Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hugo, Alarcan"'
Autor:
Yara Al Ojaimi, Charlotte Slek, Samira Osman, Hugo Alarcan, Sylviane Marouillat, Philippe Corcia, Patrick Vourc'h, Débora Lanznaster, Hélène Blasco
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101664- (2024)
Amyotrophic Lateral Sclerosis (ALS) is the most common neurodegenerative disease affecting motor neurons. The pathophysiology of ALS is not well understood but TDP-43 proteinopathy (aggregation and mislocalization) is one of the major phenomena descr
Externí odkaz:
https://doaj.org/article/cda875ecf0304e528815c41960463213
Autor:
Hugo Alarcan, Mélanie Berthet, Laura Suire, Corentin Colas, Loïc Gonzalez, Christophe Paget, Isabelle Benz-de Bretagne, Eric Piver, Patrick Vourc'h, Christian Andres, Philippe Corcia, Hélène Blasco
Publikováno v:
SLAS Technology, Vol 27, Iss 5, Pp 327-334 (2022)
There is currently no diagnostic or prognostic biomarker available in clinical practice for Amyotrophic Lateral Sclerosis (ALS). The objective of this study was to monitor a combination of various inflammatory markers, lipids, and apolipoproteins alt
Externí odkaz:
https://doaj.org/article/4b0344ff01fa407e8e2260af0b16eab3
Autor:
Camille Cotet, Hugo Alarcan, Olivier Hérault, Philippe Corcia, Patrick Vourc’h, Christian R. Andres, Hélène Blasco, Charlotte Veyrat-Durebex
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1689 (2023)
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative motor neuron disease and remains misunderstood with a difficult diagnosis and prognosis. The implication of the immune system is recognized in ALS pathophysiology, hence the int
Externí odkaz:
https://doaj.org/article/8d2b5fc435154f429d48bb22e85a0ac4
Autor:
Hugo Alarcan, Camille Cotet, Nadège Lépine, Julie Morel, Patrick Vourc'h, Christian Andres, Philippe Corcia, Hélène Blasco
Publikováno v:
European Journal of Neurology. 30:1611-1618
Autor:
Hugo Alarcan, Pauline Cannet, Vincent Camus, Guillaume Fond, Xavier Zendjidjian, Romain Guilhaumou, Sylvie Quaranta
Publikováno v:
British Journal of Clinical Pharmacology. 89:1665-1671
Cytochrome P450 1A2 (CYP1A2) is involved in the metabolism of antipsychotic drugs such as clozapine and olanzapine. Personalization of these treatments requires an accurate estimation of CYP1A2 activity. In this study, we aimed (1) to evaluate the co
Autor:
Blasco, Hugo Alarcan, Patrick Vourc’h, Lise Berton, Isabelle Benz-De Bretagne, Eric Piver, Christian R. Andres, Philippe Corcia, Charlotte Veyrat-Durebex, Hélène
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 11196
Central nervous system (CNS) barrier impairment has been reported in amyotrophic lateral sclerosis (ALS), highlighting its potential significance in the disease. In this context, we aim to shed light on its involvement in the disease, by determining
Autor:
Hugo Alarcan, David Schnell, Stéphane Rouleau, Anissa Chachia, Franck Saint-Marcoux, Olivier Mathieu, Sylvain Couderc
Publikováno v:
Therapies. 77:603-609
Autor:
Hugo Alarcan, Romane Chaumond, Patrick Emond, Isabelle Benz-De Bretagne, Antoine Lefèvre, Salah-eddine Bakkouche, Charlotte Veyrat-Durebex, Patrick Vourc’h, Christian Andres, Philippe Corcia, Hélène Blasco
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 691 (2021)
The aim of this study was to evaluate the kynurenine pathway (KP) and amino acids profile, using mass spectrometry, in the cerebrospinal fluid (CSF) of 42 amyotrophic lateral sclerosis (ALS) patients at the diagnosis and 40 controls to detect early d
Externí odkaz:
https://doaj.org/article/a2f01e361ff64404a9f020876d756809
Publikováno v:
Actualités Pharmaceutiques. 61:27-30
Autor:
Jean-Baptiste Delaye, Hugo Alarcan, Nicolas Vallet, Charlotte Veyrat-Durebex, Louis Bernard, Olivier Hérault, Martine Ropert, Julien Marlet, Emmanuel Gyan, Christian Andres, Hélène Blasco, Eric Piver
Publikováno v:
Journal of Investigative Medicine. 70:934-938
Iron metabolism is tightly linked to infectious and inflammatory signals through hepcidin synthesis. To date, iron homeostasis during SARS-CoV-2 infection has not yet been described. The aim of this study is to characterize the hepcidin and erythroid