Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Hueng Sik Choi"'
Autor:
Yoon Seok Jung, Kamalakannan Radhakrishnan, Seddik Hammad, Sebastian Müller, Johannes Müller, Jung-Ran Noh, Jina kim, In-Kyu Lee, Sung Jin Cho, Don-Kyu Kim, Yong-Hoon Kim, Chul-Ho Lee, Steven Dooley, Hueng-Sik Choi
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103107- (2024)
Fibroblast growth factor 23 (FGF23) is a member of endocrine FGF family, along with FGF15/19 and FGF21. Recent reports showed that under pathological conditions, liver produces FGF23, although the role of hepatic FGF23 remains nebulous. Here, we inve
Externí odkaz:
https://doaj.org/article/e9e4d791e0f4453f94ec197a5cf705a5
Autor:
Yoon Seok Jung, Yong-Hoon Kim, Kamalakannan Radhakrishnan, Jung-Ran Noh, Jung Hyeon Choi, Hyo-Jin Kim, Jae-Ho Jeong, Steven Dooley, Chul-Ho Lee, Hueng-Sik Choi
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 679-682 (2023)
Externí odkaz:
https://doaj.org/article/25f72c83f54546a28c81d6f01d9a2499
Autor:
Yeong-Bin Baek, Hyung-Jun Kwon, Muhammad Sharif, Jeongah Lim, In-Chul Lee, Young Bae Ryu, Jae-In Lee, Ji-Sun Kim, Young-Seung Lee, Dong-Hoon Kim, Sang-Ik Park, Don-Kyu Kim, Jeong-Sun Kim, Hyon E. Choy, Sunwoo Lee, Hueng-Sik Choi, Timothy F. Osborne, Tae-Il Jeon, Kyoung-Oh Cho
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract The biosynthesis of host lipids and/or lipid droplets (LDs) has been studied extensively as a putative therapeutic target in diverse viral infections. However, directly targeting the LD lipolytic catabolism in virus-infected cells has not be
Externí odkaz:
https://doaj.org/article/48b91d4301c04a9aa8ecff65754a81e2
Autor:
Don-Kyu Kim, Hueng-Sik Choi
Publikováno v:
Liver Research, Vol 3, Iss 2, Pp 99-105 (2019)
Estrogen-related receptor gamma (ERRγ) is one of three members of the ERR family and remains an orphan, as there are no known natural ligands. ERRγ is an inducible transcription factor, and its ligand-independent transcriptional activity is regulat
Externí odkaz:
https://doaj.org/article/244c7ac6fe0446a1aa28973d31fc5650
Autor:
Lihua Hao, In Hyuk Bang, Jie Wang, Yuancheng Mao, Jae Do Yang, Soon-Young Na, Jeong Kon Seo, Hueng-Sik Choi, Eun Ju Bae, Byung-Hyun Park
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2020)
Orphan nuclear receptor estrogen-related receptor γ (ERRγ) stimulates bile acid production; however, the role and the regulatory mechanism of ERRγ in cholestatic liver disease are largely unknown. This study identifies that Sirt6 is a deacetylase
Externí odkaz:
https://doaj.org/article/8d84a4fccccd4fcbbee0c3c5d144912b
Autor:
Daejin Lim, Kwang Soo Kim, Jae-Ho Jeong, Oriana Marques, Hyun-Ju kim, Miryoung Song, Tae-Hoon Lee, Jae Il Kim, Hueng-Sik Choi, Jung-Joon Min, Dirk Bumann, Martina U. Muckenthaler, Hyon E. Choy
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The effects of iron on vacuole-resident Salmonella in macrophages are unclear. Here the authors show that the bacteria are not subject to nutritional inhibition by iron deprivation, but that iron depletion in the vacuole, via the hepcidin-ferroportin
Externí odkaz:
https://doaj.org/article/68a93fbb5483477d97468789d3299179
Autor:
Myoung-Hee Kang, Hyunji Choi, Masanobu Oshima, Jae-Ho Cheong, Seokho Kim, Jung Hoon Lee, Young Soo Park, Hueng-Sik Choi, Mi-Na Kweon, Chan-Gi Pack, Ju-Seog Lee, Gordon B. Mills, Seung-Jae Myung, Yun-Yong Park
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Very little is known regarding the molecular mechanisms involved in gastric cancer development. Here the authors show estrogen-related receptor gamma (ESRRG) is a tumor suppressor in gastric cancer and suggest the mechanism of this tumor suppression
Externí odkaz:
https://doaj.org/article/973b51c8851d4d10916c207ff982e196
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1590 (2021)
Hepcidin, a major regulator of systemic iron homeostasis, is mainly induced in hepatocytes by activating bone morphogenetic protein 6 (BMP-6) signaling in response to changes in the iron status. Small heterodimer partner-interacting leucine zipper pr
Externí odkaz:
https://doaj.org/article/1b2ac22c1242433480d83c5b1d58f01e
Autor:
Young-Ok Son, Seulki Park, Ji-Sun Kwak, Yoonkyung Won, Wan-Su Choi, Jinseol Rhee, Churl-Hong Chun, Je-Hwang Ryu, Don-Kyu Kim, Hueng-Sik Choi, Jang-Soo Chun
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The pathogenesis of osteoarthritis is unclear. The authors show that estrogen-related receptor gamma is upregulated in cartilage from patients and mouse models, where it drives production of matrix-degrading MMPs in chondrocytes, and that its downreg
Externí odkaz:
https://doaj.org/article/9254846d1474425a872f6973f8da6d1c
Autor:
Woo-Gyun Choi, Jaeseok Han, Ji-Hyeon Kim, Mi-Jeong Kim, Jae-Woo Park, Benbo Song, Hee-Jeong Cha, Hye-Seon Choi, Hun-Taeg Chung, In-Kyu Lee, Tae-Sik Park, Maria Hatzoglou, Hueng-Sik Choi, Hyun Ju Yoo, Randal J. Kaufman, Sung Hoon Back
Publikováno v:
Nutrition & Metabolism, Vol 14, Iss 1, Pp 1-21 (2017)
Abstract Background Dietary fructose can rapidly cause fatty liver in animals through de novo lipogenesis (DNL) and contribute to the development and severity of nonalcoholic fatty liver disease (NAFLD). In response to diverse cellular insults includ
Externí odkaz:
https://doaj.org/article/622f68c66e374394b6921639e0484074