Zobrazeno 1 - 10
of 2 085
pro vyhledávání: '"Hugo A. Katus"'
Autor:
Bastian Bruns, Maximilian Joos, Nesrin Elsous, Hugo A. Katus, Jobst‐Hendrik Schultz, Norbert Frey, Johannes Backs, Benjamin Meder
Publikováno v:
ESC Heart Failure, Vol 11, Iss 3, Pp 1515-1524 (2024)
Abstract Aims Takotsubo syndrome (TTS) is an acute heart failure (AHF) syndrome mimicking the symptoms of acute myocardial infarction. Impaired outcome has been shown, making risk stratification and novel therapeutic concepts a necessity. We hypothes
Externí odkaz:
https://doaj.org/article/ba60e5a28f0544af8dbb208d6c71e0cb
Autor:
Sebastian W. Romann, Daniel Finke, Markus B. Heckmann, Hauke Hund, Evangelos Giannitsis, Hugo A. Katus, Norbert Frey, Lorenz H. Lehmann
Publikováno v:
ESC Heart Failure, Vol 11, Iss 1, Pp 366-377 (2024)
Abstract Aims Oncological patients suspected at risk for cardiotoxicity are recommended to undergo intensified cardiological surveillance. We investigated the value of cardiac biomarkers and patient‐related risk factors [age, cardiovascular risk fa
Externí odkaz:
https://doaj.org/article/3c19aca609eb40cbba1ea8736f76682f
Autor:
Christian Salbach, Mustafa Yildirim, Hauke Hund, Moritz Biener, Matthias Müller‐Hennessen, Norbert Frey, Hugo A. Katus, Evangelos Giannitsis, Barbara Ruth Milles
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background For the majority of patients with atrial fibrillation (AF), disease management has improved in recent years. However, there are still populations underrepresented or excluded in current registries and randomized controlled trials. HERA‐F
Externí odkaz:
https://doaj.org/article/14b8d1d4d4d8403b9f1a7f9714ac03da
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart
Autor:
Marion Müller, Rose Eghbalian, Jes-Niels Boeckel, Karen S. Frese, Jan Haas, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Maximilian K. Lackner, Oguz F. Tugrul, Thomas Ruppert, Rewati Tappu, Diana Martins Bordalo, Jasmin M. Kneuer, Annika Piekarek, Sabine Herch, Sarah Schudy, Andreas Keller, Nadja Grammes, Cornelius Bischof, Anna Klinke, Margarida Cardoso-Moreira, Henrik Kaessmann, Hugo A. Katus, Norbert Frey, Lars M. Steinmetz, Benjamin Meder
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Phosphorylation of the essential myosin light chain (ELC) influence actin-myosin crossbridge cycling in the heart. Here, the authors show upregulated ELC-phosphorylation in systolic heart failure and identify NIMArelated kinase 9 to bind to ELC media
Externí odkaz:
https://doaj.org/article/bdd3c98ae2ae446c8307d5af259ac8e7
Autor:
Deborah Siry, Johannes Riffel, Janek Salatzki, Florian André, Lukas Damian Weberling, Marco Ochs, Noura A. Atia, Elizabeth Hillier, David Albert, Hugo A. Katus, Evangelos Giannitsis, Norbert Frey, Matthias G. Friedrich
Publikováno v:
BMC Medical Imaging, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Myocardial strain imaging has gained importance in cardiac magnetic resonance (CMR) imaging in recent years as an even more sensitive marker of early left ventricular dysfunction than left-ventricular ejection fraction (LVEF). fSE
Externí odkaz:
https://doaj.org/article/59ec925764c640ed83d8c108e4fba9c3
Autor:
Deborah Siry, Johannes H. Riffel, Janek Salatzki, Florian Andre, Marco Ochs, Lukas D. Weberling, Evangelos Giannitsis, Hugo A. Katus, Matthias G. Friedrich
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract In patients with suspected acute coronary syndrome high-sensitivity cardiac tropnonin T is used for rapid patient triage. Some acute coronary syndrome patients assigned to the observe zone based on high-sensitivity cardiac troponin T after 1
Externí odkaz:
https://doaj.org/article/b7c72c462bb842babf0b55cf7b5c2a35
Autor:
Nicolas A. Geis, Philipp Schlegel, Markus B. Heckmann, Hugo A. Katus, Norbert Frey, Patricia Crespo López, Philip W.J. Raake
Publikováno v:
ESC Heart Failure, Vol 9, Iss 2, Pp 853-865 (2022)
Abstract Aims Mitral valve transcatheter edge‐to‐edge repair (TEER) has been established as a suitable alternative to mitral valve surgery in patients with severe mitral regurgitation (MR) and high surgical risk. The PASCAL system represents a no
Externí odkaz:
https://doaj.org/article/10cc5b3d7a63488498c12301140acbcd
Autor:
Jes-Niels Boeckel, Maximilian Möbius-Winkler, Marion Müller, Sabine Rebs, Nicole Eger, Laura Schoppe, Rewati Tappu, Karoline E. Kokot, Jasmin M. Kneuer, Susanne Gaul, Diana M. Bordalo, Alan Lai, Jan Haas, Mahsa Ghanbari, Philipp Drewe-Boss, Martin Liss, Hugo A. Katus, Uwe Ohler, Michael Gotthardt, Ulrich Laufs, Katrin Streckfuss-Bömeke, Benjamin Meder
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 1, Pp 129-146 (2022)
Alternative mRNA splicing is a fundamental process to increase the versatility of the genome. In humans, cardiac mRNA splicing is involved in the pathophysiology of heart failure. Mutations in the splicing factor RNA binding motif protein 20 (RBM20)
Externí odkaz:
https://doaj.org/article/1a62d499b1c84c03a1e970a9381d3d3a
Autor:
Malgorzata Szaroszyk, Badder Kattih, Abel Martin-Garrido, Felix A. Trogisch, Gesine M. Dittrich, Andrea Grund, Aya Abouissa, Katja Derlin, Martin Meier, Tim Holler, Mortimer Korf-Klingebiel, Katharina Völker, Tania Garfias Macedo, Cristina Pablo Tortola, Michael Boschmann, Nora Huang, Natali Froese, Carolin Zwadlo, Mona Malek Mohammadi, Xiaojing Luo, Michael Wagner, Julio Cordero, Robert Geffers, Sandor Batkai, Thomas Thum, Nadja Bork, Viacheslav O. Nikolaev, Oliver J. Müller, Hugo A. Katus, Ali El-Armouche, Theresia Kraft, Jochen Springer, Gergana Dobreva, Kai C. Wollert, Jens Fielitz, Stephan von Haehling, Michaela Kuhn, Johann Bauersachs, Joerg Heineke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Cachexia is associated with poor prognosis in heart failure. Here the authors show that mice and patients with cardiac cachexia display reduced skeletal muscle expression and circulating levels of Musclin. Musclin ablation in skeletal muscle worsens,
Externí odkaz:
https://doaj.org/article/95984c1d58cc4de49ae09f7ddb642716
Autor:
Marcus Hjort, Kai M. Eggers, Tatevik Ghukasyan Lakic, Johan Lindbäck, Andrzej Budaj, Jan H. Cornel, Evangelos Giannitsis, Hugo A. Katus, Agneta Siegbahn, Robert F. Storey, Richard C. Becker, Lars Wallentin, Bertil Lindahl
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 1 (2023)
Background The pathobiology of myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) is often uncertain. Investigating biomarker concentrations and their changes may offer novel pathophysiological insights. Methods and Results In
Externí odkaz:
https://doaj.org/article/b7e7d209ff5640c88a4a2a76d5d286bb