Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Hugo, Botha"'
Autor:
Pragalv Karki, Stephanie Sincomb, Matthew C. Murphy, Jeffrey L. Gunter, Matthew L. Senjem, Jonathan Graff-Radford, David T. Jones, Hugo Botha, Jeremy K. Cutsforth-Gregory, Benjamin D. Elder, John Huston, III, Petrice M. Cogswell
Publikováno v:
Brain Multiphysics, Vol 7, Iss , Pp 100101- (2024)
Background and purpose: Idiopathic normal pressure hydrocephalus (iNPH) is a cerebrospinal fluid (CSF) dynamics disorder as evidenced by the delayed ascent of radiotracers over the cerebral convexity on radionuclide cisternography. However, the exact
Externí odkaz:
https://doaj.org/article/21e0c4ca01464a188084e7be2da6d51c
Autor:
Kevin A. Mazurek, Leland Barnard, Hugo Botha, Teresa Christianson, Jonathan Graff-Radford, Ronald Petersen, Prashanthi Vemuri, B. Gwen Windham, David T. Jones, Farwa Ali
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Digital quantification of gait can be used to measure aging- and disease-related decline in mobility. Gait performance also predicts prognosis, disease progression, and response to therapies. Most gait analysis systems require large amounts
Externí odkaz:
https://doaj.org/article/465e6866d8d6451c8cc4ebc456834d5a
Autor:
Kevin A. Mazurek, Ph.D., Leland Barnard, Ph.D., Hugo Botha, M.B., Ch.B., Teresa Christianson, Jonathan Graff-Radford, M.D., David T. Jones, M.D., David S. Knopman, M.D., Ronald C. Petersen, M.D., Ph.D., Prashanthi Vemuri, Ph.D., Clifford R. Jack, Jr., M.D., Farwa Ali, M.B.B.S.
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 3, Pp 491- (2024)
Externí odkaz:
https://doaj.org/article/6c58504e92cc4442a4ec4b007fa37d15
Autor:
Elijah Mak, Robert I. Reid, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Sheelakumari Raghavan, Prashanthi Vemuri, Clifford R. Jack, Hoon Ki Min, Manoj K. Jain, Toji Miyagawa, Leah K. Forsberg, Julie A. Fields, Rodolfo Savica, Jonathan Graff-Radford, David T. Jones, Hugo Botha, Erik K. St. Louis, David S. Knopman, Vijay K. Ramanan, Dennis W. Dickson, Neill R. Graff-Radford, Tanis J. Ferman, Ronald C. Petersen, Val J. Lowe, Bradley F. Boeve, John T. O’Brien, Kejal Kantarci
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white matter tissue microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI)
Externí odkaz:
https://doaj.org/article/149702719cdf4981a0894fd359d25ace
Publikováno v:
NeuroImage, Vol 286, Iss , Pp 120509- (2024)
Purpose: The pattern of flortaucipir tau PET uptake is topographically similar to the pattern of magnetic susceptibility in progressive supranuclear palsy (PSP); both with increased signal in subcortical structures such as the basal ganglia and midbr
Externí odkaz:
https://doaj.org/article/ad5d4b38537c4e9ba93c3d10a5a5aacd
Autor:
Neha Singh-Reilly, Hugo Botha, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Mary M. Machulda, Jonathan Graff-Radford, Christopher G. Schwarz, Ronald C. Petersen, Val J. Lowe, Clifford R. Jack, Jr, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103639- (2024)
Primary progressive aphasia (PPA) variants present with distinct disruptions in speech-language functions with little known about the interplay between affected and spared regions within the speech-language network and their interaction with other fu
Externí odkaz:
https://doaj.org/article/67ce0fdfcf9a4894abf06efac9019079
Autor:
Rodolfo G. Gatto, Gabriela Meade, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Hugo Botha, Mary M. Machulda, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
Brain and Behavior, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background Progressive apraxia of speech (PAOS) is characterized by difficulties with motor speech programming and planning. PAOS targets gray matter (GM) and white matter (WM) microstructure that can be assessed using diffusion tensor imagi
Externí odkaz:
https://doaj.org/article/76e850b7928443e58ea7ca7b4898c7b1
Autor:
Nick Corriveau-Lecavalier, Leland R. Barnard, Scott A. Przybelski, Venkatsampath Gogineni, Hugo Botha, Jonathan Graff-Radford, Vijay K. Ramanan, Leah K. Forsberg, Julie A. Fields, Mary M. Machulda, Rosa Rademakers, Ralitza H. Gavrilova, Maria I. Lapid, Bradley F. Boeve, David S. Knopman, Val J. Lowe, Ronald C. Petersen, Clifford R. Jack, Kejal Kantarci, David T. Jones
Publikováno v:
NeuroImage: Clinical, Vol 41, Iss , Pp 103559- (2024)
Genetic mutations causative of frontotemporal lobar degeneration (FTLD) are highly predictive of a specific proteinopathy, but there exists substantial inter-individual variability in their patterns of network degeneration and clinical manifestations
Externí odkaz:
https://doaj.org/article/70c787dd63d643fea9b1dbdf0ec4a2cf
Autor:
Rebecca R. Valentino, Chloe Ramnarine, Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto-Beasley, Ronald L. Walton, Shunsuke Koga, Koji Kasanuki, Melissa E. Murray, Ryan J. Uitti, Julie A. Fields, Hugo Botha, Vijay K. Ramanan, Kejal Kantarci, Val J. Lowe, Clifford R. Jack, Nilufer Ertekin-Taner, Rodolfo Savica, Jonathan Graff-Radford, Ronald C. Petersen, Joseph E. Parisi, R. Ross Reichard, Neill R. Graff-Radford, Tanis J. Ferman, Bradley F. Boeve, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Dementia with Lewy bodies (DLB) is clinically diagnosed when patients develop dementia less than a year after parkinsonism onset. Age is the primary risk factor for DLB and mitochondrial health influences ageing through effective oxidative p
Externí odkaz:
https://doaj.org/article/3ccebbf408344276a4d599bfa2266e82
Autor:
Sheelakumari Raghavan, Scott A. Przybelski, Robert I. Reid, Timothy G. Lesnick, Vijay K. Ramanan, Hugo Botha, Billie J. Matchett, Melissa E. Murray, R. Ross Reichard, David S. Knopman, Jonathan Graff-Radford, David T. Jones, Val J. Lowe, Michelle M. Mielke, Mary M. Machulda, Ronald C. Petersen, Kejal Kantarci, Jennifer L. Whitwell, Keith A. Josephs, Clifford R. Jack, Prashanthi Vemuri
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Multi-compartment modelling of white matter microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI) can provide information on white matter health through neurite density index and free water measures. We hypothesized
Externí odkaz:
https://doaj.org/article/688e5b6e71234dd09762d60ffedd3aa6