Evolution of patient demographics, baseline clinical characteristics and outcomes in Phase 3 trials of biologics (TNFi, IL12/23i, IL17i, IL23i), PDE4i and TYK2i for psoriasis

Autor: Sara Peeters, Kurt De Vlam, Hugo Boonen, Canan Güvenç, Tom Hillary

Publikováno v: JEADV Clinical Practice, Vol 3, Iss 2, Pp 547-564 (2024)

Abstract Background Psoriasis, a common chronic inflammatory skin disease with major impact on quality of life, is associated with several comorbidities. A better understanding of the pathogenesis of psoriasis has led to the development and approval

Externí odkaz: https://doaj.org/article/08fc66fd6dfa49bebc68b3e59ddcb913

A Belgian consensus on the definition of a treat-to-target outcome set in psoriasis management

Autor: Grine, L, de la Brassinne, M, Ghislain, P-D, Hillary, T, Lambert, J, Segaert, S, Willaert, F, Farida, Benhadou, Chantal, Bonardeaux, Hugo, Boonen, Audrey, Henno, Sven, Lanssens, Arjen, Nikkels F, Annelies, Stockman, Erwin, Suys, Linda, Temmerman, Mark, Vandaele, Karen, Vermeersch

Publikováno v: Journal of the European Academy of Dermatology and Venereology
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Journal of the European Academy of Dermatology and Venereology, Vol. 34, no. 4, p. 676-684 (2020)

OBJECTIVE: Treat-to-target (T2T) is an algorithm to reach a predefined outcome. Here, we define a T2T outcome for moderate-to-severe psoriasis vulgaris. METHODS: Briefly, the study included a literature review, discussions with key opinion leaders, r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2112f6dc38bae8badbc14a92342648c9
https://lirias.kuleuven.be/handle/20.500.12942/694761

Real-life practice study of the clinical outcome and cost-effectiveness of photodynamic therapy using methyl aminolevulinate (MAL-PDT) in the management of actinic keratosis and basal cell carcinoma

Autor: Lieven, Annemans, Karin, Caekelbergh, Rik, Roelandts, Hugo, Boonen, Christoph, Leys, Arjen F, Nikkels, V, van Den Haute, L, van Quickenborne, Evelien, Verhaeghe, Bernard, Leroy

Publikováno v: European journal of dermatology : EJD. 18(5)

Clinical trials have shown that photodynamic therapy using methyl aminolevulinate (MAL-PDT) is an effective treatment for actinic keratosis (AK), and nodular and superficial basal cell carcinoma (nBCC and sBCC) unsuitable for other available therapie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0f0f29c8094b71370339a1f6a3c77bdc
https://pubmed.ncbi.nlm.nih.gov/18693157

Dysplastic nevus syndrome: ultraviolet hypermutability confirmed in vitro by elevated sister chromatid exchanges

Autor: Hugo Boonen, Elisabeth Bohnert, Ernst G. Jung

Publikováno v: Dermatologica. 173(6)

The dysplastic nevus syndrome (DNS) is a clinical and genetic entity in which affected individuals have increased numbers of dysplastic nevi and a markedly increased risk of developing one or more cutaneous melanomas. Sister chromatid exchanges (SCE)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348a68642419841729cbf1821c780244
https://pubmed.ncbi.nlm.nih.gov/3817241

Het gebruik van immuunmodulatoren bij psoriasis, een overzicht

Autor: Annelien, Jan Gutermuth, Eline Vandersteen, Hugo Boonen

Publikováno v: Vrije Universiteit Brussel

De laatste jaren wordt er veel aandacht besteed aan de ontwikkeling van nieuwe immuunmodulatoren als behandeling voor patiënten met ernstige psoriasis. Onder de immuunmodulatoren behoren zowel de Biologicals, humane monoclonale antistoffen die geric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8b704fb8d9ef07ae9aa19a0c1f15574d
https://researchportal.vub.be/en/publications/cc8d4ed7-b815-4c82-8427-314e26e5ae49