Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Huei-Ju Pan"'
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 11, Pp 1809-1817 (2002)
Successful therapy for chronic diseases must normalize a targeted aspect of metabolism without disrupting the regulation of other metabolic pathways essential for maintaining health. Use of a limited number of single molecule surrogates for disease,
Externí odkaz:
https://doaj.org/article/6a1b422f23f643ff90f73d7edffa299f
Autor:
Chao-Hung Cheng, Yuan-Tsong Chen, Yi-Ching Lee, Chen Chang, Tateki Kikuchi, Nagham George Abd Al-Ahad Sabbagha, Yen-Hui Chen, Huei-Ju Pan
Publikováno v:
Cardiovascular Research. 81:381-388
Aims Glucose transporter 10 (GLUT10), encoded by the SLC2A10 gene, is a member of the class III facilitative glucose transporter family. Mutations in the SLC2A10 gene cause arterial tortuosity syndrome (ATS) in humans. To further study the pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463436c20461e3efa16a9fc256a1904b
https://doi.org/10.1093/cvr/cvn319
https://doi.org/10.1093/cvr/cvn319
Publikováno v:
Vascular Pharmacology. 45:65-71
Given the heterogeneous nature of metabolic dysfunctions associated with insulin resistance and type 2 diabetes (T2D), a single pharmaceutical cannot be expected to provide complication-free therapy in all patients. Thiazolidinediones (TZD) increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74c96b5365ac14ea67a14c087b3b48c
https://doi.org/10.1016/j.vph.2005.11.011
https://doi.org/10.1016/j.vph.2005.11.011
Publikováno v:
Diabetes. 54:1854-1862
Although thiazolidinediones suppress hyperglycemia in diabetic (NON × NZO)F1 males, these mice exhibit unusual sensitivity to drug-induced exacerbation of an underlying hepatosteatosis only rarely experienced in human patients. To establish the phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d828bd0df4a5cad154d1f8f902adab5
https://doi.org/10.2337/diabetes.54.6.1854
https://doi.org/10.2337/diabetes.54.6.1854
Autor:
Christopher Braun, Robert A. Koza, Leslie P. Kozak, Kevin Flurkey, Peter C. Reifsnyder, Huei-Ju Pan, Dawn M. Graunke, Edward H. Leiter
Publikováno v:
Metabolism. 53:799-808
New Zealand Obese (NZO) male mice develop a polygenic juvenile-onset obesity and maturity-onset hyperinsulinemia and hyperglycemia (diabesity). Here we report on metabolic and molecular changes associated with the antidiabesity action of CL316,243 (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160021be66e677f124264c80ac4c22dd
https://doi.org/10.1016/j.metabol.2003.12.024
https://doi.org/10.1016/j.metabol.2003.12.024
Publikováno v:
Journal of Agricultural and Food Chemistry. 52:3360-3365
Territrem B, a fungal metabolite isolated from Aspergillums terreus 23-1, is a tremorgenic mycotoxin. Immunoelectron microscopy using anti-territrem B polyclonal antibody was used to detect territrem B in the fungal body of A. terreus 23-1 at differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeb9dbf21e1e163315f2429095d0d22
https://doi.org/10.1021/jf030787n
https://doi.org/10.1021/jf030787n
Autor:
Linda D. Siracusa, Bastien Llamas, Lisa M. Tarantino, William Valdar, Aldons J. Lusis, Siming Shou, Fuad A. Iraqi, Dabao Zhang, Alexander V. Osadchuk, Frank Lammert, Heinz Himmelbauer, Boris Ivandic, Zonghua Qi, Daniel R. Prows, Willam D. Beavis, Kari J. Buck, Pedro R. Lowenstein, Ariel Darvasi, Fei Zou, Leena Peltonen-Palotie, J. M. Lassalle, James M. Cheverud, Roger H. Reeves, Karen L. Svenson, Howard K. Gershenfeld, Molly A. Bogue, Hans-Willem Snoeck, Nancy L. Hayes, John C. Roder, Karl J. Jepsen, Guy Mittleman, Robert Hitzemann, Howard J. Jacob, Jiri Forejt, Juan F. Medrano, Craig Heller, Richard Mott, Joe M. Angel, Gerald de Haan, Fernando Pardo-Manuel de Villena, Michal Pravenec, Grant Morahan, Kenneth F. Manly, Beverly Paigen, Weikuan Gu, Steve Whatley, Glenn D. Rosen, Kent W. Hunter, Gerd Kempermann, Christina Kendziorski, Margit Burmeister, Jing Gu, Hui-Chen Hsu, Hooman Allayee, Steven J. Clapcote, R. Frank Kooy, Christian F. Deschepper, Linda A. Toth, Rebecca W. Doerge, Ritsert C. Jansen, Ralph S. Marcucio, Steven J. Garlow, John C. Crabbe, Elissa J. Chesler, Beth Bennett, André Bleich, Nengjun Yi, Tom Wiltshire, Kazuhiro Shimomura, Roger D. Cox, Wim E. Crusio, Lu Lu, Hiroki Nagase, Joseph H. Nadeau, Doug Matthews, Leonard C. Schalkwyk, Jeremy L. Peirce, Dabney K. Johnson, Richard S. Nowakowski, Jackson Beatty, Terry Gordon, Beverly A. Mock, Eric E. Schadt, David C. Airey, Wade H. Berrettini, Charles R. Farber, Mikko J. Sillanpää, Xavier Montagutelli, Gary A. Churchill, Jimmy L. Spearow, Daniel Gaile, Darla R. Miller, Huei Ju Pan, Grier P. Page, Melloni N. Cook, Malak Kotb, Thomas E. Johnson, Min Zhang, Karl W. Broman, Hartmut Geiger, David G. Morris, Ze'ev Seltzer, Craig H Warden, Alan D. Attie, Edward S. Buckler, Abraham A. Palmer, Robert W. Williams, David W. Threadgill, John K. Belknap, Jeffrey S. Mogil, Daniel Pomp, Kenneth Paigen, Bruce F. O'Hara
Publikováno v:
Nature genetics
Nature Genetics, 36(11), 1133-1137. Nature Publishing Group
Nature Genetics, 36(11), 1133-1137. Nature Publishing Group
The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fbe78c64861214f31a9f84652155be
https://research.rug.nl/en/publications/fa30153c-07b8-4288-9367-013f6e46cd34
https://research.rug.nl/en/publications/fa30153c-07b8-4288-9367-013f6e46cd34
Autor:
Ta-Min Chang, In Sun Park, William Y. Chey, Cecilia H. Chang, Byeong-Moo Kim, Huei-Ju Pan, Chawnshang Chang
Publikováno v:
Regulatory Peptides. 111:183-190
Secretin is released from upper small intestinal mucosa to drive pancreatic secretion of fluid and bicarbonate and inhibit gastric acid secretion. Recently, we found that, in isolated, vascularly perfused rat stomach model, the inhibition of acid sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b5daf390b473d6b81da9dd157f7e37
https://doi.org/10.1016/s0167-0115(02)00286-0
https://doi.org/10.1016/s0167-0115(02)00286-0
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 11, Pp 1809-1817 (2002)
Successful therapy for chronic diseases must normalize a targeted aspect of metabolism without disrupting the regulation of other metabolic pathways essential for maintaining health. Use of a limited number of single molecule surrogates for disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93acac28639ac969ddd5ca30d3043b25
https://doi.org/10.1194/jlr.m200169-jlr200
https://doi.org/10.1194/jlr.m200169-jlr200
Autor:
Chawnshang Chang, Huei-Ju Pan
Publikováno v:
Molecular and Cellular Biochemistry. 189:195-200
We demonstrate that TR2 orphan receptor (TR2) may induce transactivation activities via an AGGTCA-like-direct-repeat-4 consensus thyroid hormone response element (DR4-TRE) system. TR2 showed a slightly greater binding affinity than thyroid hormone re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8279c1c1dfd9c79149c57244a1cc95ec
https://doi.org/10.1023/a:1006918402474
https://doi.org/10.1023/a:1006918402474