The anticancer effects of cyanidin 3-O-glucoside combined with 5-fluorouracil on lung large-cell carcinoma in nude mice

Autor: Ching-Feng Wu, Ching-Yang Wu, Chuen-Fu Lin, Yi-Wen Liu, Tzu-Chun Lin, Huei-Jyuan Liao, Geng-Ruei Chang

Publikováno v: Biomedicine & Pharmacotherapy, Vol 151, Iss , Pp 113128- (2022)

The haskap (Lonicera caerulea L., Caprifoliaceae) berry has been widely used in traditional medicine in Kuril Islands, Russia, Japan, and China. Cyanidin-3-O-glucoside (C3G) is the most abundant anthocyanin in haskap berries, and C3G induces antiprol

Externí odkaz: https://doaj.org/article/87504936473c44c7800a443c924d9800

Chronic everolimus treatment of high‐fat diet mice leads to a reduction in obesity but impaired glucose tolerance

Autor: Geng‐Ruei Chang, Po‐Hsun Hou, Chao‐Min Wang, Ching‐Feng Wu, Huang‐Kai Su, Huei‐Jyuan Liao, To‐Pang Chen

Publikováno v: Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)

Abstract Everolimus, which inhibits mTOR kinase activity and is clinically used in graft rejection treatment, may have a two‐sided influence on metabolic syndrome; its role in obesity and hyperglycemic in animals and humans, however, has been explo

Externí odkaz: https://doaj.org/article/7e8e4e4ef35d44a5a360a968c1f7e810

Anti-Cancer Effects of Zotarolimus Combined with 5-Fluorouracil Treatment in HCT-116 Colorectal Cancer-Bearing BALB/c Nude Mice

Autor: Geng-Ruei Chang, Chan-Yen Kuo, Ming-Yang Tsai, Wei-Li Lin, Tzu-Chun Lin, Huei-Jyuan Liao, Chung-Hung Chen, Yu-Chen Wang

Publikováno v: Molecules, Vol 26, Iss 15, p 4683 (2021)

Zotarolimus is a semi-synthetic derivative of rapamycin and an inhibitor of mammalian target of rapamycin (mTOR) signaling. Currently, zotarolimus is used to prolong the survival time of organ grafts, but it is also a novel immunosuppressive agent wi

Externí odkaz: https://doaj.org/article/ba5da054ca934039a3f76d73605d4e62

Mirtazapine Reduces Adipocyte Hypertrophy and Increases Glucose Transporter Expression in Obese Mice

Autor: Ching-Feng Wu, Po-Hsun Hou, Frank Chiahung Mao, Yao-Chi Su, Ching-Yang Wu, Wei-Cheng Yang, Chen-Si Lin, Hsiao-Pei Tsai, Huei-Jyuan Liao, Geng-Ruei Chang

Publikováno v: Animals, Vol 10, Iss 8, p 1423 (2020)

Metabolic syndrome is known to engender type 2 diabetes as well as some cardiac, cerebrovascular, and kidney diseases. Mirtazapine—an atypical second-generation antipsychotic drug with less severe side effects than atypical first-generation antipsy

Externí odkaz: https://doaj.org/article/2756d097e6394f6190b46596c01ae5e8

The Ameliorative Effects of Saikosaponin in Thioacetamide-Induced Liver Injury and Non-Alcoholic Fatty Liver Disease in Mice

Autor: Wei-Li Lin, Huei-Jyuan Liao, Geng-Ruei Chang, Tzu-Chun Lin, Yu-Wen Lu

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11383, p 11383 (2021)
Volume 22
Issue 21

Liver disorders are a major health concern. Saikosaponin-d (SSd) is an effective active ingredient extracted from Bupleurum falcatum, a traditional Chinese medicinal plant, with anti-inflammatory and antioxidant properties. However, its hepatoprotect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb66e9e9e183fd38f42434e62aecc10
http://europepmc.org/articles/PMC8583725