Immune Sensing of Candida Albicans Requires Cooperative Recognition of Mannans and Glucans by Lectin and Toll-Like Receptors

Autor: Netea, Mihai, Gow, Neil A.R., Munro, Carol A., Bates, Steven, Collins, Claire, Ferwerda, Gerben, Hobson, Richard P., Bertram, Gwyneth, Hughes, H. Bleddyn, Jansen, Trees, Jacobs, Liesbeth, Buurman, Ed T., Gijzen, Karlijn, Williams, David L., Torensma, Ruurd, McKinnon, Alistair, MacCallum, Donna M., Odds, Frank C., Van Der Meer, Jos W.M., Brown, Alistair J.P., Kullberg, Bart Jan

Publikováno v: ETSU Faculty Works.

The fungal pathogen Candida albicans has a multilayered cell wall composed of an outer layer of proteins glycosylated with N- or O-linked mannosyl residues and an inner skeletal layer of β-glucans and chitin. We demonstrate that cytokine production

Externí odkaz: https://dc.etsu.edu/etsu-works/18096

Outer Chain N-Glycans Are Required for Cell Wall Integrity and Virulence of Candida albicans.

Autor: Bates, Steven¹, Hughes, H. Bleddyn¹, Munro, Carol A.¹, Thomas, William P. H.¹, MacCallum, Donna M.¹, Bertram, Gwyneth¹, Atrih, Abdelmadjid², Ferguson, Michael A. J.², Brown, Alistair J. P.¹, Odds, Frank C.¹, Gow, Neil A. R.¹ n.gow@abdn.ac.uk

Publikováno v: Journal of Biological Chemistry. 1/6/2006, Vol. 281 Issue 1, p90-98. 9p. 2 Black and White Photographs, 4 Diagrams, 4 Charts, 3 Graphs.

Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors.

Autor: Netea, Mihai G.^1,2 m.netea@aig.umcn.nl, Gow, Neil A. R.³, Munro, Carol A.³, Bates, Steven³, Collins, Claire³, Ferwerda, Gerben^1,2, Hobson, Richard P.³, Bertram, Gwyneth³, Hughes, H. Bleddyn³, Jansen, Trees^1,2, Jacobs, Liesbeth^1,2, Buurman, Ed T.³, Gijzen, Karlijn⁴, Williams, David L.⁵, Torensma, Ruurd⁴, McKinnon, Alistair³, MacCallum, Donna M.³, Odds, Frank C.³, Van der Meer, Jos W. M.^1,2, Brown, Alistair J. P.³

Publikováno v: Journal of Clinical Investigation. Jun2006, Vol. 116 Issue 6, p1642-1650. 9p. 1 Diagram, 6 Graphs.

Mnt1p and Mnt2p of Candida albicans Are Partially Redundant α-1,2-Mannosyltransferases That Participate in O-Linked Mannosylation and Are Required for Adhesion and Virulence.

Autor: Munro, Carol A.¹, Bates, Steven¹, Buurman, Ed T.¹, Hughes, H. Bleddyn¹, MacCallum, Donna M.¹, Bertram, Gwyneth¹, Atrih, Abdel², Ferguson, Michael A. J.², Bain, Judith M.¹, Brand, Alexandra¹, Hamilton, Suzanne¹, Westwater, Caroline¹, Thomson, Lynn M.¹, Brown, Alistair J. P.¹, Odds, Frank C.¹, Gow, Neil A. R.¹ n.gow@abdn.ac.uk

Publikováno v: Journal of Biological Chemistry. 1/14/2005, Vol. 280 Issue 2, p1051-1060. 10p. 8 Diagrams, 3 Charts, 2 Graphs.

CHS8-a fourth chitin synthase gene of Candida albicans contributes to in vitro chitin synthase activity, but is dispensable for growth.

Autor: Munro CA; Department of Molecular and Cell Biology, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, UK., Whitton RK, Hughes HB, Rella M, Selvaggini S, Gow NA

Publikováno v: Fungal genetics and biology : FG & B [Fungal Genet Biol] 2003 Nov; Vol. 40 (2), pp. 146-58.