Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Hugh Salamon"'
Autor:
Natalie Bruiners, Noton K. Dutta, Valentina Guerrini, Hugh Salamon, Ken D. Yamaguchi, Petros C. Karakousis, Maria L. Gennaro
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1617-1628 (2020)
The rise of drug-resistant tuberculosis poses a major risk to public health. Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase anti-tubercular antibiotic efficacy in animal model
Externí odkaz:
https://doaj.org/article/75876116b6df464f8fdbaf48363dccfd
Autor:
Valentina Guerrini, Brendan Prideaux, Landry Blanc, Natalie Bruiners, Riccardo Arrigucci, Sukhwinder Singh, Hsin Pin Ho-Liang, Hugh Salamon, Pei-Yu Chen, Karim Lakehal, Selvakumar Subbian, Paul O'Brien, Laura E Via, Clifton E Barry, Véronique Dartois, Maria Laura Gennaro
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007223 (2018)
Foam cells are lipid-laden macrophages that contribute to the inflammation and tissue damage associated with many chronic inflammatory disorders. Although foam cell biogenesis has been extensively studied in atherosclerosis, how these cells form duri
Externí odkaz:
https://doaj.org/article/3747bcd88e6540c69d80b16441707b17
Publikováno v:
Emerging Infectious Diseases, Vol 4, Iss 2, Pp 159-168 (1998)
Molecular epidemiologic studies of infectious diseases rely on pathogen genotype comparisons, which usually yield patterns comprising sets of DNA fragments (DNA fingerprints). We use a highly developed genotyping system, IS6110-based restriction frag
Externí odkaz:
https://doaj.org/article/b62235fa529b41c1a83ab90fae9edc7f
Autor:
Masaaki Toda, Zhifei Shao, Ken D Yamaguchi, Takehiro Takagi, Corina N D'Alessandro-Gabazza, Osamu Taguchi, Hugh Salamon, Lawrence L K Leung, Esteban C Gabazza, John Morser
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72392 (2013)
Previously we have shown in a mouse model of bronchial asthma that thrombomodulin can convert immunogenic conventional dendritic cells into tolerogenic dendritic cells while inducing its own expression on their cell surface. Thrombomodulin(+) dendrit
Externí odkaz:
https://doaj.org/article/26e3ed63295d422090cb4d1fac1eb183
Autor:
Ashutosh Lal, Christian López-Peña, Gunmeet Bali, Cassandra D Calloway, Hugh Salamon, Katie T. Carlberg, Henry A. Erlich, Shelly Shih, Ken D. Yamaguchi, Reena Das
Publikováno v:
The Journal of Applied Laboratory Medicine. 7:515-531
Background Noninvasive prenatal testing (NIPT) of chromosomal aneuploidies based on next-generation sequencing (NGS) analysis of fetal DNA in maternal plasma is well established, but testing for autosomal recessive disorders remains challenging. NGS
Autor:
Maria Laura Gennaro, Petros C. Karakousis, Valentina Guerrini, Hugh Salamon, Natalie Bruiners, Ken D. Yamaguchi, Noton K. Dutta
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 61, Iss 12, Pp 1617-1628 (2020)
Journal of Lipid Research, Vol 61, Iss 12, Pp 1617-1628 (2020)
The rise of drug-resistant tuberculosis poses a major risk to public health. Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase anti-tubercular antibiotic efficacy in animal model
Autor:
Petros C. Karakousis, Valentina Guerrini, Maria Laura Gennaro, Noton K. Dutta, Ken D. Yamaguchi, Hugh Salamon, Natalie Bruiners
Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase anti-tubercular antibiotic efficacy in animal models. We investigated the mechanism of anti-tubercular action of simvastatin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44971232a7c3be05ed7cf9e760b85913
https://doi.org/10.1101/2020.03.04.977579
https://doi.org/10.1101/2020.03.04.977579
Autor:
Valentina Guerrini, Petros C. Karakousis, Maria Laura Gennaro, Noton K. Dutta, Ken D. Yamaguchi, Hugh Salamon, Natalie Bruiners
Publikováno v:
SSRN Electronic Journal.
Background: Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase the efficacy of anti-tubercular antibiotics in animal models. A previous report proposed that the anti-tubercular ac
Autor:
Ken D. Yamaguchi, Hugh Salamon, Janani Ravi, Lanbo Shi, Richard Pine, Natalie Bruiners, Karim Lakehal, Maria Laura Gennaro
Publikováno v:
The Journal of Immunology. 193:30-34
Vitamin D has long been linked to resistance to tuberculosis, an infectious respiratory disease that is increasingly hard to treat because of multidrug resistance. Previous work established that vitamin D induces macrophage antimicrobial functions ag
Autor:
Rosemary Sweetwood, Hugh Salamon, Cameron R. Cunningham, Sariah A. Kell, Edith M. Hessel, John D. Campbell, Robert L. Coffman, Clare M. Lloyd, Mabel Chu, Jeremy A. Lum, HM Kozy
Publikováno v:
Thorax. 69:565-573
Background CpG-containing oligodeoxynucleotides (CpG-ODNs) are potent inhibitors of T helper 2 mediated allergic airway disease in sensitised mice challenged with allergen. A single treatment has transient effects but a limited series of treatments h