Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Hugh O. McDevitt"'
Autor:
Hugh O. McDevitt, Christian Boitard
Publikováno v:
Perspectives on Autoimmunity ISBN: 9780429282324
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebe893ea1348b28eb83eae9945a5b6bb
https://doi.org/10.1201/9780429282324-3
https://doi.org/10.1201/9780429282324-3
Autor:
K. Itakura, Takehiko Sasazuki, Hugh O. McDevitt, Andrew J. McMichael, Akemi Wakisaka, H. Yakura, Miki Aizawa, Rose Payne
Publikováno v:
Tissue Antigens. 9:62-65
A new HLA-D specificity was found in the Japanese population in two different laboratories. Japanese cell YT, found at Stanford, California, was A9,BW22J,CW1 and cell Wa, found at Sapporo, Japan, was A9,BW22J homozygous. They were shown to be HLA-D i
Autor:
Sara A. Michie, Kathleen H. Rubins, Robert D. Schreriber, Hugh O. McDevitt, Qing Li, Baohui Xu
Publikováno v:
Proceedings of the National Academy of Sciences. 105:12439-12444
With the goal of identifying changes in gene expression in CD4 + T cells during the development of diabetes in the nonobese diabetic (NOD) mouse, we used DNA microarrays to analyze gene expression in CD4 + T cells from the pancreatic draining lymph n
Autor:
Judith A. Shizuru, Georg F. Beilhack, Rodolfo José Chaparro, Yueh-hsiu Chien, Hugh O. McDevitt, Yves Konigshofer
Publikováno v:
Proceedings of the National Academy of Sciences. 103:12475-12480
Before the onset of autoimmune destruction, type 1 diabetic patients and an animal model, the nonobese diabetic (NOD) mouse, show morphological and functional abnormalities in target organs, which may act as inciting events for leukocyte infiltration
Autor:
Hugh O. McDevitt
Publikováno v:
Immunology today. 2(8)
Autor:
Hugh O. McDevitt
Publikováno v:
Diabetes. 54:S4-S10
This presentation is an overview of mechanisms for developing and maintaining self-tolerance in mammalian organisms. Because this meeting is focused on type 1 diabetes and its mechanisms, the discussion deals primarily with mechanisms of T-cell toler
Autor:
Tsung-Hsien Chang, Shie-Liang Hsieh, Jen-Hsiang Liao, John T. Kung, Hugh O. McDevitt, Shu-Fen Wu, Hsiu-Ying Chang, Huey-Kang Sytwu, Yu-Chung Lin, Jung-Tung Hung
Publikováno v:
Journal of Autoimmunity. 25:181-192
To improve the feasibility of in vivo monitoring of autoreactive T cells in the diabetogenic process, we generated T1 and T2 doubly transgenic non-obese diabetic (NOD) mice in which transgenic human CD90 (hCD90) is simultaneously expressed on IFN-gam
Autor:
Sara A. Michie, Shannon J. Turley, Baohui Xu, Georg F. Beilhack, Hugh O. McDevitt, Li-Fen Lee, Tibor Warganich
Publikováno v:
Proceedings of the National Academy of Sciences. 102:15995-16000
TNF-α has been linked to the development of type 1 diabetes (T1D). We previously reported that neonatal treatment of nonobese diabetic (NOD) mice with TNF-α accelerated the onset of T1D, whereas TNF-α blockade in the same time period resulted in a