Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Hugh D. Niall"'
Autor:
Hugh D. Niall, Peter J. Hudson, John P. Coghlan, Jennifer D. Penschow, E. Simpson, J. W. Jacobs
Publikováno v:
Endocrinology. 113:1616-1622
DNA/RNA hybridization assays have been used to examine calcitonin (CT) RNA production in normal rat thyroids. A cloned CT cDNA which codes for the entire rat CT precursor was radiolabeled to a high specific activity and used in hybridization assays t
Autor:
D. Scanlon, M. Cronk, Hugh D. Niall, Peter J. Hudson, John D. Haley, John Shine, Geoffrey William Tregear, M. John
Publikováno v:
DNA. 1:155-162
Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy, softening and lengthening the ligaments of the pelvis and softening the cervix in order to make childbirth easier. In attempts to determine the nucleotide sequenc
Autor:
Peter J. Hudson, Robert J. Crawford, Geoffrey William Tregear, D. Scanlon, John D. Haley, John Shine, Hugh D. Niall
Publikováno v:
Journal of Biological Chemistry. 262:11940-11946
A porcine genomic cosmid library was constructed to study the structure and regulation of the porcine relaxin gene. Two overlapping cosmids containing relaxin-specific sequences were isolated, and a 9-kilobase BamHI fragment containing the porcine re
Publikováno v:
Biochemistry. 14:1842-1847
The sequence of the amino-terminal portion of human parathyroid hormone, particularly the identity of residues 22, 28, and 30 (the subject of discrepancies in recent published reports), has been reexamined by two basic methods of structural analysis.
Autor:
David V. Cohn, Henry T. Keutmann, Hugh D. Niall, John T. Potts, James W. Hamilton, John W. Jacobs
Publikováno v:
Proceedings of the National Academy of Sciences. 71:653-656
Proparathyroid hormone (calcemic fraction-A) is a biosynthetic precursor of parathyroid hormone in bovine glands. Limited amounts of the isolated prohormone have been obtained for the purpose of initial structural studies. The results of automated se
Autor:
Ralph A. Bradshaw, William A. Frazier, Ruth A. Hogue-Angeletti, Hugh D. Niall, John W. Jacobs
Publikováno v:
Biochemistry. 15:26-34
The nerve growth factor (NGF) from Naja naja (cobra) venom has been purified and its structure compared to the NGF from mouse submaxillary gland. A two-step purification procedure has been devised, consisting of a gel filtration step in 1 M acetic ac
Publikováno v:
The American Journal of Medicine. 56:774-784
Recent findings concerning the metabolism of parathyroid hormone (PTH) and the heterogeneity, or multiple forms, of circulating PTH have spurred widespread investigation of the nature, origin and physiologic significance of the circulating fragments
Publikováno v:
Annals of the New York Academy of Sciences. 383:329-342
Publikováno v:
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 81:509-513
1. 1. Lysozyme (muramidase) was isolated from an acidic extract of human foetal membranes by adsorption and elution from octadecyl silica. It was further purified by gel-filtration and ion-exchange. 2. 2. The final product was homogeneous by high per
Autor:
Neil Isaacs, Guy Dodson, Hugh D. Niall, Alan Evans, Anthony C.T. North, Gillian D. Bryant-Greenwood, Robert B. James
Publikováno v:
Nature. 271:278-281
THE sequence of the ovarian peptide, relaxin, has recently been reported1,2 and the observation1 that it can be accommodated into the insulin fold has been discussed3,4. Only 11 residues, including the cystines, are common to insulin and relaxin (Fig