Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Hugo A. Armelin"'
Autor:
Eduardo Cararo-Lopes, Matheus H. Dias, Marcelo S. da Silva, Julianna D. Zeidler, Alexandre T. Vessoni, Marcelo S. Reis, Enrique Boccardo, Hugo A. Armelin
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-16 (2021)
Abstract Malignant transformation involves an orchestrated rearrangement of cell cycle regulation mechanisms that must balance autonomic mitogenic impulses and deleterious oncogenic stress. Human papillomavirus (HPV) infection is highly prevalent in
Externí odkaz:
https://doaj.org/article/8b5f52579e3f46898730b41cc411901e
Autor:
Matheus H. Dias, Cecília S. Fonseca, Julianna D. Zeidler, Layra L. Albuquerque, Marcelo S. daSilva, Eduardo Cararo‐Lopes, Marcelo S. Reis, Vincent Noël, Edmilson O. dosSantos, Ian A. Prior, Hugo A. Armelin
Publikováno v:
Molecular Oncology, Vol 13, Iss 2, Pp 290-306 (2019)
In malignant transformation, cellular stress‐response pathways are dynamically mobilized to counterbalance oncogenic activity, keeping cancer cells viable. Therapeutic disruption of this vulnerable homeostasis might change the outcome of many human
Externí odkaz:
https://doaj.org/article/a0f2218e8b7245598d3649ce9e9b7bc0
Autor:
Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa
Supplementary Table 1 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4ba71128b7d5124591139e92b6084f
https://doi.org/10.1158/0008-5472.22374059
https://doi.org/10.1158/0008-5472.22374059
Autor:
Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa
Supplementary Figures 1-8 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514848a91f63cd0e2e0d45bdb51175ac
https://doi.org/10.1158/0008-5472.22374062
https://doi.org/10.1158/0008-5472.22374062
Autor:
Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa
Fibroblast growth factor 2 (FGF2) is considered to be a bona fide oncogenic factor, although results from our group and others call this into question. Here, we report that exogenous recombinant FGF2 irreversibly inhibits proliferation by inducing se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df18ccea0863a760d7c022c9cf65eed7
https://doi.org/10.1158/0008-5472.c.6497321
https://doi.org/10.1158/0008-5472.c.6497321
Autor:
Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa
Supplementary Figure Legends 1-8 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5953fad9222df4f80db09aff5e10e498
https://doi.org/10.1158/0008-5472.22374065.v1
https://doi.org/10.1158/0008-5472.22374065.v1
Autor:
Eduardo Cararo-Lopes, Matheus H. Dias, Marcelo S. da Silva, Julianna D. Zeidler, Alexandre T. Vessoni, Marcelo S. Reis, Enrique Boccardo, Hugo A. Armelin
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41419-021-03564-4
Externí odkaz:
https://doaj.org/article/ec192d0da80846c8b5640aabfe8ddce9
Autor:
Matheus Henrique Dias, Anoek Friskes, Siying Wang, Joao M. Fernandes Neto, Frank van Gemert, Soufiane Mourragui, Hendrik J. Kuiken, Sara Mainardi, Daniel Alvarez-Villanueva, Cor Lieftink, Ben Morris, Anna Dekker, Emma van Dijk, Chrysa Papagianni, Marcelo S. da Silva, Robin Jansen, Antonio Mulero-Sánchez, Elke Malzer, August Vidal, Cristina Santos, Ramón Salazar, Rosangela A. M. Wailemann, Thompson E. P. Torres, Giulia De Conti, Jonne A. Raaijmakers, Petur Snaebjornsson, Shengxian Yuan, Wenxin Qin, John S. Kovach, Hugo A. Armelin, Hein te Riele, Alexander van Oudenaarden, Haojie Jin, Roderick L. Beijersbergen, Alberto Villanueva, Rene H. Medema, Rene Bernards
Cancer homeostasis depends on a balance between activated oncogenic pathways driving tumorigenesis and engagement of stress-response programs that counteract the inherent toxicity of such aberrant signaling. While inhibition of oncogenic signaling pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a1e3875a49631c0a488ddbe547c772b
https://doi.org/10.1101/2023.02.06.527335
https://doi.org/10.1101/2023.02.06.527335
Autor:
Fabio Montoni, Ronaldo N. de Sousa, Marcelo B. L. Junior, Cristiano G. S. Campos, Vivian M. Constantino, Willian Wang, Cássia S. Sanctos, Hugo A. Armelin, Marcelo S. Reis
Publikováno v:
Anais do XVI Brazilian e-Science Workshop (BRESCI 2022).
Over the years, several tools have been developed with the aim of recreating signaling pathways, allowing the in silico representation of a biological system to be glimpsed from afar, which would improve disease studies. However, despite all the prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23afbf367508188deffd994869b75a1a
https://doi.org/10.5753/bresci.2022.222789
https://doi.org/10.5753/bresci.2022.222789
Autor:
Ricardo Pariona-Llanos, Raphael Souza Pavani, Marcelo Reis, Vincent Noël, Ariel Mariano Silber, Hugo Aguirre Armelin, Maria Isabel Nogueira Cano, Maria Carolina Elias
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120896 (2015)
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a classical metabolic enzyme involved in energy production and plays a role in additional nuclear functions, including transcriptional control, recognition of misincorporated nucleotides in DNA and
Externí odkaz:
https://doaj.org/article/501fc9cdcbad47f1bf37e67cd7afe7e1