stokasimov, Andres E. Leschziner, Rogelio A. Hernandez-Lopez, David Pellman
The microtubule (MT) cytoskeleton is central to cellular processes including axonal growth, intracellular transport, and cell division, all of which rely on precise spatiotemporal control of MT organization. Kinesin-8s play a key role in regulating M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c769dffcffe177f9f865e1ee3b595d18
https://doi.org/10.1101/2021.10.12.464151
https://doi.org/10.1101/2021.10.12.464151
Autor:
Jeffrey A. Porter, Hera Vlamakis, A. Brantley Hall, Zachary A. Costliow, Michael A. Durney, Emily R. Temple, Damian R. Plichta, Hugo Arellano-Santoyo, Xiebin Gu, Eric M. Brown, Matthieu Pichaud, Kai Liu, Clary A. Clish, Ramnik J. Xavier
Publikováno v:
Cell Host & Microbe. 29:1351-1365.e11
Summary Bacterial ADP-ribosyltransferases (ADPRTs) have been described as toxins involved in pathogenesis through the modification of host proteins. Here, we report that ADPRTs are not pathogen restricted but widely prevalent in the human gut microbi
Autor:
Luke M. Rice, Elisabeth A. Geyer, William O. Hancock, Hugo Arellano-Santoyo, Xiaolei Su, Ema Stokasimov, Geng-Yuan Chen, David Pellman
Summary Kinesin-8 motors regulate the size of microtubule structures, using length-dependent accumulation at the plus end to preferentially disassemble long microtubules. Despite extensive study, the kinesin-8 depolymerase mechanism remains under deb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe23c6b76ace609ae173cab5f04f57c
https://europepmc.org/articles/PMC5573156/
https://europepmc.org/articles/PMC5573156/
Publikováno v:
Proceedings of the National Academy of Sciences. 107:9182-9185
A filamentous cytoskeleton largely governs the physical shape and mechanical properties of eukaryotic cells. In bacteria, proteins homologous to all three classes of eukaryotic cytoskeletal filaments have recently been discovered. These proteins are
Autor:
David Pellman, Hugo Arellano-Santoyo, Marylin Vantard, Xiaolei Su, Jérémie Gaillard, Manuel Thery, Didier Portran
Publikováno v:
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2013, 15 (8), pp.948-57. ⟨10.1038/ncb2801⟩
Nature Cell Biology, 2013, 15 (8), pp.948-57. ⟨10.1038/ncb2801⟩
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2013, 15 (8), pp.948-57. ⟨10.1038/ncb2801⟩
Nature Cell Biology, 2013, 15 (8), pp.948-57. ⟨10.1038/ncb2801⟩
Nature cell biology
International audience; Molecular motors play critical roles in the formation of mitotic spindles, either through controlling the stability of individual microtubules, or by crosslinking and sliding microtubule arrays. Kinesin-8 motors are best known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5831051220cc54b41953fbd1daff77
https://hal.archives-ouvertes.fr/hal-00873347
https://hal.archives-ouvertes.fr/hal-00873347
Publikováno v:
Journal of Visualized Experiments.
We developed a protocol to measure the bending rigidity of filamentous rod-shaped bacteria. Forces are applied with an optical trap, a microscopic three-dimensional spring made of light that is formed when a high-intensity laser beam is focused to a
Autor:
Hugo Arellano-Santoyo, Tamir Gonen, Charles L. Asbury, Bungo Akiyoshi, Sue Biggins, Jeffrey A. Ranish, Andrew F. Powers, Christian R. Nelson, Krishna K. Sarangapani, Steve L. Reichow
Publikováno v:
Nature. 468(7323)
The kinetochore is the large protein complex that assembles on centromeric DNA to mediate chromosome separation. For decades, researchers have tried to isolate whole functional kinetochores without success. Sue Biggins and colleagues now report the f
Publikováno v:
Biophysical Journal. 96(3)
The envelope of a gram-negative bacterium is composed of three layers: the inner and outer membranes and the periplasmic peptidoglycan (PG) cell wall. The PG layer is thought to be the stress bearing structure that determines and maintains cell shape
Autor:
Charles L. Asbury, Nicole Duggan, Sue Biggins, Jonathan W. Driver, Andrew F. Powers, Krishna K. Sarangapani, Hugo Arellano-Santoyo, Bungo Akiyoshi
Publikováno v:
Biophysical Journal. 102:222a
An exquisite molecular machine, the mitotic spindle, organizes and separates chromosomes during cell division. To uncover how this machine operates we are reconstituting spindle functions and applying advanced biophysical tools for manipulating and t
Autor:
Krishna K. Sarangapani, Hugo Arellano-Santoyo, Bungo Akiyoshi, Jonathan W. Driver, Nicole Duggan, Sue Biggins, Andrew F. Powers, Charles L. Asbury
Publikováno v:
Biophysical Journal. (3):700a-701a
Chromosome segregation is orchestrated by multi-protein complexes called kinetochores, which initially bind microtubules and later form persistent load-bearing tip attachments. Accurate segregation requires regulation of kinetochores by Aurora B kina