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The 77C→G Mutation in the Human CD45 (PTPRC) Gene Leads to Increased Intensity of TCR Signaling in T Cell Lines from Healthy Individuals and Patients with Multiple Sclerosis

Autor: Reinhard Schwinzer, Wiebke Baars, Katja Borns, Hue-Tran Do, Anja Windhagen

Publikováno v: The Journal of Immunology. 176:931-938

The 77C→G mutation in exon A of the human CD45 gene occurs with low frequency in healthy individuals. An enhanced frequency of 77C→G individuals has been reported in cohorts of patients suffering from multiple sclerosis, systemic sclerosis, autoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081dc30455bd2bb6e15123cc0bb5869c
https://doi.org/10.4049/jimmunol.176.2.931

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