Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Hugh Y. Rienhoff"'
Autor:
Iain W. Chalmers, Christoph Grunau, Josephine Forde-Thomas, Karl F. Hoffmann, Andrea Brancale, Cassandra A. Celatka, Gilda Padalino, Jay H. Kalin, Hugh Y. Rienhoff Jr., Damien Lassalle, Philip A. Cole
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: Schistosoma mansoni, a parasitic worm species responsible for the neglected tropical disease schistosomiasis, undergoes strict developmental regulation of gene expression that is carefully controlled by both genetic and epigenetic process
Externí odkaz:
https://doaj.org/article/4dd3f4ccaedf4ebd9cfa3454b89491e8
Autor:
Jonas S. Jutzi, Maria Kleppe, Jennifer Dias, Hans Felix Staehle, Kaitlyn Shank, Julie Teruya-Feldstein, Sudheer Madan Mohan Gambheer, Christine Dierks, Hugh Y. Rienhoff, Jr, Ross L. Levine, Heike L. Pahl
Publikováno v:
HemaSphere, Vol 2, Iss 3 (2018)
Abstract. Despite recent advances, the myeloproliferative neoplasms (MPNs) are attended by considerable morbidity and mortality. Janus kinase (Jak) inhibitors such as ruxolitinib manage symptoms but do not substantially change the natural history of
Externí odkaz:
https://doaj.org/article/9a5226cfef28450b8b2347a82de72292
Autor:
Joseph B. Hiatt, Holly Sandborg, Sarah M. Garrison, Henry U. Arnold, Sheng-You Liao, Justin P. Norton, Travis J. Friesen, Feinan Wu, Kate D. Sutherland, Hugh Y. Rienhoff, Renato Martins, A. McGarry Houghton, Shivani Srivastava, David MacPherson
Publikováno v:
Clin Cancer Res
Purpose: The addition of immune checkpoint blockade (ICB) to platinum/etoposide chemotherapy changed the standard of care for small cell lung cancer (SCLC) treatment. However, ICB addition only modestly improved clinical outcomes, likely reflecting t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8701d652d8cb975df25a96dd599ab10e
https://doi.org/10.1158/1078-0432.ccr-22-1128
https://doi.org/10.1158/1078-0432.ccr-22-1128
Autor:
Scott A. Armstrong, Ross L. Levine, Anthony Letai, Hugh Y. Rienhoff, Scott W. Lowe, Timour Baslan, Johannes Zuber, Helen S. Tian, Madison Rex, Mitali Kini, Vidushi Durani, Nicole L. DelGaudio, Keith B. Cordner, Lihua Zou, Chun-Wei Chen, Chun-Hao Huang, Monica Cusan, Christopher A. Famulare, Filiz Sen, Martin S. Tallman, Eytan M. Stein, Jacob L. Glass, Richard P. Koche, Salma Parvin, Aaron D. Goldberg, S. Haihua Chu, Sheng F. Cai
shRNA screen hits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef0859770e92c8c152395bdc4620b8d
https://doi.org/10.1158/2159-8290.22536416.v1
https://doi.org/10.1158/2159-8290.22536416.v1
Autor:
Scott A. Armstrong, Ross L. Levine, Anthony Letai, Hugh Y. Rienhoff, Scott W. Lowe, Timour Baslan, Johannes Zuber, Helen S. Tian, Madison Rex, Mitali Kini, Vidushi Durani, Nicole L. DelGaudio, Keith B. Cordner, Lihua Zou, Chun-Wei Chen, Chun-Hao Huang, Monica Cusan, Christopher A. Famulare, Filiz Sen, Martin S. Tallman, Eytan M. Stein, Jacob L. Glass, Richard P. Koche, Salma Parvin, Aaron D. Goldberg, S. Haihua Chu, Sheng F. Cai
Bliss synergy scores for in vitro venetoclax/IMG-7289 combination treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c67d11667513f9cb4d92e31f8616ee
https://doi.org/10.1158/2159-8290.22536413
https://doi.org/10.1158/2159-8290.22536413
Autor:
Scott A. Armstrong, Ross L. Levine, Anthony Letai, Hugh Y. Rienhoff, Scott W. Lowe, Timour Baslan, Johannes Zuber, Helen S. Tian, Madison Rex, Mitali Kini, Vidushi Durani, Nicole L. DelGaudio, Keith B. Cordner, Lihua Zou, Chun-Wei Chen, Chun-Hao Huang, Monica Cusan, Christopher A. Famulare, Filiz Sen, Martin S. Tallman, Eytan M. Stein, Jacob L. Glass, Richard P. Koche, Salma Parvin, Aaron D. Goldberg, S. Haihua Chu, Sheng F. Cai
The cell of origin of oncogenic transformation is a determinant of therapeutic sensitivity, but the mechanisms governing cell-of-origin–driven differences in therapeutic response have not been delineated. Leukemias initiating in hematopoietic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c5021d4d800470cc3b706b15675c4c7
https://doi.org/10.1158/2159-8290.c.6548138.v1
https://doi.org/10.1158/2159-8290.c.6548138.v1
Autor:
Scott A. Armstrong, Ross L. Levine, Anthony Letai, Hugh Y. Rienhoff, Scott W. Lowe, Timour Baslan, Johannes Zuber, Helen S. Tian, Madison Rex, Mitali Kini, Vidushi Durani, Nicole L. DelGaudio, Keith B. Cordner, Lihua Zou, Chun-Wei Chen, Chun-Hao Huang, Monica Cusan, Christopher A. Famulare, Filiz Sen, Martin S. Tallman, Eytan M. Stein, Jacob L. Glass, Richard P. Koche, Salma Parvin, Aaron D. Goldberg, S. Haihua Chu, Sheng F. Cai
Supplemental Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576108361133b2788982c2e7fea52dd6
https://doi.org/10.1158/2159-8290.22536419.v1
https://doi.org/10.1158/2159-8290.22536419.v1
Autor:
David MacPherson, Shivani Srivastava, A. McGarry Houghton, Renato Martins, Hugh Y. Rienhoff, Kate D. Sutherland, Feinan Wu, Travis J. Friesen, Justin P. Norton, Sheng-You Liao, Henry U. Arnold, Sarah M. Garrison, Holly Sandborg, Joseph B. Hiatt
Purpose:The addition of immune checkpoint blockade (ICB) to platinum/etoposide chemotherapy changed the standard of care for small cell lung cancer (SCLC) treatment. However, ICB addition only modestly improved clinical outcomes, likely reflecting th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d029b71b7ed5b054576af608f27cdf
https://doi.org/10.1158/1078-0432.c.6532733.v1
https://doi.org/10.1158/1078-0432.c.6532733.v1
Autor:
David MacPherson, Shivani Srivastava, A. McGarry Houghton, Renato Martins, Hugh Y. Rienhoff, Kate D. Sutherland, Feinan Wu, Travis J. Friesen, Justin P. Norton, Sheng-You Liao, Henry U. Arnold, Sarah M. Garrison, Holly Sandborg, Joseph B. Hiatt
Supplementary Figure from Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0598cb709fc1b05db39745388fe770f9
https://doi.org/10.1158/1078-0432.22488479
https://doi.org/10.1158/1078-0432.22488479
Autor:
Gilda Padalino, Cassandra A. Celatka, Hugh Y. Rienhoff Jr., Jay H. Kalin, Philip A. Cole, Damien Lassalle, Josephine Forde-Thomas, Iain W. Chalmers, Andrea Brancale, Christoph Grunau, Karl F. Hoffmann
Publikováno v:
Wellcome Open Research. 8:146
Background: Schistosoma mansoni, a parasitic worm species responsible for the neglected tropical disease schistosomiasis, undergoes strict developmental regulation of gene expression that is carefully controlled by both genetic and epigenetic process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5629d44c9e2a514efa9d9bb1e48a949b
https://doi.org/10.12688/wellcomeopenres.18826.1
https://doi.org/10.12688/wellcomeopenres.18826.1