Zobrazeno 1 - 10
of 12 551
pro vyhledávání: '"Hugh J"'
Publikováno v:
Radiation, Vol 4, Iss 3, Pp 276-308 (2024)
Vibrational spectroscopic techniques, such as Fourier transform infrared (FTIR) absorption and Raman spectroscopy (RS), offer unique and detailed biochemical fingerprints by detecting specific molecular vibrations within samples. These techniques pro
Externí odkaz:
https://doaj.org/article/636df0f96a8f40648900ea07fc830557
Publikováno v:
FEBS Open Bio, Vol 14, Iss 8, Pp 1247-1263 (2024)
Exploring cellular responses necessitates studying real‐time metabolic pathway kinetics, considering the adaptable nature of cells. Glycolysis and glutaminolysis are interconnected pathways fundamental to driving cellular metabolism, generating bot
Externí odkaz:
https://doaj.org/article/b7e2636415cc46b682a77faa27d762a4
Autor:
Antony J. Birchill, Chelsey A. Baker, Neil J. Wyatt, Katsiaryna Pabortsava, Hugh J. Venables, C. Mark Moore, Isobel Turnbull, Angela Milne, Simon J. Ussher, Sophy Oliver, Adrian P. Martin
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-10 (2024)
Abstract Scarcity of iron and manganese limits the efficiency of the biological carbon pump over large areas of the Southern Ocean. The importance of hydrothermal vents as a source of these micronutrients to the euphotic zone of the Southern Ocean is
Externí odkaz:
https://doaj.org/article/fe64e351a2074de7a6906bcfd285e0a7
Autor:
Emily Freeman, Stéphanie Langlois, Marcos F. Leyba, Tarek Ammar, Zacharie Léger, Hugh J. McMillan, Jean-Marc Renaud, Bernard J. Jasmin, Kyle N. Cowan
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background Duchenne muscular dystrophy (DMD) is associated with impaired muscle regeneration, progressive muscle weakness, damage, and wasting. While the cause of DMD is an X-linked loss of function mutation in the gene encoding dystrophin,
Externí odkaz:
https://doaj.org/article/26454c7be8214472a0a10cfc640b0b48
Publikováno v:
FEBS Open Bio, Vol 14, Iss 3, Pp 466-486 (2024)
This study aims to demonstrate the benefits of augmenting commercially available, real‐time, in vitro glycolysis assays with phenomenological rate equation‐based kinetic models, describing the contributions of the underpinning metabolic pathways.
Externí odkaz:
https://doaj.org/article/bc0a711138f9481f8a198997f926b17b
Autor:
Matthew A. Petoe, BEng (Hons), PhD, Carla J. Abbott, BOptom, PhD, Samuel A. Titchener, BEng (Hons), PhD, Maria Kolic, BOrth, William G. Kentler, BEng, David A.X. Nayagam, BEng (Hons), PhD, Elizabeth K. Baglin, BOrth, Jessica Kvansakul, MSc, PhD, Nick Barnes, PhD, Janine G. Walker, PhD, Lewis Karapanos, BBMed (Hons), MD, Myra B. McGuinness, MBiostat, PhD, Lauren N. Ayton, BOptom, PhD, Chi D. Luu, BOrth (Hons), PhD, Penelope J. Allen, MBBS, FRANZCO, Peter J. Blamey, Robert J. Briggs, Owen Burns, Stephanie B. Epp, Dean Johnson, Hugh J. McDermott, Ceara McGowan, Rodney E. Millard, Peter M. Seligman, Robert K. Shepherd, Mohit N. Shivdasani, Nicholas C. Sinclair, Patrick C. Thien, Joel Villalobos, Chris E. Williams, Jonathan Yeoh, Kiera A. Young
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100525- (2025)
Purpose: To assess the feasibility of a second-generation (44-channel) suprachoroidal retinal prosthesis for provision of functional vision in recipients with end-stage retinitis pigmentosa (RP) over 2.7 years. Design: Prospective, single-arm, unmask
Externí odkaz:
https://doaj.org/article/3a20a1a10d28475b9c47d7d3672f0e3e
Publikováno v:
eLife, Vol 13 (2024)
Development of the mammalian oocyte requires physical contact with the surrounding granulosa cells of the follicle, which provide it with essential nutrients and regulatory signals. This contact is achieved through specialized filopodia, termed trans
Externí odkaz:
https://doaj.org/article/17a9b38352bf41f287035a338dc5f68c
Autor:
Francesco Muntoni, Barry J. Byrne, Hugh J. McMillan, Monique M. Ryan, Brenda L. Wong, Juergen Dukart, Amita Bansal, Valerie Cosson, Roxana Dreghici, Maitea Guridi, Michael Rabbia, Hannah Staunton, Giridhar S. Tirucherai, Karl Yen, Xiling Yuan, Kathryn R. Wagner, the Taldefgrobep Alfa Study Group
Publikováno v:
Neurology and Therapy, Vol 13, Iss 1, Pp 183-219 (2024)
Abstract Introduction Duchenne muscular dystrophy (DMD) is a genetic muscle disorder that manifests during early childhood and is ultimately fatal. Recently approved treatments targeting the genetic cause of DMD are limited to specific subpopulations
Externí odkaz:
https://doaj.org/article/202c472942a04da4895185c648dc27dc
Autor:
Joana A. Moura, Hugh J. Barlow, Shareen H. Doak, Karl Hawkins, Iris Muller, Martin J. D. Clift
Publikováno v:
Journal of Functional Biomaterials, Vol 15, Iss 9, p 265 (2024)
A hallmark of angiogenesis is the sprouting of endothelial cells. To replicate this event in vitro, biomaterial approaches can play an essential role in promoting cell migration. To study the capacity of a scaffold of fibrin (fibrinogen:thrombin mix)
Externí odkaz:
https://doaj.org/article/46b8d699eee14c9b8f4d8c196c06b0ec
Autor:
Natalie D. King-Lyons, Aryana S. Bhati, John C. Hu, Lorrie M. Mandell, Gautam N. Shenoy, Hugh J. Willison, Terry D. Connell
Publikováno v:
Toxins, Vol 16, Iss 7, p 311 (2024)
Triple-negative breast cancer (TNBC), which constitutes 10–20 percent of all breast cancers, is aggressive, has high metastatic potential, and carries a poor prognosis due to limited treatment options. LT-IIc, a member of the type II subfamily of A
Externí odkaz:
https://doaj.org/article/b2bb70b42ab04c53a06f52671703fe65