Výsledky vyhledávání - "Hugh F. Pross"

P-glycoprotein-mediated multidrug resistance and lymphokine-activated killer cell susceptibility in ovarian carcinoma

Autor: Takashi Tsuruo, Hugh F. Pross, B. Savas, Susan P.C. Cole

Publikováno v: Journal of Clinical Immunology. 16:348-357

The sensitivity of tumor cells to lysis by natural killer (NK) and interleukin-2 (IL-2)-activated killer (LAK) cells was studied in three ovarian carcinoma cell lines (2780.9S, SKOV-3, and CHOAUXB1), four multidrug-resistant (MDR) variants, and a mel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e09167c24c23c212aa01ac2045e99b3
https://doi.org/10.1007/bf01541671

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Anti-β1Integrin IgG Inhibits Pulmonary Macrometastasis and the Size of Micrometastases from a Murine Mammary Carcinoma

Autor: Hugh F. Pross, Bruce E. Elliott, Kristofer Rubin, Audrey Niemann, Peter Ekblom

Publikováno v: Cell Adhesion and Communication. 1:319-332

In the present report, we investigated the possible importance of beta 1 integrins in the growth and metastasis of a murine mammary carcinoma, SP1, and a metastatic variant, SP1-3M in vivo. CBA/J female mice bearing SP1 tumor transplants were injecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b1c4d9624a28751d3cd02be1b0015d
https://doi.org/10.3109/15419069409097263

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p21ras and protein kinase C function in distinct and interdependent signaling pathways in C3H 10T1/2 fibroblasts

Autor: A. Krook, Tina Haliotis, S K Anderson, Yu Chun Zhou, T. L. Delovitch, D. T. Denhardt, M. J. Rapoport, Hugh F. Pross

Publikováno v: Molecular and Cellular Biology. 13:1471-1479

Both p21ras and protein kinase C (PKC) are believed to function downstream of plasma membrane-associated tyrosine kinases in cellular signal transduction pathways. However, it has remained controversial whether they function in the same pathway and,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69d26473f3c4607bed66ac561e3400e6
https://doi.org/10.1128/mcb.13.3.1471

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Ras modulates commitment and maturation of 10T½ fibroblasts to adipocytes

Autor: Tina Haliotis, Steve Anderson, Ying Lu, Michael J. Corbley, Leda Raptis, Hugh F. Pross, Yu-Chun Zhou

Publikováno v: Biochemistry and Cell Biology. 70:1249-1257

The positive association of the ras oncogene with human cancer and the recognition that malignancy may, in part, represent the imbalance between cell proliferation and differentiation have generated intense interest in the potential role of ras in ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4896079a91be493c179b6d07b59300d
https://doi.org/10.1139/o92-171

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Capacity of CD8+ T Cells to Reject Immunogenic Variants of a Spontaneous Murine Carcinoma: Lack of Non-Specific (NK1.1+) Effector Mechanisms

Autor: S. Macnaughton, D. A. Carlow, Bruce E. Elliott, A. Barron, L. Maxwell, Hugh F. Pross

Publikováno v: Scandinavian Journal of Immunology. 33:683-690

Class I MHC-expressing (Ia-) immunogenic (imm +) variants, which elicit a strong syngeneic host immune rejection response, can be isolated following 5-azacytidine treatment from the MHC-negative non-immunogenic (imm-) murine carcinoma cell line SP1 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ddf1885e84d913b0378d3fc2c61e8b
https://doi.org/10.1111/j.1365-3083.1991.tb02541.x

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Lymphokine-activated killer cell susceptibility and adhesion molecule expression of multidrug resistant breast carcinoma

Autor: Burhan Savas, Hugh F. Pross, Pauline E Kerr

Publikováno v: Cancer Cell International
Cancer Cell International, Vol 6, Iss 1, p 24 (2006)

Reports showing susceptibility of multidrug resistant (MDR) cancer cells to immune effectors, together with P-glycoprotein (P-gp) expression in immune effector subsets, including immature natural killer (NK) cells, and some activated T cells, suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100e10546e8ef87d971fdc6e986827b7
https://doi.org/10.1186/1475-2867-6-24

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Effects of lovastatin on natural killer cell function and other immunological parameters in man

Autor: Malcolm G. Baines, Robert V. Zupkis, Alan Vost, Ruth McPherson, Hugh F. Pross, Chris Tsoukas, Michael Melino

Publikováno v: Journal of clinical immunology. 13(6)

Suppression of cholesterol synthesis by 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, such as lovastatin, has been shown to inhibit mitogen stimulated proliferation of natural killer (NK) cells and other lymphocytes in vitro.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7eb155c752cc3caabd6c200ae45868
https://pubmed.ncbi.nlm.nih.gov/8288727

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Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. V. The role of serum-derived heterologous membrane antigens

Autor: Malcolm G. Baines, Samuel S. Luk, Hugh F. Pross

Publikováno v: International Journal of Cancer. 21:291-298

The effect of serum on the K562 assay for spontaneous human lymphocyte-mediated cytotoxicity (SLMC) was examined systematically at the level of the assay system and with respect to the serum used for the long-term maintenance of the K562 target cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff216aa20f57279291efb205bbfc298
https://doi.org/10.1002/ijc.2910210307

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