Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hugh Keeping"'
Autor:
Josh Appel, Hugh Keeping, Mark A. Palumbo, Phillip R. Lucas, Mauricio Valdes, Michael G. Ehrlich, Douglas C. Moore, Alex Robertson
Publikováno v:
The Spine Journal. 7:318-325
Background context The nonunion rate after posterolateral spinal fusion can be as high as 35%. This has stimulated interest in the development of techniques for enhancing new bone formation, including the addition of bioactive peptides or the use of
Publikováno v:
Bioelectromagnetics. 20:453-458
Recent information from several laboratories suggest that power frequency fields may stimulate cell differentiation in a number of model systems. In this way, they may be similar to pulsed electromagnetic fields, which have been used therapeutically.
Publikováno v:
Journal of Leukocyte Biology. 65:171-178
Interleukin-8 (IL-8) is an important mediator of neutrophil (PMN) function and the type A IL-8 receptor (IL-8RA) mediates these pro-inflammatory signals. Hypoxia or hypoxia/reoxygenation (H/R) affects the production of IL-8, but no data is available
Publikováno v:
Surgery. 124:409-417
Background: Neutrophil apoptosis is crucial in the resolution of inflammation. The role of interleukin (IL)-8 in neutrophil apoptosis has not been previously studied; we hypothesized that in addition to its role as a chemoattractant, IL-8 would regul
Publikováno v:
Surgery. 122:153-162
Background. Apoptosis is thought to be a central mechanism that leads to resolution of the inflammatory response. The regulation of polymorphonuclear leukocyte (PMN) apoptosis during hypoxia has not been previously characterized, and we hypothesized
Publikováno v:
Journal of Leukocyte Biology. 62:268-276
The role of polymorphonuclear leukocytes (PMN) in stemming systemic infection is executed mainly by the utilization of molecular O2 leading to the production of reactive oxygen intermediates (ROI). PMN-derived ROI also serve as intra- and extracellul
Publikováno v:
Surgery. 120:382-388
Background. The purpose of this study was to determine the effects of hypoxemia/reoxygenation (H/R) on the regulation of interleukin-8 (IL-8)-stimulated human polymorphonuclear neutrophil (PMN) bactericidal activity. Methods. Venous human whole blood
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 19(6)
This study was performed to investigate the effect of loading on the biology of newly forming bone during limb lengthening. Unilateral 2.0 mm femoral lengthenings were performed in 20 male Sprague Dawley rats. Half (n = 10) of the animals were allowe
Publikováno v:
The American journal of physiology. 272(4 Pt 1)
We investigated the effects of hypoxemia and hypoxemia-reoxygenation (H/R) on interleukin-8 (IL-8), tumor necrosis factor-alpha (TNF-alpha), or IL-1beta stimulation of whole blood polymorphonuclear leukocyte (PMN) phagocytosis and bactericidal activi
Publikováno v:
Surgery. 118(2)
Background. The purpose of these studies was to investigate the effect of hypoxemia on interleukin-8 (IL-8) regulation of phagocytosis and surface opsonic receptor expression of whole blood polymorphonuclear leukocytes (PMNs). Methods. Whole blood PM