Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Huey-Shin Lin"'
Autor:
Robert J. Weinkam, Huey-Shin Lin
Publikováno v:
Journal of Medicinal Chemistry. 22:1193-1198
Products formed from the reaction of two chloroethylnitrosoureas in neutral aqueous solution have been identified and quantified. Mixture components recovered after a 1-h incubation period accounted for 75--85% of the starting nitrosourea. Approximat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392dbe7d6d6a0c92e7d262dd5262c93a
https://doi.org/10.1021/jm00196a009
https://doi.org/10.1021/jm00196a009
Autor:
René H. Levy, Huey-shin Lin
Publikováno v:
Epilepsia. 24:692-702
Stiripentol is a new anticonvulsant drug derived from phenyl-l-pentene-ol. One of its metabolites resulting from opening of the methylenedioxy ring also possesses anticonvulsant activity. This study undertook to define the overall pharmacokinetic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44eeb826b453fc3b1a8a9c31484a3859
https://doi.org/10.1111/j.1528-1157.1983.tb04632.x
https://doi.org/10.1111/j.1528-1157.1983.tb04632.x
Autor:
Huey-shin. Lin, R. J. Weinkam
Publikováno v:
Analytical Chemistry. 51:972-975
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb836eaf4e7ddad027859efc59cc428
https://doi.org/10.1021/ac50043a044
https://doi.org/10.1021/ac50043a044
Publikováno v:
The Journal of Clinical Pharmacology. 23:523-533
The pharmacokinetics and metabolism of stiripentol, a new antiepileptic drug, were investigated in normal male subjects after single-dose and multiple-dose administration. Each of six subjects received single doses of 300, 600, and 1200 mg of stiripe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8927a5c08f0d5e5df428b06e07a9fc15
https://doi.org/10.1002/j.1552-4604.1983.tb01799.x
https://doi.org/10.1002/j.1552-4604.1983.tb01799.x
Autor:
Robert J. Weinkam, Huey-Shin Lin
Publikováno v:
Journal of Medicinal Chemistry. 24:761-763
The in vitro metabolism of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) has been studied in male Fischer 344 rat liver microsomal preparations. The previously identified product. 1,3-bis(2-chloroethyl)urea (BCU), has been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7d2dd38379070d17754b971a87246f
https://doi.org/10.1021/jm00138a025
https://doi.org/10.1021/jm00138a025
Autor:
Huey-Shin Lin, Robert J. Weinkam
Publisher Summary This chapter discusses the chloroethylnitrosourea cancer chemotherapeutic agents. Chloroethylnitrosoureas have proven to be highly effective cancer chemotherapeutic agents that are in common clinical use. Along with the developments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99ead3caa215f02308014981e07981a
https://doi.org/10.1016/s1054-3589(08)60019-8
https://doi.org/10.1016/s1054-3589(08)60019-8
Publikováno v:
Journal of pharmaceutical sciences. 73(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162a2e0fe1eb4dcdc6697aba4f2593c5
https://pubmed.ncbi.nlm.nih.gov/6707907
https://pubmed.ncbi.nlm.nih.gov/6707907
Autor:
Robert J. Weinkam, Huey-Shin Lin
Publikováno v:
Chemischer Informationsdienst. 11
Products formed from the reaction of two chloroethylnitrosoureas in neutral aqueous solution have been identified and quantified. Mixture components recovered after a 1-h incubation period accounted for 75--85% of the starting nitrosourea. Approximat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b1e4da909d173e952cc8ae983e5264b
https://doi.org/10.1002/chin.198009171
https://doi.org/10.1002/chin.198009171
Autor:
Robert J. Weinkam, Huey-Shin Lin
Publikováno v:
Chemischer Informationsdienst. 12
The in vitro metabolism of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) has been studied in male Fischer 344 rat liver microsomal preparations. The previously identified product. 1,3-bis(2-chloroethyl)urea (BCU), has been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::081bf779f57d122c52fa321ba3b3ad67
https://doi.org/10.1002/chin.198144133
https://doi.org/10.1002/chin.198144133
Publikováno v:
In Chemico-Biological Interactions 1980 31(2):167-177