Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Huey-Jiun Ko"'
Autor:
Thi-Huong Nguyen, Huey-Jiun Ko, Po-Yu Tsai, Tai-Shan Cheng, Thu-Ha Tran, Ly Hien Doan, Michael Hsiao, Peter Mu-Hsin Chang, Hsiao-Sheng Liu, Yi-Ren Hong, Chi-Ying F. Huang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Colorectal cancer (CRC) is one of the primary contributors to cancer-related fatalities, with up to 80% of advanced CRC cases exhibiting mutations in the p53 gene. Unfortunately, the development of new compounds targeting mutant p53 is quite limited.
Externí odkaz:
https://doaj.org/article/175e1107fd754719a53e6fa4e741b36b
Autor:
Huey-Jiun Ko, Shean-Jaw Chiou, Cheng-Yu Tsai, Joon-Khim Loh, Xin-Yi Lin, Thu-Ha Tran, Chia-Chung Hou, Tai-Shan Cheng, Jin-Mei Lai, Peter Mu-Hsin Chang, Feng-Sheng Wang, Chun-Li Su, Chi-Ying F. Huang, Yi-Ren Hong
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Despite advances in treatment, patients with refractory colorectal cancer (CRC) still have poor long-term survival, so there is a need for more effective therapeutic options. Methods To evaluate the HDAC8 inhibition efficacy as a
Externí odkaz:
https://doaj.org/article/a85328dd6583484aa3db73984752d583
Autor:
Cheng-Jung Ho, Huey-Jiun Ko, Tzu-Shao Liao, Xiang-Ren Zheng, Po-Hsu Chou, Li-Ting Wang, Ru-Wei Lin, Chung-Hwan Chen, Chihuei Wang
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Apoptosis induced by doxorubicin, bortezomib, or paclitaxel, targeting DNA, 26S proteasome, and microtubules respectively, was assessed in two osteosarcoma cells, p53 wild-type U2OS and p53-null MG63 cells. Doxorubicin-induced apoptosis only
Externí odkaz:
https://doaj.org/article/1fa50be3d49b45e6aa944eb481cc7da2
Autor:
Cheng-Yu Tsai, Shean-Jaw Chiou, Huey-Jiun Ko, Yu-Fan Cheng, Sin-Yi Lin, Yun-Ling Lai, Chen-Yen Lin, Chihuei Wang, Jiin-Tsuey Cheng, Hsin-Fu Liu, Aij-Li Kwan, Joon-Khim Loh, Yi-Ren Hong
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262138 (2022)
We previously revealed the origin of mammalian simple-type glycogen synthase kinase interaction protein (GSKIP), which served as a scavenger and a competitor in the Wnt signaling pathway during evolution. In this study, we investigated the conserved
Externí odkaz:
https://doaj.org/article/9bcf12eea0c642c1bb448d1bcd93e18f
Autor:
Chia-Chih Tsai, Yu-Feng Su, Feng-Ji Tsai, Hui-Yuan Su, Huey-Jiun Ko, Yung-Han Cheng, Yu-Li Chen, Cheng-Yu Tsai
Publikováno v:
Medicina, Vol 58, Iss 8, p 1126 (2022)
Background and Objectives: Supplementary motor area (SMA) syndrome is a common post-operation complication in intra-axial brain tumors, such as glioma. Direct damage to parenchyma or scarification of the major vessels during an operation are the main
Externí odkaz:
https://doaj.org/article/c5007041dc1f46b49e475b25e4122f8c
Autor:
Hui-Yuan Su, Huey-Jiun Ko, Yu-Feng Su, Ann-Shung Lieu, Chih-Lung Lin, Chih-Hui Chang, Tai-Hsin Tsai, Cheng-Yu Tsai
Publikováno v:
Medicina, Vol 58, Iss 5, p 688 (2022)
Background and Objectives: Minimally invasive spine surgery reduces destruction of the paraspinal musculature and improves spinal stability. Nevertheless, screw loosening remains a challenging issue in osteoporosis patients receiving spinal fixation
Externí odkaz:
https://doaj.org/article/d3cd075133df46b9be0ea0ba322deacd
Publikováno v:
Interdisciplinary Neurosurgery, Vol 22, Iss , Pp 100798- (2020)
Iliopsoas abscess is a rare medical infection disease. Clinical finding was fluid or/with pus accumulated inside the iliopsoas muscle compartment. Most cases of iliopsoas abscess were unilateral site. Bilateral iliopsoas abscesses were rare and also
Externí odkaz:
https://doaj.org/article/c7e21c0f2a1944a1af0a916263bd47f5
Autor:
Cheng-Yu Tsai, Huey-Jiun Ko, Shean-Jaw Chiou, Xin-Yi Lin, Tsung-Hsien Chuang, Jiin-Tsuey Cheng, Yu-Feng Su, Joon-Khim Loh, Yi-Ren Hong
Publikováno v:
Journal of Cell Communication and Signaling.
GSK3β interacting protein (GSKIP) is a small A-kinase anchor protein previously reported to mediate the N-cadherin/β-catenin pool for differentiation in SH-SY5Y cells through overexpression of GSKIP to present the neuron outgrowth phenotype. To fur
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6330 (2021)
Beta2-microglobulin (B2M) a key component of major histocompatibility complex class I molecules, which aid cytotoxic T-lymphocyte (CTL) immune response. However, the majority of studies of B2M have focused only on amyloid fibrils in pathogenesis to t
Externí odkaz:
https://doaj.org/article/11545c20a98549dca313ff7f24143f52
Autor:
Cheng-Yu Tsai, Huey-Jiun Ko, Shean-Jaw Chiou, Yu-Ling Lai, Chia-Chung Hou, Tehseen Javaria, Zi-Yi Huang, Tai-Shan Cheng, Tsung-I Hsu, Jian-Ying Chuang, Aij-Lie Kwan, Tsung-Hsien Chuang, Chi-Ying F. Huang, Joon-Khim Loh, Yi-Ren Hong
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5907 (2021)
Although histone deacetylase 8 (HDAC8) plays a role in glioblastoma multiforme (GBM), whether its inhibition facilitates the treatment of temozolomide (TMZ)-resistant GBM (GBM-R) remains unclear. By assessing the gene expression profiles from short h
Externí odkaz:
https://doaj.org/article/fc6e2fcfbde94b2591bc6f51ec969134