Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Hugh J, Clarke"'
Autor:
Abel Oppong, Yat Hei Leung, Anindya Ghosh, Marie-Line Peyot, Marilène Paquet, Carlos Morales, Hugh J. Clarke, Fahd Al-Mulla, Alexandre Boyer, S. R. Murthy Madiraju, Derek Boerboom, Cristian O'Flaherty, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102063- (2024)
Objectives: Obesity, diabetes and high-calorie diets are associated with defective sperm function and lowered male fertility. Mature spermatozoa primarily use fructose and glucose, and glucose and glycerol metabolism are important for sperm function.
Externí odkaz:
https://doaj.org/article/315c683a57974e74b09d44fa08f9ae3d
Publikováno v:
eLife, Vol 13 (2024)
Development of the mammalian oocyte requires physical contact with the surrounding granulosa cells of the follicle, which provide it with essential nutrients and regulatory signals. This contact is achieved through specialized filopodia, termed trans
Externí odkaz:
https://doaj.org/article/17a9b38352bf41f287035a338dc5f68c
Autor:
Laleh Abbassi, Stephany El-Hayek, Karen Freire Carvalho, Wusu Wang, Qin Yang, Sofia Granados-Aparici, Rafael Mondadori, Vilceu Bordignon, Hugh J. Clarke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Uncoupling of mature oocytes from somatic granulosa cells is required for their fertilization. Here the authors show that activation of EGFR signalling in granulosa cells during ovulation triggers ERK-dependent loss of filopodia oocyte adhesion, and
Externí odkaz:
https://doaj.org/article/348d0733017a4b4c8fcd9963a3acfe35
Autor:
Karl-Frédéric Vieux, Hugh J. Clarke
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract In many cell types, the length of the poly(A) tail of an mRNA is closely linked to its fate - a long tail is associated with active translation, a short tail with silencing and degradation. During mammalian oocyte development, two contrastin
Externí odkaz:
https://doaj.org/article/88be864bde564d92b1c953d226a7f749
Autor:
Flora Crozet, Gaëlle Letort, Rose Bulteau, Christelle Da Silva, Adrien Eichmuller, Anna Francesca Tortorelli, Joséphine Blévinal, Morgane Belle, Julien Dumont, Tristan Piolot, Aurélien Dauphin, Fanny Coulpier, Alain Chédotal, Jean-Léon Maître, Marie-Hélène Verlhac, Hugh J Clarke, Marie-Emilie Terret
Publikováno v:
Life Science Alliance
Life Science Alliance, 2023, 6 (6), pp.e202301963. ⟨10.26508/lsa.202301963⟩
Life Science Alliance, 2023, 6 (6), pp.e202301963. ⟨10.26508/lsa.202301963⟩
The oocyte must grow and mature before fertilization, thanks to a close dialogue with the somatic cells that surround it. Part of this communication is through filopodia-like protrusions, called transzonal projections (TZPs), sent by the somatic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6970b55a06ea4d7bc00a5bb44033218
https://hal.science/hal-04043467/file/e202301963.full.pdf
https://hal.science/hal-04043467/file/e202301963.full.pdf
Autor:
Sofia Granados-Aparici, Alexander Volodarsky-Perel, Qin Yang, Sibat Anam, Togas Tulandi, William Buckett, Weon-Young Son, Grace Younes, Jin-Tae Chung, Shaoguang Jin, Marie-Emilie Terret, Hugh J Clarke
Publikováno v:
Biol Reprod
Granulosa cells of growing ovarian follicles elaborate filopodia-like structures termed transzonal projections (TZPs) that supply the enclosed oocyte with factors essential for its development. Little is known, however, of the mechanisms underlying t
Autor:
Hugh J. Clarke
Publikováno v:
Human Reproductive and Prenatal Genetics ISBN: 9780323913805
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41f89a1fd96d12798b08eaa627992f27
https://doi.org/10.1016/b978-0-323-91380-5.00023-x
https://doi.org/10.1016/b978-0-323-91380-5.00023-x
Autor:
Vimla Aggarwal, T.M. Barber, Christian M. Becker, Karanveer Bhangu, Mats Brännström, Carolyn J. Brown, Richard O. Burney, Antonio Capalbo, Wai-Yee Chan, Andy Chun Hang Chen, Chien-Wen Chen, Ming-Jer Chen, Zi-Jiang Chen, Ya-Ching Chou, Kwong Wai Choy, Hugh J. Clarke, Marcos Cordoba, Pernilla Dahm-Kähler, Mo-Yu Dai, Jessica Garcia de Paredes, Guo-Lian Ding, Zirui Dong, Jin Du, C. Eguizabal, Heather E. Fice, S. Franks, Qing-Qin Gao, Jessica Giordano, Linda C. Giudice, Jordan Gosnell, Ting Guo, Meade Haller, Tristan Hardy, Qilong He, L. Herrera, Ali Honaramooz, Cheng Huang, He-Feng Huang, Ghada Hussein, Sylvie Jaillard, Hai-Ping Jiang, Zi-Ru Jiang, Laura Kasak, Kazuhiro Kawamura, Ali Khatibi, Chaini Konwar, Maris Laan, Guan-Lin Lai, Jonathan LaMarre, Dolores J. Lamb, Yin Lau Lee, Yi-Xuan Lee, Brynn Levy, Xin-Yuan Li, Yao Li, Yu-Fei Li, Jinyue Liao, Ming Liu, Xiaodong Liu, Xin-Mei Liu, Y.M. Dennis Lo, Xinyi Ma, Yun-Yi Ma, M. Martin-Inaraja, Stacey A. Missmer, Kai Kei Miu, Grant Montgomery, N. Montserrat, Cynthia C. Morton, Maria Jose Navarro-Cobos, Robert J. Norman, Marisol O’Neill, Fanghong Ou, Yanli Pang, Maria S. Peñaherrera, Maurizio Poli, Jose M. Polo, Jie Qiao, Yingying Qin, Endah Rahmawati, Nilufer Rahmioglu, Bernard Robaire, Wendy P. Robinson, Alice P. Rogers, Peter A.W. Rogers, I. Romayor, Kristiina Rull, Victor A. Ruthig, Matthew A. Shanahan, Xuan Shao, Andrew H. Sinclair, Leanne Stalker, Kate Stanley, Melissa Stosic, Michael Strug, Hoi-Ching Suen, Jia Ping Tan, Jose M. Teixeira, Nannan Thirumavalavan, Jason C.H. Tsang, Allison Tscherner, Elena J. Tucker, Chii-Ruey Tzeng, Ignatia B. Van den Veyver, Margot van Riel, Joris R. Vermeesch, Liesbeth Vossaert, Wei Wang, Yan-Ling Wang, Zhangting Wang, Ronald Wapner, Nicholas Werry, Jeffrey T. White, Samantha L. Wilson, Jun Wu, Peng Xu, Liying Yan, Zhiqiang Yan, William Shu Biu Yeung, Stephanie C.Y. Yu, Peng Yuan, Victor Yuan, Fan Zhai, Shidou Zhao, Yue Zhao, Boryana Zhelyazkova, Qi Zhou, Krina Zondervan
Publikováno v:
Human Reproductive and Prenatal Genetics ISBN: 9780323913805
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e021dcf019339c562794328d6b30c9fc
https://doi.org/10.1016/b978-0-323-91380-5.09990-1
https://doi.org/10.1016/b978-0-323-91380-5.09990-1
Autor:
Adam E. Goetz, Husein Becirovic, Florian Blasberg, Bo Chen, Hugh J. Clarke, Matteo Colombo, Pedro Daddario, David B. Damon, Christelle Depretz, Yves R. Dumond, Maria D. Grilli, Lu Han, Tim L. Houck, Amber M. Johnson, Kris N. Jones, Jörg Jung, Michel Leeman, Fangfang Liu, Cuong V. Lu, Emilio J. Mangual, Jade D. Nelson, Angela L. A. Puchlopek-Dermenci, Sally Gut Ruggeri, Paul A. Simonds, Barbara Sitter, Daniel E. Virtue, Shuguang Wang, Lixin Yu, Tao Yu
Publikováno v:
Organic Process Research & Development. 26:683-697
Autor:
Hugh J. Clarke
Publikováno v:
Molecular reproduction and developmentREFERENCES. 89(11)
The development of germ cells relies on contact and communication with neighboring somatic cells that provide metabolic support and regulatory signals. In females, contact is achieved through thin cytoplasmic processes that project from follicle cell