Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hugh J. French"'
Autor:
Amanda Khoury, Joanna Achinger-Kawecka, Saul A. Bert, Grady C. Smith, Hugh J. French, Phuc-Loi Luu, Timothy J. Peters, Qian Du, Aled J. Parry, Fatima Valdes-Mora, Phillippa C. Taberlay, Clare Stirzaker, Aaron L. Statham, Susan J. Clark
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The architectural protein CTCF is a mediator of chromatin conformation, but how CTCF binding to DNA is regulated remains poorly understood. Here the authors find that there is a shared subset of CTCF-bound sites resistant to protein depletion in diff
Externí odkaz:
https://doaj.org/article/8b6198ec146c403090e434c6de6028fa
Autor:
Helen L. Lutgers, Brodie Sutcliffe, Rosanna Arnoldy, Clare Stirzaker, Susan J. van Dijk, Shalima S. Nair, Michael M. Swarbrick, Reginald V. Lord, Firoz Anwar, Peter L. Molloy, Elena Zotenko, Jenny Z. Song, Wenjia Qu, Susan J. Clark, Stephen T Bradford, Denis C. Bauer, Michael Buckley, Michelle Peranec, Hilal Varinli, Katherine Samaras, Aaron L. Statham, Julius Z. H. von Martels, Jason P. Ross, Madhavi P. Maddugoda, Timothy J. Peters, Hugh J. French
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, 9:9511. Nature Publishing Group
Scientific Reports
Scientific Reports, 9:9511. Nature Publishing Group
Scientific Reports
Adipocytes support key metabolic and endocrine functions of adipose tissue. Lipid is stored in two major classes of depots, namely visceral adipose (VA) and subcutaneous adipose (SA) depots. Increased visceral adiposity is associated with adverse hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab52944b338d30ee88efb302b757c62
https://doi.org/10.1038/s41598-019-45777-w
https://doi.org/10.1038/s41598-019-45777-w
Autor:
Susan J. Clark, Stephen T Bradford, Clare Stirzaker, Helen Speirs, Shalima S. Nair, Ruth Pidsley, Hugh J. French, Tim J Peters, Wenjia Qu, Terence P. Speed, Katherine A. Giles, Jenny Z. Song, Aaron L. Statham, Hilal Varinli
Publikováno v:
Bioinformatics
Motivation A synoptic view of the human genome benefits chiefly from the application of nucleic acid sequencing and microarray technologies. These platforms allow interrogation of patterns such as gene expression and DNA methylation at the vast major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94379b2957193270d9999f5b68a3d3d9
https://pubmed.ncbi.nlm.nih.gov/30084929
https://pubmed.ncbi.nlm.nih.gov/30084929
Autor:
Renea A. Taylor, Michelle Richards, Wenjia Qu, Aaron L. Statham, Preetika Balanathan, Birunthi Niranjan, Hugh J. French, Mark Frydenberg, Andrew Ryan, Elena Zotenko, Sam Norden, John Pedersen, Nicola J. Armstrong, Mitchell G. Lawrence, Clare Stirzaker, Lisa G. Horvath, Ruth Pidsley, Jenny Z. Song, Hieu T. Nim, Phillip D. Stricker, Melissa Papargiris, Hong Wang, Roman M. Chabanon, Roger J. Daly, Shalima S. Nair, James G. Kench, Gail P. Risbridger, Susan J. Clark, Tim J Peters
The growth and progression of solid tumors involves dynamic cross-talk between cancer epithelium and the surrounding microenvironment. To date, molecular profiling has largely been restricted to the epithelial component of tumors; therefore, features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd7f6fb6d81e8f0df8648b746f3862a
https://europepmc.org/articles/PMC5932604/
https://europepmc.org/articles/PMC5932604/
Autor:
Fatima Valdes-Mora, Clare Stirzaker, Nicola J. Armstrong, Ruth Pidsley, Qian Du, Aaron L. Statham, W Ng, Elena Zotenko, Hugh J. French, Warwick J. Locke, Susan J. Clark, Jenny Z. Song
Publikováno v:
Oncogene. 36(10)
Cancer is characterised by DNA hypermethylation and gene silencing of CpG island-associated promoters, including tumour-suppressor genes. The methyl-CpG-binding domain (MBD) family of proteins bind to methylated DNA and can aid in the mediation of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6d129a42d4f749c2a924eb572b8b53
https://pubmed.ncbi.nlm.nih.gov/27593931
https://pubmed.ncbi.nlm.nih.gov/27593931
Autor:
Ruth Pidsley, John Pedersen, Ola Larsson, Shalima S. Nair, Hugh J. French, Stuart John Ellem, Grant Buchanan, Renea A. Taylor, Mark Frydenberg, Gail P. Risbridger, Susan J. Clark, Aaron Stratham, Mitchell G. Lawrence, Luc Furic
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7e2137200ab22e41a60bb528168be2c
https://doi.org/10.1530/endoabs.37.oc8.5
https://doi.org/10.1530/endoabs.37.oc8.5
Publikováno v:
Bioinformatics
Summary: The initial steps in the analysis of next-generation sequencing data can be automated by way of software ‘pipelines’. However, individual components depreciate rapidly because of the evolving technology and analysis methods, often render
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353ba5b41cdaaf9eb448c8c10e77dfe4
https://doi.org/10.1093/bioinformatics/btu036
https://doi.org/10.1093/bioinformatics/btu036
Autor:
Kristine Hardy, Rohan B.H. Williams, M. Frances Shannon, Rosalind Attenborough, Hugh J. French
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 20(9-10)
Our knowledge of regulatory mechanisms of gene expression and other chromosomal processes related to DNA methylation and chromatin state is continuing to grow at a rapid pace. Understanding how these epigenomic phenomena vary between individuals will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e4b4aee330fbe28c52fc20d95d26b3
https://pubmed.ncbi.nlm.nih.gov/19763687
https://pubmed.ncbi.nlm.nih.gov/19763687